Detailed information NTG0144845

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AXE82_RS10800
• Genome accession: NZ_CP014234
• Coordinates: 2431422..2434019 (+)
• Length: 865 a.a.
• NCBI ID: WP_062334608.1
• Uniprot ID: A0A378QAE4
• Organism: Moraxella osloensis strain CCUG 350
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2426422..2439019

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AXE82_RS10785 (AXE82_10790)	-	2427291..2428706 (-)	1416	WP_062334602.1	alpha,alpha-trehalose-phosphate synthase (UDP-forming)	-
AXE82_RS10790 (AXE82_10795)	otsB	2428694..2429527 (-)	834	WP_062334605.1	trehalose-phosphatase	-
AXE82_RS10795 (AXE82_10800)	-	2429577..2430740 (-)	1164	WP_060994696.1	zinc-dependent alcohol dehydrogenase	-
AXE82_RS10800 (AXE82_10805)	clpC	2431422..2434019 (+)	2598	WP_062334608.1	ATP-dependent chaperone ClpB	Regulator

Sequence

Protein

• Length: 865 a.a.
• Molecular weight: 96041.37 Da
• Isoelectric Point: 5.2369

>NTDB_id=144845 AXE82_RS10800 WP_062334608.1 2431422..2434019(+) (clpC) [Moraxella osloensis strain CCUG 350]
MQFDKFTNALQNALQQAQTLAVTRDHTAIEPIHLLSVLLNEPSNANVYEQAGANLNQLKTEVQQALNNQAVIGTPTGDVN
LSPNTVKILNLAERHAQKAGDQFLSTDWVLVALAETGDTAKLLKKAGVNEPKLRQVINFIRGGDKVDTQNSEDQRDALNK
YTIDLTARAESGELDPVIGRDDVIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQKIVNGDVPEGLRNKRVLSLDLG
ALIAGAKFRGEFEERLKAVLKDLAKSKGQVILFIDEIHTLVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYI
EKDAALERRFQKVFVDEPTVEDTIAILRGLKERYELHHGVDIQDSAIIAAAQMSNRYITDRKLPDKAIDLLDEAASRLKM
ELDSKPEALGKLESRLIQLKMQRETLKHEDDEGAKSQLKLLDTQISELEKEYADLNEIWQAEKALVKGSQQLKDELDKAR
IAYEKAQREGDYETMSKLQYETIPQLEKRIKDSDLAEQKEQAGEAPSVKLLRNKVTENEIAEVVAAATGIPVTKMMQGER
EKMLHMEEKLHERVVGQDEAVRAVANAVRRSRAGLSDPNRPSGSFLFLGPTGVGKTELTKALASFLFDDENAMIRIDMSE
FMEKHSVSRLVGAPPGYVGYEEGGVLTEAVRRRPYSVVLFDEVEKAHPDVFNILLQVLDDGRLTDSQGRVVDFKNTVIIM
TSNLGSHKIQEMAGDSYEEIKAAVMNSVNQHFRPEFVNRIDEIVVFHPLGQEQMAGIADIQLSRLRKRLQERDMDIVLSD
EAMTKLVAVGYDPVYGARPLKRAIQQAIENPLSVKLLSGEFVAGDTIKVDVDGQGNFTFDKLRMS

