Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   WX61_RS06975 Genome accession   NZ_CP012028
Coordinates   1303385..1306537 (-) Length   1050 a.a.
NCBI ID   WP_003690520.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 35/02     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1298385..1311537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WX61_RS06950 (WX61_01318) - 1298476..1299039 (-) 564 WP_002214615.1 ComF family protein -
  WX61_RS06955 (WX61_01319) - 1299941..1300330 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  WX61_RS06965 (WX61_01320) - 1300493..1300872 (-) 380 Protein_1313 VOC family protein -
  WX61_RS06970 (WX61_01321) carA 1300926..1302059 (-) 1134 WP_003687283.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  WX61_RS06975 (WX61_01322) pilC 1303385..1306537 (-) 3153 WP_003690520.1 PilC family type IV pilus tip adhesin Machinery gene
  WX61_RS06985 (WX61_01323) apbC 1307946..1309025 (-) 1080 WP_003699443.1 iron-sulfur cluster carrier protein ApbC -
  WX61_RS06995 (WX61_01325) - 1309399..1309908 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  WX61_RS07005 (WX61_01326) nadR 1310249..1310689 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -
  WX61_RS07010 (WX61_01327) hpaC 1310804..1311304 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1050 a.a.        Molecular weight: 115127.37 Da        Isoelectric Point: 9.9739

>NTDB_id=150648 WX61_RS06975 WP_003690520.1 1303385..1306537(-) (pilC) [Neisseria gonorrhoeae strain 35/02]
MNKTLKRRVFRHTALYAAILMFSHTGGGGQAQAQTYKYAIVMNERKQPEVKWKGQYNQSALKDKGRERTFSHTSQKNKFG
ITSNFISFNNNDELVSQQSGTAVFGTATYLPPYGKVSGFDTAELNKRGNAVNWIHTTRPGLAGYGYDGIRCGSAQDCPKL
TYKTRFSFDNPNLVKTRGGLDRHTEPSRENSPIYKLKDHPWLGVSFNLGGEGTAKDGRSSSKLVSSFDENNSNSNQNLVY
TTEGHRISLGNWQRETTAMAYYLNAKLHLLDKKQIENIAPGKTVRLGVLKPSIDVKTQNTGLSGLLNFWSKWDIKDNGQI
PVKLGLPQVKAGRCINKPNPNKNTKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPARPGR
HSLAALDTQNIKSREPNFNSRQTVIRLPGGVYKINPVKNGGRVAGFNGNDGKNDTFGIYKDRLVTPEADEWSEVLLPWTA
RYYGNDDIFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPITAVGGYLATSANDGMVHIFKKTGTDER
SYELKLSYIPGTMERKDIENQDSTLAKELRTFAEKGYVGDRYGVDGGFVLRSITDDQDRQKHFFMFGAMGLGGRGAYALD
LSKIDSNPVGVSMFDVQNESKNNGVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKQIASQENKTALYVYDLGNGSGSLIK
KIEVQGGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSSDKPSEWTVRTIFQGTKPITSAPAVSRLADKRVVIFG
TGSDLSEEDVVGKDQQYIYGIFDDDKGTGTVKVTVQNGTGGGLLEQTLTKENNTLFLSNNKASGGSNGKGWVVRLREGER
VTVKPTVVLRTAFVTIRSYTGNDKCGAQTAILGINTADGGALTPRSARPIVPDHDSVAQYSGHKKTADGKSVPIGCMWKN
GKTACPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGI
KRLSWREVFF

