Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB2   Type   Machinery gene
Locus tag   AA973_RS00085 Genome accession   NZ_CP011485
Coordinates   11460..11741 (+) Length   93 a.a.
NCBI ID   WP_001272686.1    Uniprot ID   G2MDJ3
Organism   Helicobacter pylori strain ausabrJ05     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 6460..16741
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA973_RS00065 (AA973_00065) groES 7036..7392 (-) 357 WP_064437107.1 co-chaperone GroES -
  AA973_RS00070 (AA973_00070) dnaG 7668..9347 (+) 1680 WP_064437108.1 DNA primase -
  AA973_RS00075 (AA973_00075) - 9344..10396 (+) 1053 WP_064437109.1 MnmA/TRMU family protein -
  AA973_RS00080 (AA973_00080) - 10487..11314 (+) 828 WP_064437110.1 DUF5718 family protein -
  AA973_RS00085 (AA973_00085) comB2 11460..11741 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  AA973_RS00090 (AA973_00090) comB3 11741..12004 (+) 264 WP_000584956.1 hypothetical protein Machinery gene
  AA973_RS00095 (AA973_00095) comB4 12006..14369 (+) 2364 WP_064437111.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  AA973_RS00105 (AA973_00100) - 14696..16036 (+) 1341 WP_064437112.1 COG3014 family protein -

Sequence

Protein


Download         Length: 93 a.a.        Molecular weight: 10539.81 Da        Isoelectric Point: 9.1450

>NTDB_id=146248 AA973_RS00085 WP_001272686.1 11460..11741(+) (comB2) [Helicobacter pylori strain ausabrJ05]
MSAHFLKIIFLVGMCVSSLFAEGLEGFFNALEAQLKSPIAKGILMVIFIGIAIYVWRNLDRWKEILFTILGVVFGIFLFF
KAPSLANWFMGIF

Nucleotide


Download         Length: 282 bp        

>NTDB_id=146248 AA973_RS00085 WP_001272686.1 11460..11741(+) (comB2) [Helicobacter pylori strain ausabrJ05]
ATGTCCGCTCATTTTTTAAAAATCATTTTTTTAGTAGGCATGTGCGTTTCAAGTTTGTTCGCTGAAGGGTTAGAAGGGTT
TTTTAACGCCCTAGAAGCCCAACTCAAAAGCCCCATCGCTAAGGGGATTTTAATGGTGATTTTCATAGGGATCGCTATTT
ATGTGTGGAGGAATTTAGACAGGTGGAAAGAGATTTTATTCACGATCCTTGGCGTGGTGTTTGGGATTTTTTTATTCTTT
AAAGCCCCGAGTTTAGCGAATTGGTTTATGGGAATTTTTTAA

Domains

Predicted by InterproScan.

TrbC/VIRB2 pilin (TrbC)

(6-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G2MDJ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

98.925

100

0.989

Multiple sequence alignment