Detailed information NTG0153459

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: A6E92_RS18345
• Genome accession: NZ_CP015362
• Coordinates: 4305359..4306483 (-)
• Length: 374 a.a.
• NCBI ID: WP_028416141.1
• Uniprot ID: A0ABY2P794
• Organism: Streptomyces sp. S8
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4300359..4311483

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6E92_RS18320 (A6E92_17985)	cseB	4300576..4301289 (-)	714	WP_018489324.1	two-component system response regulator CseB	-
A6E92_RS18325 (A6E92_17990)	-	4301308..4301958 (-)	651	WP_084994361.1	hypothetical protein	-
A6E92_RS18330 (A6E92_17995)	-	4302126..4302923 (-)	798	WP_084994364.1	SigE family RNA polymerase sigma factor	-
A6E92_RS18335 (A6E92_18000)	-	4303082..4304011 (-)	930	WP_206311907.1	A/G-specific adenine glycosylase	-
A6E92_RS18340 (A6E92_18005)	-	4304263..4305117 (+)	855	WP_187330495.1	hypothetical protein	-
A6E92_RS18345 (A6E92_18010)	disA	4305359..4306483 (-)	1125	WP_028416141.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
A6E92_RS18350 (A6E92_18015)	radA/sms	4306565..4307986 (-)	1422	WP_028416142.1	DNA repair protein RadA	Machinery gene
A6E92_RS18355 (A6E92_18020)	-	4308175..4310184 (+)	2010	WP_203237965.1	hypothetical protein	-
A6E92_RS18360 (A6E92_18025)	-	4310251..4311093 (-)	843	WP_028416144.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40306.25 Da
• Isoelectric Point: 4.9406

>NTDB_id=153459 A6E92_RS18345 WP_028416141.1 4305359..4306483(-) (disA) [Streptomyces sp. S8]
MAANDRAAAPGKSGQGTGNEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKACGFPVVSVSQSMRLIALYVDGERRVLEESSA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDSLSHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=153459 A6E92_RS18345 WP_028416141.1 4305359..4306483(-) (disA) [Streptomyces sp. S8]
GTGGCAGCCAACGACCGGGCGGCAGCGCCCGGAAAGTCCGGCCAAGGCACCGGCAACGAAGCGCTGATGCGCGCCTCGTT
GAGCGCGGTCGCGCCCGGAATGGCCCTGCGGGACGGCCTGGAGCGCATTCTCCGCGGCAACACCGGCGGGCTGATCGTCC
TCGGCATGGACAAGACCGTCGAGTCGATGTGCACCGGCGGGTTCGTGCTGGACGTGGAGTTCACCGCGACCCGGCTGCGG
GAGCTGTGCAAGCTCGACGGGGCGCTGATCCTCGACAAGGACATCACCAAGATCCTGCGGGCCGGGGTACAGCTGGTCCC
GGACGCCTCGATCCCCACGGAGGAGACGGGCACCCGGCACCGCACGGCGGACCGGGTCTCCAAGGCGTGCGGCTTCCCCG
TCGTCTCGGTCTCGCAGTCCATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGGCGGGTCCTGGAGGAGTCGTCCGCG
ATCCTCTCCCGGGCCAACCAGGCCCTCGCCACGCTGGAGCGGTACAAGCTCCGCCTCGACGAGGTGGCCGGCACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTGACGGCGGTGGCGCAGCGGCTGGAGATGGTCCGGCGGATCG
CGACCGAGATCGCGGAGTACGTGGTGGAGCTGGGCACCGACGGCCGGCTCCTCTCGCTCCAGCTGGACGAGCTGATCGCG
GGCGTGGAGCCGGAGCGGGAGCTGGTGGTCCGGGACTATGTGCCCGAGCCGACGGCGAAACGGTCGCGCACGGTGGCGGA
GGCGCTGACGGAGCTGGACTCCCTCAGCCACACGGAGCTGCTGGAGCTGCCGGTGGTGGCGCGGGCGCTGGGGTACAGCG
GCTCGCCGGAGACCCTGGACTCGGCGGTCTCGCCGCGCGGCTTCCGGCTGCTGGCGAAGGTGCCGAGGCTGCCGGGGGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGGGGCCTGCAGAAGCTGCTGGCCGCGAGCGTGGACGACCTCCAGACCGTGGA
CGGAGTCGGCGAGGCGCGGGCGCGCAGCGTGCGGGAGGGGCTCTCGCGGCTGGCGGAGTCGTCGATCCTGGAACGGTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436