Detailed information NTG0149144

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: ABU16_RS01945
• Genome accession: NZ_CP011882
• Coordinates: 384981..386138 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain TO-A JPC
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 379981..391138

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABU16_RS01915 (ABU16_0394)	yvyF	380234..380653 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
ABU16_RS01920 (ABU16_0395)	comFC	380727..381449 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
ABU16_RS01925 (ABU16_0396)	comFB	381413..381709 (-)	297	WP_003227989.1	late competence protein ComFB	-
ABU16_RS01930 (ABU16_0397)	comFA	381769..383160 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
ABU16_RS01935 (ABU16_0398)	fakBA	383266..384111 (-)	846	WP_003244125.1	DegV family protein	-
ABU16_RS01940 (ABU16_0399)	degU	384209..384898 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
ABU16_RS01945 (ABU16_0400)	degS	384981..386138 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
ABU16_RS01950 (ABU16_0401)	yvyE	386355..387008 (+)	654	WP_003227979.1	YigZ family protein	-
ABU16_RS01955 (ABU16_0402)	tagV	387008..388183 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
ABU16_RS01960 (ABU16_0403)	tagO	388256..389332 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
ABU16_RS01965 (ABU16_0404)	tuaH	389477..390670 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=149144 ABU16_RS01945 WP_003227983.1 384981..386138(-) (degS) [Bacillus subtilis strain TO-A JPC]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=149144 ABU16_RS01945 WP_003227983.1 384981..386138(-) (degS) [Bacillus subtilis strain TO-A JPC]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1