Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   WX60_RS09660 Genome accession   NZ_CP012027
Coordinates   1779488..1782634 (-) Length   1048 a.a.
NCBI ID   WP_082299271.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain FA6140     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1765315..1785091 1779488..1782634 within 0


Gene organization within MGE regions


Location: 1765315..1785091
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WX60_RS09595 (WX60_01822) orn 1765694..1766257 (-) 564 WP_003687260.1 oligoribonuclease -
  WX60_RS09600 (WX60_01823) prmA 1766275..1767162 (-) 888 WP_003696642.1 50S ribosomal protein L11 methyltransferase -
  WX60_RS09605 (WX60_01824) accC 1767266..1768627 (-) 1362 WP_003687264.1 acetyl-CoA carboxylase biotin carboxylase subunit -
  WX60_RS09610 (WX60_01825) accB 1768741..1769160 (-) 420 WP_003690508.1 acetyl-CoA carboxylase biotin carboxyl carrier protein -
  WX60_RS09615 - 1769142..1769399 (-) 258 WP_003687268.1 hypothetical protein -
  WX60_RS09620 (WX60_01826) queA 1769516..1770556 (+) 1041 WP_003687270.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  WX60_RS09625 (WX60_01827) carB 1770757..1773972 (-) 3216 WP_003690509.1 carbamoyl-phosphate synthase large subunit -
  WX60_RS09630 (WX60_01828) - 1773983..1774516 (-) 534 WP_003692498.1 hypothetical protein -
  WX60_RS09635 (WX60_01829) - 1775520..1775909 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  WX60_RS09645 (WX60_01830) - 1776072..1776451 (-) 380 Protein_1807 VOC family protein -
  WX60_RS09650 (WX60_01831) carA 1776505..1777638 (-) 1134 WP_025455926.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  WX60_RS09655 (WX60_01832) - 1778353..1778637 (-) 285 WP_003692093.1 GIY-YIG nuclease family protein -
  WX60_RS09660 (WX60_01833) pilC 1779488..1782634 (-) 3147 WP_082299271.1 PilC family type IV pilus tip adhesin Machinery gene

Sequence

Protein


Download         Length: 1048 a.a.        Molecular weight: 114637.96 Da        Isoelectric Point: 9.9767

>NTDB_id=150611 WX60_RS09660 WP_082299271.1 1779488..1782634(-) (pilC) [Neisseria gonorrhoeae strain FA6140]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGAQAQTREYAIIMNERNQPEVKWEGSYSTLREKDRKREYTHHKYPRGGSSV
SFNNNDELVSQQSGTAVFGTATYLPPYGKVSGFDTDSLKGRANAVDWIRTTRIALAGYSYAGVVCNSTTGCPKLVYKTRF
SFDNPDLAKTGGRLNRHTEPSRDNSPIYKLKDYPWLGVSFNLGAEGTAKDGKVTNKLVSSFDENNSNQNLVYTTEGHNIS
LGNWQRESTAMAYYLNAKLHLLDKKGIKDITSKTVRLGVLKPSIDVRKGNTGLSGILSFWATWDIKDTGQIPVKLGLPQV
KAGRCINKPNPNNNTKAPSPALTAPALWFGPGQDGKVQMYSASVSTYPGSSSSRIFLQELKTKTDPGRPGRHSLAALNTQ
DIKSREPNFNSRQTVIRLPGGVYKINSGKNGGRVAGINGNDGKNDTFGIFKDRLVTPVADEWSEVLLPWTARYYGNDDIF
KTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPIVAVDGYLATSANDGMVHIFKKNGGSDERSYNLKLSY
IPGTMPRQYFDNDTSALKDSTLAQELRTFAEKGYVGDRYGVDGGFVLRRITDDQDRQKHFFMFGAMGLGGRGAYALDLTK
IDSNPVGVSMFDVQNDKNNNNRVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKQIASQENKTALYVYDLGNGSGSLIKKI
EVQGGKGGLSSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSDNDPNKWSVRTIFEGGKPITSAPAVSRLADKRVVIFGTG
SDLSEEDVVDTKEQYIYGIFDDDKGTGTVKVTVQNGTGGGLLKQTLTKESKTLFLSNNKASGGSADKGWVVKLREGERVT
VKPTVVLRTAFVTIRSYTGNDKCGAQTAILGINTADGGALTPRSARPIVPDHNSVAQYSGHKKTSKGKSIPIGCMEKGGK
TVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGIKR
LSWREVFF

