Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   AA973_RS00095 Genome accession   NZ_CP011485
Coordinates   12006..14369 (+) Length   787 a.a.
NCBI ID   WP_064437111.1    Uniprot ID   -
Organism   Helicobacter pylori strain ausabrJ05     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 7006..19369
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA973_RS00065 (AA973_00065) groES 7036..7392 (-) 357 WP_064437107.1 co-chaperone GroES -
  AA973_RS00070 (AA973_00070) dnaG 7668..9347 (+) 1680 WP_064437108.1 DNA primase -
  AA973_RS00075 (AA973_00075) - 9344..10396 (+) 1053 WP_064437109.1 MnmA/TRMU family protein -
  AA973_RS00080 (AA973_00080) - 10487..11314 (+) 828 WP_064437110.1 DUF5718 family protein -
  AA973_RS00085 (AA973_00085) comB2 11460..11741 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  AA973_RS00090 (AA973_00090) comB3 11741..12004 (+) 264 WP_000584956.1 hypothetical protein Machinery gene
  AA973_RS00095 (AA973_00095) comB4 12006..14369 (+) 2364 WP_064437111.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  AA973_RS00105 (AA973_00100) - 14696..16036 (+) 1341 WP_064437112.1 COG3014 family protein -
  AA973_RS00110 (AA973_00105) cheV1 16135..17100 (+) 966 WP_064437113.1 chemotaxis protein CheV1 -
  AA973_RS00115 (AA973_00110) nspC 17097..18314 (+) 1218 WP_064437114.1 carboxynorspermidine decarboxylase -
  AA973_RS00120 (AA973_00115) lpxE 18324..18857 (-) 534 WP_230380712.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90155.55 Da        Isoelectric Point: 8.2577

>NTDB_id=146250 AA973_RS00095 WP_064437111.1 12006..14369(+) (comB4) [Helicobacter pylori strain ausabrJ05]
MLEKLLSAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDYQQNIQTDSKYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSLMHANRENFKDILS
YKAHSLQEILKSLEIQLKNYAPKLLSSNEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAIGALLYQETPLDIIFSIEPMSVNKTLSFLKERAKFSMSNLVKSELLEYQELVKTKRLSMQKFA
LNILIKAPSLENLDTQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKETARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTNFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAIFGAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDTITQNPKDLGLLAYYLFYKILEESRKDDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKNNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=146250 AA973_RS00095 WP_064437111.1 12006..14369(+) (comB4) [Helicobacter pylori strain ausabrJ05]
ATGTTAGAAAAGCTTTTAAGCGCTATCAAACAAAAAGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATCCTCC
GTTTAGAAGGGGTTAGTTACACCCATTTAAGCACAGAACAATTGCAAGATCTTTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGCCTTGTGGTTAAAAGGCGTAAAATTGATTACCAGCAAAACATTCAAACTGATTCTAA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAACAAAGAAGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCGCGC
ACTCTTTACAGGGCGTTTTAGAGCATAAGAAAAAATCCTTAATGCATGCCAATAGGGAAAATTTTAAGGACATTCTCTCT
TATAAGGCGCATTCTTTACAAGAAATTTTAAAAAGTTTAGAAATCCAGCTCAAAAATTATGCCCCCAAACTCTTAAGCTC
TAATGAGGTTTTGAATTTTTATGCGGAATACATTAACGGGTTTGATCTCCCTTTAAAGCCCCTAGTAGGGGGGTATTTGA
GCGATAGTTATATCGCTAGTTCCATCACCTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAGCGCATCACTTCTATAGCGATCGGGGCGCTTTTATACCAAGAGACGCC
TTTAGACATTATCTTTTCTATAGAGCCTATGAGCGTCAATAAAACGCTGAGTTTTTTAAAAGAGAGGGCCAAATTTAGCA
TGTCTAATCTCGTTAAAAGCGAGCTACTAGAATACCAAGAACTGGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
TTAAACATTCTTATCAAAGCCCCTAGTTTAGAGAATTTAGACACTCAAACAAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAATTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTAACTTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTAGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAACAACGCTAAAGAAACCGCCAGAGTGAACGGGCATACTTTAATCATAGGGGCTACTGGGAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCTTTTGACAGGATGCAAGGGCTG
TATTCTTTCACCAATTTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATCAACCCCTTTTGTTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTTGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTTTGGTGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGCTTTTAGTTTGTTGGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGATTGAGTTTAGAGCCGTATTTGAATAACCCTCTTTTTAACGC
TCTGAATGATGCGTTCAATTCTAACGCTTTTTTAAATGTGATAAACCTAGATACCATCACCCAAAACCCTAAAGATTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAGATGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTATTGAACACTAAAATTAACGCTTTAATCACGCAAGCCAGAAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGATATTTACCAATTAAGCGGGGTTAAAAACGCTCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTACCCGCAAAAAAACGCTAGGGAGTTGAAAAACAACTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAGTTCTAACATGATTGATGT
GAGTTTGGAAAGCTTAGGGCGTTATTTGAAAATCTTTAATTCAGACTCTAGCCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTAAAAAGCTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(425-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.459

100

0.975

Multiple sequence alignment