Nucleotide


Download         Length: 3153 bp        

>NTDB_id=150648 WX61_RS06975 WP_003690520.1 1303385..1306537(-) (pilC) [Neisseria gonorrhoeae strain 35/02]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGCAGGCGCAGGCGCAAACGTATAAATACGCTATTGTGATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGAAGG
GTCAATATAATCAATCAGCATTAAAGGACAAAGGCAGGGAGCGGACATTTAGCCATACGAGCCAGAAAAACAAATTCGGC
ATCACAAGCAATTTTATCTCATTCAACAATAACGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGC
CACCTACCTGCCGCCCTACGGCAAGGTTTCCGGCTTTGATACCGCCGAGCTGAACAAGCGCGGCAATGCCGTCAATTGGA
TTCATACCACCCGGCCCGGGCTGGCAGGCTACGGCTACGACGGTATCCGTTGCGGAAGTGCCCAAGACTGTCCCAAACTT
ACCTATAAAACCCGATTTTCCTTCGATAATCCCAACTTGGTAAAAACAAGAGGCGGGCTGGATAGGCACACAGAGCCAAG
CCGCGAAAATTCGCCCATTTACAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGGCGAGGGTACCG
CCAAAGATGGCAGATCATCCAGCAAATTGGTATCTTCTTTTGATGAAAACAATAGTAATAGTAATCAAAACCTCGTCTAT
ACGACAGAAGGCCACCGTATTTCCCTTGGCAACTGGCAGCGCGAAACGACCGCCATGGCCTATTATCTGAACGCCAAGCT
GCACCTGCTGGACAAAAAACAGATTGAAAATATCGCGCCAGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCG
ATGTGAAGACACAAAATACGGGGCTTAGCGGCTTGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATT
CCGGTCAAGCTCGGCCTGCCGCAAGTCAAAGCAGGCCGCTGCATCAATAAACCGAACCCCAATAAGAATACCAAAGCCCC
TTCGCCGGCCCTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTT
CTACCTACCCCGGCAGTTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGCCCGGCCCGGCCGG
CATTCCCTCGCCGCTTTGGATACGCAGAACATCAAAAGCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTGATCCGATT
GCCGGGCGGCGTGTACAAGATCAACCCGGTCAAGAACGGCGGCCGGGTCGCGGGTTTTAATGGCAATGACGGCAAAAACG
ACACTTTCGGCATCTACAAGGACAGGCTCGTCACACCTGAGGCCGACGAGTGGAGCGAAGTGCTGCTGCCTTGGACGGCT
CGGTATTACGGTAATGACGATATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAG
CCAAAAATACCGCATCCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATAA
CGGCGGTCGGCGGGTATCTGGCAACTTCTGCCAACGACGGGATGGTGCATATCTTCAAAAAAACCGGCACGGATGAACGC
AGCTACGAACTGAAGCTCAGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAAACCAAGACTCCACCCTCGCCAA
AGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCAGCATTA
CAGATGACCAAGACAGGCAAAAACATTTCTTTATGTTCGGCGCAATGGGCCTTGGCGGCAGAGGCGCATACGCCTTGGAT
TTAAGCAAAATCGACAGCAACCCGGTCGGCGTTTCCATGTTTGATGTCCAAAACGAGAGTAAAAATAATGGCGTGAAATT
AGGCTACACCGTCGGTACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGG
CTAAACAAATTGCCAGCCAAGAAAATAAAACCGCGCTGTATGTGTATGATTTGGGAAACGGCAGTGGTAGTCTGATTAAA
AAAATCGAAGTGCAGGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTCGATAT
CGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGATTTGAGCAGCGACAAGCCGTCCGAGTGGACTGTACGCA
CTATTTTCCAAGGCACAAAACCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTGGTTATCTTCGGC
ACGGGCAGCGATTTGAGTGAAGAGGATGTAGTCGGTAAGGATCAACAATATATTTACGGTATCTTTGACGACGATAAGGG
GACGGGGACGGTTAAGGTAACGGTACAAAACGGCACGGGAGGCGGGCTGCTCGAGCAAACGCTTACGAAGGAAAATAACA
CCTTGTTCCTGAGCAATAATAAGGCATCCGGCGGATCGAACGGCAAAGGGTGGGTAGTGAGATTGAGGGAAGGAGAACGC
GTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTCACCATCCGTAGCTATACGGGTAATGACAAATGCGGCGC
GCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGATC
ACGATTCGGTTGCGCAATATTCCGGCCATAAGAAAACCGCCGACGGCAAGTCCGTCCCTATAGGCTGTATGTGGAAAAAC
GGCAAAACCGCCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGACGA
TTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGT
GCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATC
AAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(525-861)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

70.066

100

0.707

Multiple sequence alignment