Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | SAHC1335_RS06775 | Genome accession | NZ_CP012012 |
| Coordinates | 1341069..1341941 (+) | Length | 290 a.a. |
| NCBI ID | WP_000593192.1 | Uniprot ID | A0A140HKN1 |
| Organism | Staphylococcus aureus strain HC1335 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1306313..1351927 | 1341069..1341941 | within | 0 |
Gene organization within MGE regions
Location: 1306313..1351927
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SAHC1335_RS06615 (SAHC1335_02150) | - | 1306759..1307502 (+) | 744 | WP_000888494.1 | protein-serine/threonine phosphatase Stp1 | - |
| SAHC1335_RS06620 (SAHC1335_02151) | pknB | 1307499..1309493 (+) | 1995 | WP_000579564.1 | serine/threonine protein kinase Stk1 | - |
| SAHC1335_RS06625 (SAHC1335_02152) | rsgA | 1309721..1310597 (+) | 877 | Protein_1289 | ribosome small subunit-dependent GTPase A | - |
| SAHC1335_RS06630 (SAHC1335_02153) | rpe | 1310598..1311242 (+) | 645 | WP_000164332.1 | ribulose-phosphate 3-epimerase | - |
| SAHC1335_RS06635 (SAHC1335_03543) | - | 1311249..1311890 (+) | 642 | WP_000547905.1 | thiamine diphosphokinase | - |
| SAHC1335_RS06640 (SAHC1335_02155) | rpmB | 1312271..1312459 (-) | 189 | WP_000517908.1 | 50S ribosomal protein L28 | - |
| SAHC1335_RS06645 (SAHC1335_02157) | - | 1312902..1313276 (+) | 375 | WP_000171418.1 | Asp23/Gls24 family envelope stress response protein | - |
| SAHC1335_RS06650 (SAHC1335_02158) | fakA | 1313291..1314937 (+) | 1647 | WP_020444702.1 | fatty acid kinase catalytic subunit FakA | - |
| SAHC1335_RS06655 (SAHC1335_02159) | recG | 1315126..1317186 (+) | 2061 | WP_001151499.1 | ATP-dependent DNA helicase RecG | - |
| SAHC1335_RS06660 (SAHC1335_03544) | fapR | 1317389..1317961 (+) | 573 | WP_001548538.1 | transcription factor FapR | - |
| SAHC1335_RS06665 (SAHC1335_02161) | plsX | 1317966..1318952 (+) | 987 | WP_000239744.1 | phosphate acyltransferase PlsX | - |
| SAHC1335_RS06670 (SAHC1335_02162) | fabD | 1318945..1319871 (+) | 927 | WP_000047348.1 | ACP S-malonyltransferase | - |
| SAHC1335_RS06675 (SAHC1335_02163) | fabG | 1319864..1320598 (+) | 735 | WP_000167269.1 | 3-oxoacyl-[acyl-carrier-protein] reductase | - |
| SAHC1335_RS06685 (SAHC1335_02164) | - | 1320841..1321074 (+) | 234 | WP_000426914.1 | acyl carrier protein | - |
| SAHC1335_RS06690 (SAHC1335_02165) | rnc | 1321190..1321921 (+) | 732 | WP_000043237.1 | ribonuclease III | - |
| SAHC1335_RS06695 (SAHC1335_02166) | smc | 1322068..1325634 (+) | 3567 | WP_000262704.1 | chromosome segregation protein SMC | - |
| SAHC1335_RS06700 (SAHC1335_02167) | ftsY | 1325634..1326884 (+) | 1251 | WP_000007683.1 | signal recognition particle-docking protein FtsY | - |
| SAHC1335_RS06705 (SAHC1335_02168) | - | 1326871..1327203 (+) | 333 | WP_000531320.1 | putative DNA-binding protein | - |
| SAHC1335_RS06710 (SAHC1335_02169) | ffh | 1327229..1328596 (+) | 1368 | WP_000863479.1 | signal recognition particle protein | - |
| SAHC1335_RS06715 (SAHC1335_02171) | rpsP | 1329031..1329306 (+) | 276 | WP_000268754.1 | 30S ribosomal protein S16 | - |
| SAHC1335_RS06720 (SAHC1335_02172) | rimM | 1329494..1329997 (+) | 504 | WP_001261987.1 | ribosome maturation factor RimM | - |
