Detailed information NTG0152340

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: A4A60_RS00595
• Genome accession: NZ_CP015222
• Coordinates: 110459..111541 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain HRBS-10TDI13
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 105459..116541

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A4A60_RS00580 (A4A60_00580)	mcsB	105467..106558 (+)	1092	WP_003235007.1	protein arginine kinase	-
A4A60_RS00585 (A4A60_00585)	clpC	106555..108987 (+)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
A4A60_RS00590 (A4A60_00590)	radA/sms	109079..110455 (+)	1377	WP_014475593.1	DNA repair protein RadA	Machinery gene
A4A60_RS00595 (A4A60_00595)	disA	110459..111541 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
A4A60_RS00600 (A4A60_00600)	yacL	111657..112757 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
A4A60_RS00605 (A4A60_00605)	ispD	112772..113470 (+)	699	WP_069837191.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
A4A60_RS00610 (A4A60_00610)	ispF	113463..113939 (+)	477	WP_069837192.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
A4A60_RS00615 (A4A60_00615)	gltX	114030..115481 (+)	1452	WP_014478617.1	glutamate--tRNA ligase	-
A4A60_RS00625 (A4A60_00625)	cysE	115783..116436 (+)	654	WP_014478618.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=152340 A4A60_RS00595 WP_003225736.1 110459..111541(+) (disA) [Bacillus subtilis strain HRBS-10TDI13]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=152340 A4A60_RS00595 WP_003225736.1 110459..111541(+) (disA) [Bacillus subtilis strain HRBS-10TDI13]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTCCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1