Nucleotide

• Length: 2598 bp

>NTDB_id=144845 AXE82_RS10800 WP_062334608.1 2431422..2434019(+) (clpC) [Moraxella osloensis strain CCUG 350]
ATGCAATTTGATAAATTTACCAATGCCTTACAAAACGCGTTGCAGCAAGCACAAACGCTCGCTGTCACTCGTGACCATAC
TGCGATTGAGCCGATTCATTTATTGTCAGTGCTACTCAATGAACCGAGTAATGCCAATGTATATGAACAAGCAGGCGCAA
ACTTAAATCAGTTAAAAACAGAGGTGCAACAAGCGCTCAACAACCAAGCGGTGATTGGCACACCCACAGGTGATGTCAAT
CTGAGCCCAAATACGGTTAAGATTTTAAATCTAGCCGAGCGTCATGCGCAAAAAGCGGGCGATCAGTTCTTATCTACTGA
CTGGGTGCTGGTTGCCCTAGCCGAGACAGGCGATACCGCAAAACTGCTCAAAAAAGCAGGGGTCAATGAACCAAAACTAA
GACAAGTCATTAATTTTATTCGTGGGGGTGATAAAGTGGATACACAAAATAGCGAAGACCAACGTGATGCCTTAAATAAA
TATACCATCGATTTAACCGCACGTGCCGAATCGGGCGAACTTGACCCCGTGATTGGGCGTGATGATGTAATCCGCCGCAC
CATTCAAGTGTTGTCACGCCGTACCAAAAACAACCCGGTGCTCATTGGTGAGCCGGGGGTAGGTAAAACTGCCATTGTCG
AAGGATTGGCACAAAAAATCGTCAATGGTGACGTGCCAGAAGGCTTGCGCAACAAACGCGTATTATCGCTTGATTTGGGG
GCACTGATTGCGGGGGCAAAATTCCGTGGTGAGTTTGAAGAACGCCTAAAAGCGGTACTTAAAGACTTAGCAAAAAGCAA
AGGGCAAGTCATTTTATTTATTGATGAAATTCATACCTTGGTCGGTGCCGGTAAAGCCGATGGCGCGATGGATGCGGGTA
ATATGCTCAAACCTGCGTTAGCGCGTGGTGAGCTGCACTGTGTGGGCGCGACTACCCTGGATGAATACCGCCAATATATC
GAAAAAGATGCCGCCCTTGAGCGTCGTTTTCAAAAAGTATTTGTTGATGAGCCTACCGTGGAAGATACCATTGCCATTTT
GCGCGGTCTAAAAGAACGTTATGAACTGCATCACGGTGTTGATATCCAAGACAGTGCGATTATTGCCGCCGCGCAGATGA
GTAACCGTTACATCACCGACCGCAAATTGCCCGACAAAGCCATTGATTTGTTGGATGAAGCCGCTAGCCGTCTAAAAATG
GAACTTGATAGTAAACCAGAAGCCTTGGGCAAATTAGAAAGCCGTTTGATTCAGCTCAAAATGCAACGTGAAACGTTAAA
GCATGAAGATGACGAAGGCGCAAAATCACAGCTAAAACTGCTCGACACCCAAATCAGCGAGCTTGAAAAAGAATACGCAG
ATTTAAACGAAATTTGGCAAGCAGAAAAAGCCCTCGTTAAAGGTAGCCAACAGCTCAAAGACGAGCTTGATAAAGCACGT
ATCGCCTATGAAAAAGCCCAGCGTGAAGGTGACTACGAGACCATGTCAAAACTGCAATACGAGACCATTCCCCAACTGGA
AAAACGTATTAAAGACTCTGACTTGGCTGAGCAAAAAGAGCAAGCAGGTGAAGCGCCAAGCGTCAAACTGCTACGTAACA
AAGTCACCGAAAACGAAATCGCTGAAGTCGTTGCCGCCGCAACGGGCATCCCTGTTACCAAAATGATGCAAGGCGAACGT
GAAAAAATGCTGCACATGGAAGAAAAACTGCATGAGCGCGTAGTCGGTCAAGATGAAGCGGTACGAGCAGTCGCCAATGC
GGTGCGCCGTAGTCGTGCCGGGCTGTCTGACCCCAATCGTCCTAGCGGTTCGTTCTTGTTCCTAGGTCCGACAGGCGTAG
GTAAAACTGAATTGACCAAAGCGTTGGCAAGTTTCTTGTTTGATGATGAAAATGCCATGATTCGTATTGATATGTCTGAA
TTTATGGAAAAACACAGTGTCAGCCGTCTTGTCGGTGCACCCCCAGGCTACGTGGGTTATGAAGAAGGTGGGGTATTGAC
CGAAGCCGTACGCCGCCGACCCTATAGCGTGGTATTGTTTGATGAAGTAGAAAAAGCGCATCCCGATGTGTTTAATATCC
TACTGCAAGTGCTAGACGATGGTCGCTTGACCGACAGCCAAGGCCGCGTTGTGGACTTTAAAAACACCGTCATTATCATG
ACCTCAAACCTTGGTTCGCATAAAATCCAAGAGATGGCAGGCGATAGCTACGAAGAAATCAAAGCGGCAGTGATGAATTC
AGTCAATCAGCATTTCCGCCCAGAGTTTGTCAACCGTATTGATGAAATCGTGGTGTTCCATCCATTAGGGCAAGAGCAAA
TGGCGGGTATTGCAGATATTCAACTGTCACGCTTACGCAAACGTCTCCAAGAGCGTGACATGGATATTGTATTGTCAGAT
GAAGCCATGACGAAATTGGTCGCTGTGGGTTATGACCCTGTGTATGGTGCAAGACCGCTAAAACGTGCCATCCAGCAAGC
AATCGAGAATCCGTTATCAGTCAAATTGCTATCGGGCGAGTTTGTAGCGGGTGACACCATCAAAGTGGATGTCGATGGAC
AGGGCAATTTTACGTTTGATAAATTACGTATGAGTTAA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (200-333)

• AAA lid domain (AAA_lid_9) (339-439)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-763)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (769-849)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (92-140)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-66)

3D structure

• AlphaFold DB: A0A378QAE4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	46.804	100	0.474
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.873	100	0.438
clpE	Streptococcus pneumoniae TIGR4	48.392	79.075	0.383
clpC	Lactococcus lactis subsp. cremoris KW2	47.941	78.613	0.377
clpE	Streptococcus mutans UA159	46.744	79.884	0.373