Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   WUE2121_RS01985 Genome accession   NZ_CP012394
Coordinates   373811..376918 (-) Length   1035 a.a.
NCBI ID   WP_079884397.1    Uniprot ID   -
Organism   Neisseria meningitidis strain WUE2121     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 368811..381918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WUE2121_RS13435 - 369375..369542 (-) 168 WP_153312129.1 hypothetical protein -
  WUE2121_RS01960 (WUE2121_0358) - 369546..369935 (-) 390 WP_002221514.1 DUF559 domain-containing protein -
  WUE2121_RS01975 (WUE2121_0359) - 370515..370652 (-) 138 WP_002214606.1 VOC family protein -
  WUE2121_RS01980 (WUE2121_0360) carA 370698..371831 (-) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  WUE2121_RS01985 (WUE2121_0361) pilC 373811..376918 (-) 3108 WP_079884397.1 PilC family type IV pilus tip adhesin Machinery gene
  WUE2121_RS01990 (WUE2121_0362) apbC 377872..378951 (-) 1080 WP_002248129.1 iron-sulfur cluster carrier protein ApbC -
  WUE2121_RS02000 (WUE2121_0363) - 379321..379830 (+) 510 WP_002221509.1 protein disulfide oxidoreductase -
  WUE2121_RS02010 (WUE2121_0364) nadR 380173..380613 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  WUE2121_RS02015 (WUE2121_0365) hpaC 380728..381228 (+) 501 WP_002221506.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1035 a.a.        Molecular weight: 113050.80 Da        Isoelectric Point: 9.6515

>NTDB_id=154197 WUE2121_RS01985 WP_079884397.1 373811..376918(-) (pilC) [Neisseria meningitidis strain WUE2121]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAMAQTYKYAIIMNEQNQPKVKQEGSYSTLREKDRERKFIYNKGGSGGGSVS
FNNSDELVSQQSGTAVFGTATYLPPYGKVSGFDADALKERNNALNWINTTRPGLAGYSYANVICRDTRQCPQLFYETKFA
FSNKDLVNNAGRLDRHPDPSRENSPIYKLKDHPWLGVSFNLGSEGTAKDGKVSNKLISSFSEDNNNQTIVSTTRDHPISL
GDQQREHTAMAYYLNAKLHLLDKKGIKDIAQGKTVDLGTLRPRVETKTNNWGNLLNFWVTWKIEDNGQIPVKLGLPEVKA
GRCTNAAHPNSKAKPPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPGRPGRYSLAALDAQNI
KSHEPRFNGRQTVIRLPGGVYKISLGRNGGRVAGINGNDGKNDTFGIFKDRYVTPEADEWSEMLLPWTVRAFNDDGRFNT
VNKEENNGKPKYSQRYRIRENGNNGKRDLGDIVNSPIVAVGGYLATSANDGMVHIFKQSGGDKRGYNLKLSYIPGTMPRK
NIENNDSTLAKELRAFAEKGYVGDRYGVDGGFVLRQVELSGKKHVFMFGAMGFGGRGAYALDLTKADGNDPTKASLFDVK
DNGNNGNNGNNRVELGYTVGTPQIGKTHNGKYAAFLASGYATKTIDDQQNKTALYVYDLESSGTLIKKIDVPGGKGGLSS
PTLVDKDLDGTVDIAYAGDRGGNMYRFDLSGQDPKQWSVRTIFSGNKPITSAPAISQLKDKRVVIFGTGSDLSEEDVDKM
DEQYIYGIFDDDTAATGTVNFTGTGGGLLEQHLTEENKTLFLTDYKRSDGSGDKGWVVKLEAGQRVTVKPTVVLRTAFVT
IRKYNDGGCGAETAILGINTADGGKLTKKSARPIVPEANTAVAQYSGHKQTANGKSIPIGCMEKDGGTVCPNGYVYDKPV
NVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPTCGMKRISWREIFY

