Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   ACJ67_RS13175 Genome accession   NZ_CP012020
Coordinates   2784661..2786151 (+) Length   496 a.a.
NCBI ID   WP_049639462.1    Uniprot ID   A0A0K0SYH7
Organism   Methylophilus sp. TWE2     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2779661..2791151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJ67_RS13150 (ACJ67_13150) pbpG 2780102..2781175 (+) 1074 WP_049639459.1 D-alanyl-D-alanine endopeptidase -
  ACJ67_RS13155 (ACJ67_13155) - 2781254..2781760 (-) 507 WP_197080721.1 DUF3106 domain-containing protein -
  ACJ67_RS13160 (ACJ67_13160) - 2781821..2782192 (-) 372 WP_049639460.1 DUF3619 family protein -
  ACJ67_RS13165 (ACJ67_13165) - 2782197..2782772 (-) 576 WP_049639953.1 RNA polymerase sigma factor -
  ACJ67_RS13170 (ACJ67_13170) - 2783063..2784658 (+) 1596 WP_049639461.1 nitrogen regulation protein NR(II) -
  ACJ67_RS13175 (ACJ67_13175) pilR 2784661..2786151 (+) 1491 WP_049639462.1 sigma-54 dependent transcriptional regulator Regulator
  ACJ67_RS13180 (ACJ67_13180) - 2786192..2787202 (-) 1011 WP_049639463.1 sodium:calcium antiporter -
  ACJ67_RS13185 (ACJ67_13185) ampD 2787329..2787877 (+) 549 WP_049639464.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  ACJ67_RS13190 (ACJ67_13190) - 2787874..2789022 (+) 1149 WP_049639465.1 efflux RND transporter periplasmic adaptor subunit -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 54348.27 Da        Isoelectric Point: 4.7318

>NTDB_id=150430 ACJ67_RS13175 WP_049639462.1 2784661..2786151(+) (pilR) [Methylophilus sp. TWE2]
MANSYRCLVVDDETDIRELVVLTLERMGIQAESASSVTDAKHMLNSFSYDLCLTDMRLPDGLGLELVQHINAQFPGLPVA
VITAYGSAENAVSALKAGAYDYITKPISLKQLRPLVESALKLSSQKETQGANTVDLIGASPVMSYVRTMIAKLARSQAPV
YISGESGSGKELAARLIHLNSSRKEQSFIAVNCGAIPENLMESEFFGYKKGAFTGAIQDTLGLFQAANGGTLFLDEVADL
PLAMQVKLLRAIQEKKVRVVGSTSEEAVDVRIISATHKNLNAMMEKGEFRQDLYYRLNVIQLKMPSLRERPEDIPELTER
LLAKLCQAQGIAMPAISDEAKVYIQQLPFHGNVRELENMLERALALCDGVSITVEDLSLDEIRINLADKPVLPWNAPVTE
PSVMTSTISEPGLPAPTTTSPSHGSTMLPMDISLSDYLEDIEKRTILQALEKTNNNKTAAAKLLGISFRTLRYRLSKLGL
SKEQDPDLEESDGDEE

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=150430 ACJ67_RS13175 WP_049639462.1 2784661..2786151(+) (pilR) [Methylophilus sp. TWE2]
ATGGCAAACTCATATCGTTGTCTGGTGGTTGATGACGAAACCGATATTCGCGAACTGGTAGTACTGACACTGGAGCGCAT
GGGCATACAAGCAGAGAGTGCCAGTTCGGTCACCGATGCAAAACACATGCTGAATTCGTTCAGCTACGACTTGTGCCTTA
CTGATATGCGCCTGCCGGATGGGCTGGGGCTGGAGCTGGTACAACATATTAACGCGCAATTTCCCGGATTACCGGTGGCG
GTCATCACCGCTTATGGCAGTGCCGAGAATGCAGTGTCAGCACTTAAGGCTGGCGCTTATGACTACATTACCAAGCCAAT
TTCACTCAAACAATTGCGGCCCCTGGTAGAGTCCGCACTCAAACTGTCGTCGCAAAAAGAAACGCAAGGGGCCAATACAG
TCGATCTGATTGGTGCGTCACCGGTCATGAGCTATGTGCGCACCATGATTGCAAAACTGGCGCGCAGCCAGGCACCCGTG
TATATCAGCGGTGAATCTGGCAGTGGCAAGGAATTGGCGGCCAGACTCATCCACCTCAACAGCTCACGCAAAGAACAGTC
TTTTATTGCCGTGAACTGCGGCGCCATCCCGGAAAACTTGATGGAAAGCGAGTTCTTTGGCTATAAGAAAGGGGCATTTA
CTGGCGCCATCCAGGATACCCTCGGCCTATTCCAGGCAGCCAATGGCGGCACCTTGTTTCTGGATGAAGTCGCGGATCTC
CCGCTGGCCATGCAAGTTAAGCTGCTGCGTGCCATCCAGGAGAAAAAAGTACGCGTGGTCGGCAGTACCAGTGAAGAAGC
CGTGGATGTGCGTATTATTTCTGCCACGCACAAGAACCTCAATGCCATGATGGAAAAAGGCGAGTTCCGGCAAGATTTGT
ATTACCGTCTGAATGTGATTCAACTCAAAATGCCGTCTTTGCGTGAACGGCCTGAAGACATTCCCGAACTGACTGAACGC
CTGCTCGCCAAACTGTGCCAGGCACAGGGCATTGCTATGCCCGCTATCTCCGATGAAGCCAAGGTCTATATCCAGCAGCT
ACCTTTCCACGGCAATGTGCGTGAACTGGAAAATATGCTGGAACGTGCCCTAGCCTTGTGTGACGGCGTCAGCATTACGG
TTGAAGACCTGTCGCTCGATGAAATACGTATAAATTTAGCTGACAAGCCGGTATTGCCATGGAATGCACCTGTCACCGAG
CCATCGGTCATGACCAGCACCATTAGCGAACCTGGCCTGCCAGCACCAACCACAACCAGCCCATCTCACGGTAGCACCAT
GTTGCCCATGGATATCAGCCTGTCTGACTATCTGGAAGATATTGAAAAGCGCACGATTTTGCAGGCGCTGGAAAAAACCA
ATAATAACAAGACCGCTGCGGCAAAACTGTTAGGGATTAGCTTCCGTACTTTGCGCTACCGTTTGTCTAAGTTGGGCTTA
TCCAAAGAGCAGGACCCTGATCTCGAAGAGAGTGATGGAGATGAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(8-114)

Bacterial regulatory protein, Fis family (HTH_8)

(438-478)

Sigma-54 interaction domain (Sigma54_activat)

(136-302)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K0SYH7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

54.737

95.766

0.524
  pilR Acinetobacter baumannii strain A118

45.773

97.782

0.448

Multiple sequence alignment