| SAHC1335_RS06725 (SAHC1335_02173) | trmD | 1329997..1330734 (+) | 738 | WP_000687328.1 | tRNA (guanosine(37)-N1)-methyltransferase TrmD | - |
| SAHC1335_RS06730 (SAHC1335_02174) | rplS | 1330837..1331187 (+) | 351 | WP_000181404.1 | 50S ribosomal protein L19 | - |
| SAHC1335_RS06740 (SAHC1335_03546) | yfhO | 1331431..1334037 (-) | 2607 | WP_000915229.1 | lipoteichoic acid-specific glycosyltransferase YfhO | - |
| SAHC1335_RS06745 (SAHC1335_02176) | ylqF | 1334438..1335322 (+) | 885 | WP_000236722.1 | ribosome biogenesis GTPase YlqF | - |
| SAHC1335_RS06750 (SAHC1335_02177) | - | 1335306..1336073 (+) | 768 | WP_000176394.1 | ribonuclease HII | - |
| SAHC1335_RS06755 (SAHC1335_02178) | sucC | 1336182..1337349 (+) | 1168 | Protein_1313 | ADP-forming succinate--CoA ligase subunit beta | - |
| SAHC1335_RS06760 (SAHC1335_02179) | sucD | 1337371..1338279 (+) | 909 | WP_000110247.1 | succinate--CoA ligase subunit alpha | - |
| SAHC1335_RS06765 (SAHC1335_02180) | - | 1338506..1339624 (+) | 1119 | WP_041205375.1 | LysM peptidoglycan-binding domain-containing protein | - |
| SAHC1335_RS06770 (SAHC1335_02181) | fmhC | 1339652..1340896 (+) | 1245 | WP_000672867.1 | FemA/FemB family glycyltransferase FmhC | - |
| SAHC1335_RS06775 (SAHC1335_03547) | dprA | 1341069..1341941 (+) | 873 | WP_000593192.1 | DNA-processing protein DprA | Machinery gene |
| SAHC1335_RS06780 (SAHC1335_02183) | topA | 1342115..1344190 (+) | 2076 | WP_001548566.1 | type I DNA topoisomerase | - |
| SAHC1335_RS06785 (SAHC1335_02184) | trmFO | 1344346..1345653 (+) | 1308 | WP_000195254.1 | methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO | - |
| SAHC1335_RS06790 (SAHC1335_02185) | xerC | 1346070..1346966 (+) | 897 | WP_001015597.1 | tyrosine recombinase XerC | - |
| SAHC1335_RS06795 (SAHC1335_02186) | hslV | 1346963..1347508 (+) | 546 | WP_000072681.1 | ATP-dependent protease subunit HslV | - |
| SAHC1335_RS06800 (SAHC1335_02187) | hslU | 1347574..1348977 (+) | 1404 | WP_000379054.1 | ATP-dependent protease ATPase subunit HslU | - |
| SAHC1335_RS06805 (SAHC1335_02188) | codY | 1349002..1349775 (+) | 774 | WP_000055337.1 | GTP-sensing pleiotropic transcriptional regulator CodY | - |
| SAHC1335_RS06810 | - | 1349826..1349918 (+) | 93 | WP_001790530.1 | hypothetical protein | - |
| SAHC1335_RS06815 (SAHC1335_02190) | rpsB | 1350117..1350884 (+) | 768 | WP_000268484.1 | 30S ribosomal protein S2 | - |
| SAHC1335_RS06820 | - | 1350918..1351031 (+) | 114 | WP_001789890.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 290 a.a. Molecular weight: 33564.99 Da Isoelectric Point: 9.5094
>NTDB_id=150216 SAHC1335_RS06775 WP_000593192.1 1341069..1341941(+) (dprA) [Staphylococcus aureus strain HC1335]
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
Nucleotide
Download Length: 873 bp
>NTDB_id=150216 SAHC1335_RS06775 WP_000593192.1 1341069..1341941(+) (dprA) [Staphylococcus aureus strain HC1335]
TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCTGAATATCCACCACATACACCAATCGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA
TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCTGAATATCCACCACATACACCAATCGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Staphylococcus aureus MW2 |
100 |
100 |
1 |
| dprA | Staphylococcus aureus N315 |
99.655 |
100 |
0.997 |