Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SAHC1340_RS11165 Genome accession   NZ_CP012011
Coordinates   2167830..2168459 (-) Length   209 a.a.
NCBI ID   WP_000153530.1    Uniprot ID   D9IFM7
Organism   Staphylococcus aureus strain HC1340     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2162830..2173459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAHC1340_RS11140 (SAHC1340_02866) - 2163794..2163982 (-) 189 WP_374700838.1 DUF1128 domain-containing protein -
  SAHC1340_RS11145 - 2164027..2165199 (-) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  SAHC1340_RS11150 (SAHC1340_02868) - 2165473..2165937 (+) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  SAHC1340_RS11155 (SAHC1340_02869) - 2165944..2166219 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  SAHC1340_RS11160 (SAHC1340_02871) - 2166497..2167714 (+) 1218 WP_000037075.1 YihY/virulence factor BrkB family protein -
  SAHC1340_RS11165 (SAHC1340_02872) vraR 2167830..2168459 (-) 630 WP_000153530.1 two-component system response regulator VraR Regulator
  SAHC1340_RS11170 (SAHC1340_02873) vraS 2168449..2169492 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  SAHC1340_RS11175 (SAHC1340_02874) liaF 2169489..2170190 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  SAHC1340_RS11180 (SAHC1340_02875) - 2170205..2170591 (-) 387 WP_001110179.1 hypothetical protein -
  SAHC1340_RS11185 (SAHC1340_02876) map 2170808..2171566 (-) 759 WP_000636142.1 type I methionyl aminopeptidase -
  SAHC1340_RS11190 (SAHC1340_02877) - 2172038..2173024 (+) 987 WP_000999713.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23545.29 Da        Isoelectric Point: 5.3889

>NTDB_id=150194 SAHC1340_RS11165 WP_000153530.1 2167830..2168459(-) (vraR) [Staphylococcus aureus strain HC1340]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=150194 SAHC1340_RS11165 WP_000153530.1 2167830..2168459(-) (vraR) [Staphylococcus aureus strain HC1340]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGATGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D9IFM7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.522

100

0.995
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment