Detailed information NTG0154058

Bioinformatically predicted

Overview

• Name: dsbA2
• Type: Machinery gene
• Locus tag: DE8669_RS01650
• Genome accession: NZ_CP012391
• Coordinates: 305999..306694 (+)
• Length: 231 a.a.
• NCBI ID: WP_002248140.1
• Uniprot ID: A1KVZ3
• Organism: Neisseria meningitidis strain DE8669
• Function: DNA binding and uptake; interact with PilQ (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	306771..307736	305999..306694	flank	77

Gene organization within MGE regions

Location: 305999..307736

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DE8669_RS01650 (DE8669_0305)	dsbA2	305999..306694 (+)	696	WP_002248140.1	thiol:disulfide interchange protein DsbA/DsbL	Machinery gene
DE8669_RS01655 (DE8669_0306)	-	306771..307736 (-)	966	WP_014575384.1	IS30-like element IS1655 family transposase	-

Sequence

Protein

• Length: 231 a.a.
• Molecular weight: 25378.89 Da
• Isoelectric Point: 5.3625

>NTDB_id=154058 DE8669_RS01650 WP_002248140.1 305999..306694(+) (dsbA2) [Neisseria meningitidis strain DE8669]
MKLKTLALTSLTLLALAACSKQAETSVPADSVQSSSSAPAAPAPLTEGVNYTVLSTPIPQQQAGKVEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEASESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide

• Length: 696 bp

>NTDB_id=154058 DE8669_RS01650 WP_002248140.1 305999..306694(+) (dsbA2) [Neisseria meningitidis strain DE8669]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGCGT
TCCGGCAGACAGCGTCCAAAGCAGCTCATCTGCTCCGGCAGCCCCAGCCCCATTGACCGAAGGCGTGAACTACACTGTAT
TGTCCACGCCTATCCCGCAACAGCAGGCCGGCAAAGTCGAAGTCTTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTTCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATCGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCCGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

• Thioredoxin (Thioredoxin_4) (64-212)

3D structure

• AlphaFold DB: A1KVZ3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dsbA2	Neisseria meningitidis MC58	97.835	100	0.978
dsbA1	Neisseria meningitidis MC58	70.815	100	0.714