Detailed information NTG0146818

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ABO05_RS05995
• Genome accession: NZ_CP011535
• Coordinates: 1185929..1187158 (-)
• Length: 409 a.a.
• NCBI ID: WP_047298102.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain M28PF1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1180929..1192158

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABO05_RS05975 (ABO05_05980)	rpiA	1181211..1181894 (-)	684	WP_011284704.1	ribose-5-phosphate isomerase RpiA	-
ABO05_RS05980 (ABO05_05985)	-	1182272..1184371 (+)	2100	WP_011284703.1	AAA family ATPase	-
ABO05_RS05985 (ABO05_05990)	-	1184429..1185172 (-)	744	WP_002984942.1	hypothetical protein	-
ABO05_RS05990 (ABO05_05995)	yihA	1185320..1185919 (-)	600	WP_011284702.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ABO05_RS05995 (ABO05_06000)	clpX	1185929..1187158 (-)	1230	WP_047298102.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ABO05_RS10140 (ABO05_06005)	-	1187288..1187458 (-)	171	WP_002990165.1	hypothetical protein	-
ABO05_RS06000 (ABO05_06010)	-	1187478..1187975 (-)	498	WP_011284701.1	dihydrofolate reductase	-
ABO05_RS06005 (ABO05_06015)	-	1188055..1188894 (-)	840	WP_011017679.1	thymidylate synthase	-
ABO05_RS06010 (ABO05_06020)	-	1189103..1190278 (+)	1176	WP_021340971.1	hydroxymethylglutaryl-CoA synthase	-
ABO05_RS06015 (ABO05_06025)	-	1190265..1191542 (+)	1278	WP_011284699.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45021.46 Da
• Isoelectric Point: 4.5775

>NTDB_id=146818 ABO05_RS05995 WP_047298102.1 1185929..1187158(-) (clpX) [Streptococcus pyogenes strain M28PF1]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFTIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=146818 ABO05_RS05995 WP_047298102.1 1185929..1187158(-) (clpX) [Streptococcus pyogenes strain M28PF1]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTACTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAGCGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.354	98.044	0.572