Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   DE8669_RS01560 Genome accession   NZ_CP012391
Coordinates   282961..283659 (+) Length   232 a.a.
NCBI ID   WP_002223343.1    Uniprot ID   A0A422SVD5
Organism   Neisseria meningitidis strain DE8669     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 277961..288659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DE8669_RS01540 (DE8669_0281) trpC 279284..280066 (-) 783 WP_002248942.1 indole-3-glycerol phosphate synthase TrpC -
  DE8669_RS01545 (DE8669_0282) - 280116..281072 (-) 957 WP_002248937.1 YheT family hydrolase -
  DE8669_RS01550 (DE8669_0283) murJ 281205..282743 (-) 1539 WP_002248946.1 murein biosynthesis integral membrane protein MurJ -
  DE8669_RS01555 (DE8669_0284) - 282743..282934 (-) 192 WP_002233473.1 hypothetical protein -
  DE8669_RS01560 (DE8669_0285) dsbA1 282961..283659 (+) 699 WP_002223343.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  DE8669_RS01565 (DE8669_0286) amgK 283716..284720 (-) 1005 WP_014581248.1 N-acetylmuramate/N-acetylglucosamine kinase AmgK -
  DE8669_RS01570 (DE8669_0287) - 284790..287198 (+) 2409 WP_025460893.1 LPS-assembly protein LptD -
  DE8669_RS01575 (DE8669_0288) - 287303..288373 (+) 1071 WP_002254205.1 peptidylprolyl isomerase -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 25251.84 Da        Isoelectric Point: 5.1392

>NTDB_id=154057 DE8669_RS01560 WP_002223343.1 282961..283659(+) (dsbA1) [Neisseria meningitidis strain DE8669]
MKSRQLALGVAALFALAACDSKVQTSVPADSAPAASAAAAPAGLVEGQNYTVLANPIPQQQAGKVEVLEFFGYFCPHCAH
LEPVLSKHAKSFKDDMYLRTEHVVWQKEMLPLARLAAAVDMAAADSKDVANSHIFDAMVNQKIKLQEPEVLKKWLGEQTA
FDGKKVLAAYESPESQARADKMQELTETFQIDGTPTVIVGGKYKVEFADWESGMNTIDLLADKVREEQKAAQ

Nucleotide


Download         Length: 699 bp        

>NTDB_id=154057 DE8669_RS01560 WP_002223343.1 282961..283659(+) (dsbA1) [Neisseria meningitidis strain DE8669]
ATGAAATCCAGACAACTCGCCCTCGGCGTTGCCGCCCTGTTCGCCCTTGCCGCGTGCGACAGCAAAGTCCAAACCAGCGT
CCCCGCCGACAGCGCGCCTGCCGCTTCGGCAGCCGCCGCCCCGGCAGGGCTGGTCGAAGGGCAAAACTATACCGTCCTTG
CCAACCCGATTCCCCAACAGCAGGCAGGCAAAGTCGAAGTCCTTGAGTTTTTCGGCTATTTCTGTCCGCACTGCGCCCAC
CTCGAACCTGTTTTGAGCAAACACGCCAAGTCTTTTAAAGACGATATGTACCTGCGTACCGAGCATGTCGTTTGGCAAAA
AGAAATGCTGCCGCTGGCACGCCTCGCCGCCGCCGTCGATATGGCTGCCGCCGACAGCAAAGATGTGGCGAACAGCCATA
TTTTCGATGCGATGGTCAACCAAAAAATCAAGCTGCAAGAGCCGGAAGTCCTCAAAAAATGGCTGGGCGAACAAACCGCC
TTTGACGGCAAAAAAGTCCTTGCCGCCTACGAGTCCCCCGAAAGCCAGGCGCGCGCCGACAAAATGCAGGAGCTGACCGA
AACCTTCCAAATCGACGGTACGCCCACGGTTATCGTCGGCGGTAAATATAAAGTTGAATTTGCCGACTGGGAGTCCGGTA
TGAACACCATCGACCTTTTGGCGGACAAAGTACGCGAAGAACAAAAAGCCGCGCAGTAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(63-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A422SVD5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

98.707

100

0.987
  dsbA2 Neisseria meningitidis MC58

76.72

81.466

0.625

Multiple sequence alignment