Nucleotide


Download         Length: 3147 bp        

>NTDB_id=150611 WX60_RS09660 WP_082299271.1 1779488..1782634(-) (pilC) [Neisseria gonorrhoeae strain FA6140]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGCAGGCGCAAACCCGTGAATACGCTATTATCATGAACGAACGAAATCAGCCGGAGGTAAAGTGGGAGG
GTTCATATTCAACCTTAAGGGAAAAAGACAGGAAGCGCGAATATACTCATCATAAGTACCCACGAGGAGGAAGCTCTGTC
TCATTCAACAATAACGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTA
CGGCAAGGTTTCCGGTTTTGATACCGATAGTCTGAAAGGGCGCGCCAATGCCGTTGATTGGATTCGTACCACCCGCATCG
CGCTGGCAGGCTACAGCTACGCCGGTGTCGTATGCAACAGCACCACAGGCTGTCCCAAACTTGTCTATAAAACCCGATTT
TCCTTCGATAATCCCGACTTGGCAAAAACAGGAGGCAGGCTGAATAGGCACACAGAGCCAAGCCGCGACAATTCGCCCAT
TTACAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTACCGCCAAAGATGGTAAGGTAA
CCAACAAATTGGTATCTTCTTTTGATGAAAACAATAGTAATCAAAACCTCGTCTATACCACGGAAGGCCACAATATTTCC
TTGGGCAACTGGCAGCGCGAAAGTACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAGGGAT
TAAAGATATCACCAGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGCGGAAAGGAAATACGGGGCTTA
GCGGCATTCTATCTTTTTGGGCTACGTGGGACATTAAAGATACCGGGCAGATTCCGGTCAAGCTCGGCCTGCCGCAAGTC
AAAGCAGGCCGCTGCATCAACAAACCGAACCCCAATAATAATACCAAAGCCCCTTCGCCGGCACTGACCGCCCCCGCGCT
GTGGTTCGGACCCGGGCAAGATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCTACCTACCCCGGCAGCTCGAGCAGCC
GCATCTTCCTCCAAGAGCTGAAAACTAAAACCGACCCCGGCAGGCCCGGCCGGCATTCCCTCGCCGCTTTGAATACGCAG
GATATCAAATCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTCATCCGATTGCCGGGCGGCGTGTACAAGATCAACTC
GGGCAAGAACGGCGGCCGGGTCGCGGGTATTAATGGCAATGACGGCAAAAACGACACTTTCGGCATCTTCAAGGACAGGC
TCGTCACACCTGTGGCCGACGAGTGGAGCGAAGTGCTGCTGCCTTGGACGGCCCGGTATTACGGTAATGACGATATATTT
AAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAGCCAAAAATACCGCATCCGCACAAAAGA
AGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATTGTCGCGGTCGACGGGTATTTGGCAACTT
CTGCCAACGACGGGATGGTGCATATCTTCAAAAAAAACGGCGGCAGTGATGAACGCAGCTACAATCTGAAGCTCAGCTAC
ATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGACACTTCCGCTCTCAAAGACTCCACCCTCGCCCAAGAGCTGCG
CACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACC
AGGACAGGCAAAAACATTTCTTTATGTTCGGCGCAATGGGCCTTGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAA
ATCGACAGCAACCCGGTCGGCGTTTCCATGTTTGATGTCCAAAACGACAAAAATAACAATAATCGCGTGAAATTAGGCTA
CACCGTCGGCACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGGCTAAAC
AAATTGCCAGCCAAGAAAATAAAACCGCGCTGTATGTGTATGATTTGGGAAACGGCAGTGGTAGTCTGATTAAAAAAATC
GAAGTGCAGGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTA
TGCCGGCGACCGGGGCGGGAATATGTACCGCTTTGATTTGAGCGACAACGACCCGAACAAATGGTCTGTACGCACTATTT
TCGAAGGCGGGAAGCCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTCGTCATCTTCGGTACGGGC
AGCGATTTGAGTGAAGAGGATGTAGTCGATACGAAAGAACAATATATTTACGGTATCTTCGACGACGATAAGGGGACGGG
GACGGTTAAGGTAACGGTACAAAACGGCACGGGAGGCGGGCTGCTCAAGCAAACGCTTACGAAGGAAAGTAAAACCTTGT
TCCTGAGCAATAATAAGGCATCCGGCGGATCGGCCGATAAAGGCTGGGTAGTGAAATTGAGGGAAGGAGAACGCGTTACC
GTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTCACCATCCGCAGCTATACGGGTAATGACAAATGCGGCGCGCAAAC
CGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGATCACAATT
CGGTTGCGCAATATTCCGGCCATAAGAAAACCTCCAAAGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGGCGGTAAA
ACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGACGATTTCCC
CGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCT
CCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATCAAACGC
TTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(530-859)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

70.916

100

0.717

Multiple sequence alignment