Nucleotide


Download         Length: 3108 bp        

>NTDB_id=154197 WUE2121_RS01985 WP_079884397.1 373811..376918(-) (pilC) [Neisseria meningitidis strain WUE2121]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGCAAACCTATAAATACGCTATTATCATGAACGAACAAAATCAGCCGAAGGTAAAGCAGGAGGGTT
CATATTCAACCTTAAGGGAAAAAGACAGGGAACGCAAATTTATCTATAATAAAGGCGGATCGGGTGGAGGCTCTGTCTCA
TTCAACAATAGCGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCGACGCTCTGAAAGAGCGCAACAATGCCCTTAATTGGATTAATACGACCCGCCCGGGGT
TGGCAGGCTACTCCTACGCCAACGTCATATGCAGAGACACAAGGCAATGCCCCCAACTTTTCTATGAGACCAAATTTGCC
TTCAGCAACAAAGATTTGGTAAACAATGCGGGCAGGCTGGATAGGCACCCGGACCCAAGCCGCGAAAATTCGCCCATTTA
CAAATTGAAGGATCATCCATGGTTGGGCGTATCTTTCAATTTGGGCAGCGAGGGTACCGCCAAAGATGGCAAGGTATCCA
ACAAATTGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACACGAGACCACCCTATTTCCCTT
GGCGACCAGCAGCGCGAACATACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAGGGATTAA
AGATATCGCCCAAGGCAAAACAGTGGATTTGGGCACCTTGAGACCGCGCGTCGAGACGAAGACAAATAATTGGGGGAATC
TGCTAAATTTTTGGGTTACGTGGAAGATTGAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCGGAAGTCAAAGCC
GGGCGCTGCACCAACGCCGCCCACCCCAATTCCAAAGCCAAACCCCCTTCGCCGGCACTGACCGCCCCCGCGCTGTGGTT
CGGCCCTGTGCAAAATGGTAAGGTGCAGATGTATTCCGCTTCGGTTTCTACCTACCCCGGCAGTTCGAGCAGCCGCATCT
TCCTCCAAGAGCTGAAAACTCAAACCGACCCCGGCAGGCCCGGCCGGTATTCCCTCGCCGCTTTGGATGCGCAGAACATC
AAAAGCCACGAGCCGCGTTTCAACGGAAGGCAGACCGTCATCCGATTGCCGGGCGGCGTGTACAAGATCAGCCTGGGCAG
GAACGGCGGCCGGGTCGCGGGTATTAATGGCAATGACGGCAAAAACGACACTTTCGGCATCTTCAAGGACAGGTATGTCA
CACCTGAGGCCGACGAGTGGAGCGAAATGCTGCTGCCTTGGACGGTTCGTGCTTTCAATGATGACGGTCGATTTAACACA
GTCAACAAAGAAGAAAACAACGGCAAGCCAAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAACGGCAAGCG
TGATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGGGTATTTGGCAACTTCTGCCAACGACGGGATGGTGC
ATATCTTCAAACAAAGCGGCGGGGACAAGCGCGGCTACAATCTGAAGCTCAGTTATATCCCGGGTACGATGCCGCGCAAG
AATATTGAAAACAACGACTCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGG
CGTGGACGGCGGCTTTGTCTTGCGCCAAGTCGAACTGAGCGGGAAAAAACACGTGTTTATGTTCGGCGCGATGGGTTTTG
GCGGCAGAGGTGCGTATGCCTTGGATTTGACCAAAGCCGACGGCAATGACCCGACAAAAGCCTCTTTGTTTGATGTAAAA
GATAACGGCAATAATGGCAATAACGGCAATAATCGCGTGGAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAAC
CCACAACGGCAAATACGCCGCTTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACGACCAACAAAATAAAACCGCGC
TGTATGTGTATGATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCC
CCCACGCTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTT
TGATTTGAGCGGTCAAGATCCTAAACAATGGTCTGTACGCACTATTTTTAGTGGCAACAAACCGATTACTTCCGCGCCCG
CCATTTCCCAACTGAAAGACAAACGCGTGGTTATCTTCGGCACGGGCAGCGATTTGAGTGAGGAGGATGTGGACAAAATG
GACGAACAATATATTTACGGTATCTTCGACGACGATACAGCGGCGACGGGTACTGTAAACTTCACCGGTACGGGAGGCGG
GCTGCTCGAGCAACACCTTACTGAGGAAAATAAAACCTTATTCCTGACCGATTATAAGCGATCCGACGGCTCGGGCGACA
AGGGCTGGGTAGTGAAATTGGAAGCCGGACAACGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACC
ATCCGCAAATATAACGACGGCGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGAC
CAAGAAAAGCGCGCGCCCGATTGTGCCAGAAGCCAATACGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCGCCAACG
GCAAATCCATCCCTATAGGTTGTATGGAAAAAGACGGGGGAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTT
AATGTGCGTTATCTGGATGAAAAGAAAACAGACGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATT
CAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGG
ACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAATCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(509-843)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

79.962

100

0.806

Multiple sequence alignment