Detailed information NTG0150652

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: PA7790_RS12455
• Genome accession: NZ_CP014999
• Coordinates: 2644201..2646477 (+)
• Length: 758 a.a.
• NCBI ID: WP_071501032.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa strain PA7790
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2639201..2651477

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PA7790_RS12435 (PA7790_00236)	-	2639394..2641619 (-)	2226	WP_003116719.1	NADP-dependent isocitrate dehydrogenase	-
PA7790_RS12440 (PA7790_00237)	icd	2641978..2643234 (+)	1257	WP_003090436.1	NADP-dependent isocitrate dehydrogenase	-
PA7790_RS12445 (PA7790_00238)	cspD	2643307..2643579 (-)	273	WP_003090435.1	cold shock domain-containing protein CspD	-
PA7790_RS12450 (PA7790_00239)	clpS	2643805..2644173 (+)	369	WP_003097649.1	ATP-dependent Clp protease adapter ClpS	-
PA7790_RS12455 (PA7790_00240)	clpC	2644201..2646477 (+)	2277	WP_071501032.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
PA7790_RS12460 (PA7790_00241)	infA	2646559..2646777 (-)	219	WP_002553999.1	translation initiation factor IF-1	-
PA7790_RS12465 (PA7790_00242)	-	2646882..2647589 (-)	708	WP_003097644.1	arginyltransferase	-
PA7790_RS12470 (PA7790_00243)	aat	2647644..2648324 (-)	681	WP_003160442.1	leucyl/phenylalanyl-tRNA--protein transferase	-
PA7790_RS12475 (PA7790_00244)	trxB	2648362..2649312 (-)	951	WP_003090421.1	thioredoxin-disulfide reductase	-

Sequence

Protein

• Length: 758 a.a.
• Molecular weight: 84040.75 Da
• Isoelectric Point: 5.8909

>NTDB_id=150652 PA7790_RS12455 WP_071501032.1 2644201..2646477(+) (clpC) [Pseudomonas aeruginosa strain PA7790]
MLNRELEVTLNLAFKEARAKRHEFMTVEHLLLALLDNEAAATVLRACGANLDKLRRDLQEFIDSTTPLIPQHDDERETQP
TLGFQRVLQRAVFHVQSSGKREVTGANVLVAIFSEQESQAVFLLKQQSIARIDVVNYIAHGISKVPGHAEHPQDGEQDMQ
DEEGGESATSNHPLDAYASNLNELARQGRIDPLVGREHEVERVAQILARRRKNNPLLVGEAGVGKTAIAEGLAKRIVDGQ
VPDLLADSVVYSLDLGALLAGTKYRGDFEKRFKALLNELRKRPHAVLFIDEIHTIIGAGAASGGVMDASNLLKPVLSSGE
IRCIGSTTFQEFRGIFEKDRALARRFQKVDVTEPSVEDTYGILKGLKGRFEQHHHIEYSDEALRAAAELAARYINDRHMP
DKAIDVIDEAGAYQRLQPEEKRVKRIEVAQVEDIVAKIARIPPKHVTTSDKELLRNLERELKLTVFGQDDAIESLSTAIK
LSRAGLKAPDKPVGSFLFAGPTGVGKTEVARQLAKALGVELVRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTEAITK
TPHCVLLLDEIEKAHPEVFNLLLQVMDHGTLTDNNGRKADFRNIILIMTTNAGAEVAARASIGFNQQDHTTDAMEVIKKS
FTPEFRNRLDTIIQFGRLSTETIKSVVDKFLTELQAQLEDKRVQLEVSDAARGWLAEKGYDVQMGARPMARLIQDKIKRP
LAEEILFGELAEHGGLVHVDLKGDELAFEFEITAAELA

