Detailed information NTG0150313

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: SAGV51_RS08965
• Genome accession: NZ_CP012015
• Coordinates: 1780642..1781328 (-)
• Length: 228 a.a.
• NCBI ID: WP_001792568.1
• Uniprot ID: A0A133PXY3
• Organism: Staphylococcus aureus strain Gv51
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1775642..1786328

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAGV51_RS08945 (SAGV51_03681)	rpsT	1776556..1776807 (+)	252	WP_001274017.1	30S ribosomal protein S20	-
SAGV51_RS08950 (SAGV51_01859)	holA	1776852..1777826 (-)	975	WP_001282562.1	DNA polymerase III subunit delta	-
SAGV51_RS08955 (SAGV51_03682)	comEC	1777883..1780084 (-)	2202	WP_001807336.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SAGV51_RS08960 (SAGV51_01861)	-	1780089..1780550 (-)	462	WP_000439693.1	ComE operon protein 2	-
SAGV51_RS08965 (SAGV51_03683)	comEA	1780642..1781328 (-)	687	WP_001792568.1	ComEA family DNA-binding protein	Machinery gene
SAGV51_RS08970 (SAGV51_04036)	-	1781368..1782083 (-)	716	Protein_1743	class I SAM-dependent DNA methyltransferase	-
SAGV51_RS08975 (SAGV51_01865)	rsfS	1782086..1782439 (-)	354	WP_001088022.1	ribosome silencing factor	-
SAGV51_RS08980 (SAGV51_01866)	yqeK	1782440..1783024 (-)	585	WP_001019324.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
SAGV51_RS08985 (SAGV51_01867)	nadD	1783014..1783583 (-)	570	WP_000725162.1	nicotinate (nicotinamide) nucleotide adenylyltransferase	-
SAGV51_RS08990 (SAGV51_01868)	yhbY	1783586..1783876 (-)	291	WP_000955231.1	ribosome assembly RNA-binding protein YhbY	-
SAGV51_RS08995 (SAGV51_03684)	aroE	1783880..1784686 (-)	807	WP_000666761.1	shikimate dehydrogenase	-
SAGV51_RS09000 (SAGV51_01870)	yqeH	1784700..1785800 (-)	1101	WP_001280141.1	ribosome biogenesis GTPase YqeH	-
SAGV51_RS09005 (SAGV51_01871)	-	1785801..1786328 (-)	528	WP_000524902.1	YqeG family HAD IIIA-type phosphatase	-

Sequence

Protein

• Length: 228 a.a.
• Molecular weight: 25863.49 Da
• Isoelectric Point: 9.3305

>NTDB_id=150313 SAGV51_RS08965 WP_001792568.1 1780642..1781328(-) (comEA) [Staphylococcus aureus strain Gv51]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide

• Length: 687 bp

>NTDB_id=150313 SAGV51_RS08965 WP_001792568.1 1780642..1781328(-) (comEA) [Staphylococcus aureus strain Gv51]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (164-227)

3D structure

• AlphaFold DB: A0A133PXY3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Staphylococcus aureus MW2	98.238	99.561	0.978
comEA	Staphylococcus aureus N315	97.357	99.561	0.969