Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   V471_RS05110 Genome accession   NZ_CP015283
Coordinates   987986..988738 (+) Length   250 a.a.
NCBI ID   WP_002886759.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 25975     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 982986..993738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS05095 (V471_05025) - 983336..984028 (+) 693 WP_084871171.1 DUF6287 domain-containing protein -
  V471_RS05105 (V471_05035) - 984670..987783 (+) 3114 WP_084871173.1 SH3 domain-containing protein -
  V471_RS05110 (V471_05040) comE/blpR 987986..988738 (+) 753 WP_002886759.1 response regulator transcription factor Regulator
  V471_RS05115 (V471_05045) - 988873..989538 (+) 666 WP_002886760.1 DUF6287 domain-containing protein -
  V471_RS05120 (V471_05050) comE/blpR 989781..990515 (+) 735 WP_002886762.1 response regulator transcription factor Regulator
  V471_RS05125 (V471_05055) - 990512..991831 (+) 1320 WP_045772182.1 GHKL domain-containing protein -
  V471_RS05130 (V471_05060) - 991929..992495 (+) 567 WP_002886764.1 transcriptional regulator -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28684.11 Da        Isoelectric Point: 5.3920

>NTDB_id=153164 V471_RS05110 WP_002886759.1 987986..988738(+) (comE/blpR) [Streptococcus salivarius strain ATCC 25975]
MLDIFVLEEDYFQQARLEDAIHKSKQIYILRIGKVDLYDKPNQLLERITERGSHLLFFLDIGSDSDVEGGILVAQQIRER
DPYASIVFITAHPELLPSTFQYRLAALDFIDKNLPDIEYEDRIISDIGLALSKNGLSQIECAFTIDTKNATIQVPFHKIL
YFETSPTVHKVILHTTEEQIEFYGQLSKVVKQDCRLYKCHKSFVVNPENIVRLDKELGVIYFENGESCLVSKAKQKEIVA
KMLVPKSMAV

Nucleotide


Download         Length: 753 bp        

>NTDB_id=153164 V471_RS05110 WP_002886759.1 987986..988738(+) (comE/blpR) [Streptococcus salivarius strain ATCC 25975]
ATGTTAGATATTTTTGTTTTAGAAGAAGATTATTTTCAACAAGCTCGTCTTGAGGATGCTATCCACAAGTCTAAACAAAT
ATATATTTTAAGAATTGGGAAGGTTGATTTATACGATAAACCCAATCAATTATTAGAGCGTATTACGGAAAGGGGCTCGC
ATTTACTGTTTTTTCTAGATATTGGATCTGACAGTGATGTCGAAGGGGGAATATTGGTTGCTCAACAGATTCGTGAGCGA
GATCCGTATGCAAGTATTGTTTTCATCACAGCACATCCCGAACTCCTACCTTCAACCTTTCAGTATCGCTTAGCTGCACT
TGATTTTATTGACAAGAATTTGCCTGATATTGAATATGAAGATAGGATTATTTCTGATATTGGATTAGCACTTTCTAAAA
ATGGTCTGAGCCAAATAGAGTGTGCTTTTACTATAGATACAAAGAATGCAACTATACAAGTTCCTTTTCATAAGATTCTC
TATTTTGAAACATCTCCAACGGTTCATAAGGTAATTCTTCATACAACAGAAGAGCAAATTGAGTTCTATGGTCAATTATC
AAAAGTTGTAAAACAAGATTGCAGACTATATAAATGCCATAAATCATTTGTTGTAAATCCCGAAAACATTGTGAGATTGG
ACAAAGAATTAGGTGTTATTTATTTTGAAAACGGAGAGTCATGCTTGGTTTCGAAAGCTAAACAAAAAGAGATTGTTGCT
AAGATGCTTGTTCCAAAATCCATGGCAGTTTGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

45.679

97.2

0.444
  comE/comE1 Streptococcus equinus JB1

42.149

96.8

0.408

Multiple sequence alignment