Nucleotide

• Length: 2277 bp

>NTDB_id=150652 PA7790_RS12455 WP_071501032.1 2644201..2646477(+) (clpC) [Pseudomonas aeruginosa strain PA7790]
ATGTTGAATCGAGAGCTCGAAGTCACCCTCAATCTCGCCTTCAAGGAGGCGAGGGCCAAACGCCATGAATTCATGACGGT
TGAGCACCTGCTGCTGGCCTTGCTGGACAATGAGGCGGCGGCAACGGTATTGCGTGCGTGCGGTGCCAACCTGGACAAGC
TGCGGCGCGACCTGCAGGAATTCATCGATTCCACAACGCCGCTGATCCCGCAGCACGACGACGAGCGCGAAACCCAGCCG
ACGCTGGGCTTCCAGCGCGTCCTGCAGCGTGCGGTGTTCCACGTGCAGAGTTCCGGCAAGCGCGAAGTGACCGGGGCCAA
TGTCCTGGTGGCGATCTTCAGCGAACAGGAAAGCCAGGCGGTGTTCCTGCTCAAGCAGCAGAGCATCGCGCGTATCGATG
TGGTGAACTACATCGCCCATGGTATCTCCAAGGTGCCCGGGCATGCCGAACATCCGCAGGATGGGGAGCAGGATATGCAG
GATGAGGAAGGTGGCGAGTCGGCCACGTCCAACCATCCGCTGGACGCCTATGCCAGCAACCTCAACGAACTGGCTCGCCA
GGGGCGGATCGACCCGCTGGTGGGGCGTGAGCATGAAGTCGAGCGGGTGGCGCAGATCCTTGCCCGCCGGCGCAAGAACA
ACCCGCTGCTGGTAGGCGAGGCGGGGGTCGGCAAGACGGCCATCGCCGAGGGCCTGGCCAAACGCATCGTCGATGGCCAG
GTGCCGGACCTGCTGGCCGACAGCGTGGTCTACTCCCTCGACCTGGGTGCCTTGCTCGCGGGTACCAAGTACCGCGGCGA
CTTCGAGAAGCGCTTCAAGGCCTTGCTCAACGAGTTGCGCAAGCGCCCGCACGCGGTGCTGTTCATCGACGAGATCCATA
CCATCATCGGCGCCGGTGCGGCATCCGGCGGGGTAATGGACGCCTCCAACCTGCTCAAGCCGGTCTTGTCCTCGGGCGAG
ATCCGCTGCATCGGCTCGACCACCTTCCAGGAGTTCCGCGGCATCTTCGAGAAGGACCGGGCCTTGGCGCGGCGCTTCCA
GAAGGTCGACGTGACCGAGCCGTCGGTGGAAGATACCTATGGCATCCTCAAGGGTCTCAAGGGGCGCTTCGAGCAGCATC
ACCACATCGAGTACAGCGACGAGGCGCTGCGCGCCGCGGCCGAGCTGGCGGCGCGCTACATCAACGACCGGCACATGCCG
GACAAGGCCATCGACGTCATCGACGAGGCGGGCGCCTACCAGCGCCTGCAGCCGGAAGAGAAGCGCGTGAAGCGCATCGA
GGTGGCGCAGGTCGAGGATATCGTGGCGAAGATCGCGCGGATCCCGCCGAAACACGTCACCACCTCCGACAAGGAGTTGC
TGCGCAACCTCGAGCGCGAGCTCAAGCTGACCGTGTTCGGCCAGGACGACGCCATCGAGTCGCTGTCCACCGCGATCAAG
CTGTCCCGGGCCGGGCTCAAGGCGCCGGACAAGCCGGTCGGCTCGTTCCTCTTCGCCGGTCCCACCGGCGTGGGCAAGAC
CGAGGTGGCGCGGCAGTTGGCGAAGGCCTTGGGCGTGGAGCTGGTGCGCTTCGACATGTCCGAGTACATGGAGCGGCATA
CCGTGTCGCGGCTGATCGGTGCGCCTCCGGGCTACGTCGGCTTCGACCAGGGCGGCCTGCTCACCGAGGCGATCACCAAG
ACCCCGCACTGCGTGTTGCTGCTCGACGAGATCGAGAAGGCTCACCCGGAGGTCTTCAACCTGCTGCTGCAGGTGATGGA
CCACGGCACCCTGACCGACAACAACGGGCGCAAGGCGGACTTCCGCAACATCATCCTGATCATGACCACCAACGCCGGCG
CGGAAGTGGCGGCGCGCGCGTCGATCGGCTTCAACCAGCAGGATCACACCACCGATGCGATGGAAGTGATCAAGAAGAGC
TTCACCCCGGAGTTCCGCAACCGTCTGGATACCATCATCCAGTTCGGCCGCCTGAGCACCGAGACGATCAAGAGCGTGGT
CGACAAGTTCCTCACCGAGCTGCAGGCGCAGCTGGAGGACAAGCGCGTCCAGCTCGAGGTCAGCGATGCGGCGCGCGGCT
GGCTGGCGGAGAAGGGCTACGACGTGCAGATGGGTGCGCGACCGATGGCGCGGCTTATCCAGGACAAGATCAAGCGGCCG
TTGGCCGAGGAGATCCTGTTCGGCGAGCTGGCCGAGCATGGCGGCCTGGTGCATGTCGACCTGAAGGGCGACGAGCTGGC
CTTCGAGTTCGAGATCACGGCGGCGGAGCTCGCCTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (355-458)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (13-62)

• ATPase family associated with various cellular activities (AAA) (AAA) (216-328)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (658-739)

• AAA domain (Cdc48 subfamily) (AAA_2) (491-652)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	38.956	100	0.423
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.667	96.57	0.402
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	37.374	100	0.391
clpC	Streptococcus mutans UA159	45.645	81.794	0.373
clpC	Lactococcus lactis subsp. cremoris KW2	44.427	82.85	0.368