Detailed information NTG0144801

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AXE82_RS02680
• Genome accession: NZ_CP014234
• Coordinates: 624656..627115 (-)
• Length: 819 a.a.
• NCBI ID: WP_062331124.1
• Uniprot ID: A0A378Q927
• Organism: Moraxella osloensis strain CCUG 350
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 619656..632115

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AXE82_RS02660 (AXE82_02660)	-	620249..621952 (+)	1704	WP_406946760.1	sigma 54-interacting transcriptional regulator	-
AXE82_RS02665 (AXE82_02665)	-	621949..622947 (+)	999	WP_062331118.1	serine/threonine-protein kinase	-
AXE82_RS02675 (AXE82_02675)	-	623397..624548 (+)	1152	WP_062331121.1	AAA family ATPase	-
AXE82_RS02680 (AXE82_02680)	clpC	624656..627115 (-)	2460	WP_062331124.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
AXE82_RS02685 (AXE82_02685)	-	627509..627994 (-)	486	WP_227523040.1	ATP-dependent Clp protease adaptor ClpS	-
AXE82_RS02690 (AXE82_02690)	-	628037..628897 (-)	861	WP_062331127.1	hypothetical protein	-
AXE82_RS02695 (AXE82_02695)	argC	629200..630267 (-)	1068	WP_062331130.1	N-acetyl-gamma-glutamyl-phosphate reductase	-
AXE82_RS02700 (AXE82_02700)	hemE	630289..631398 (-)	1110	WP_062331135.1	uroporphyrinogen decarboxylase	-

Sequence

Protein

• Length: 819 a.a.
• Molecular weight: 90786.20 Da
• Isoelectric Point: 4.8484

>NTDB_id=144801 AXE82_RS02680 WP_062331124.1 624656..627115(-) (clpC) [Moraxella osloensis strain CCUG 350]
MLSLELQSTLRLVVTLAKQRAHEYLTVEHLLLALLENENAVEALVACAVNVDQLGKDLTQYIDEHTPTVDINEDYSPQPT
RSFDRILQRAIFHVQSVASSRLVEGSDLLVSMFSEHDTYAVYLLKKQGVTRLELTQYLSHGQDKKVRDKLTSVETEETGE
KSSKDPLTEFTINLNQKASTGGTDPLIGRQAEIERTAQILCRRRKNNPLLVGDPGVGKTSIAEGLAWLIVNDKAPKPLSG
CVVYSLDIGALIAGTKYRGDFEKRMKALLDALKAKPNAILFIDEIHMIIGAGSSMSSNMDVSNLIKPALASGELRCIGST
TFTEYRQVFEKDHALSRRFQKIDVNEPSIDETIDILRGLKKQYEKFHNVSYTDQALQSAVNLAVKHIHERFLPDKAIDVI
DEAGAFVRLQKQAENHVESGVDSNQSTDTVANDKLSNQPVVDEDALVDDLDVSHAADGVVEPEAMLSEADNKIIDAAQQD
GEVVIDVPQIEYIISKIARIPPKSVSTDDKSVLQNLESNLKHLVFGQDEAIKNLADAIKLSRAGLKPDDKPIGSFMFAGP
TGVGKTEVSRQLANLLGIELVRFDMSEYMEAHTASRLIGAPPGYVGFDQGGLLTEKINQFPHCVLLLDEIEKAHPDVFNL
LLQVMDHGALTDNNGRTSSFKQVILIMTTNVGADSISRNSMGFTKQDHSRDNSEAMKRMFTPEFRNRLDAIIQFNPLDQN
VIVSVVDKFLVELQAQLDDKKVVLEIDDEVRNYLAEKGYDRLMGARPMNRLIQDEIKKPLAEQILFGDLVNGGTVSIRMN
ADKTAIELVPIDEKQIDNV

Nucleotide

• Length: 2460 bp

>NTDB_id=144801 AXE82_RS02680 WP_062331124.1 624656..627115(-) (clpC) [Moraxella osloensis strain CCUG 350]
ATGTTAAGTTTAGAATTACAAAGCACGTTGCGGTTGGTAGTGACACTCGCAAAACAACGTGCACACGAATATTTAACGGT
CGAGCATCTGCTATTGGCACTGCTAGAGAATGAAAATGCGGTAGAAGCCTTGGTGGCTTGTGCAGTCAATGTGGATCAGC
TTGGCAAAGATTTGACCCAGTATATTGATGAACATACCCCAACGGTCGATATCAACGAAGATTACTCGCCACAACCAACG
CGCAGTTTTGACCGTATTTTGCAGCGGGCGATTTTTCATGTGCAATCGGTTGCTAGCAGCCGTTTGGTAGAAGGCTCAGA
TTTGCTAGTGTCGATGTTCTCAGAGCATGACACTTACGCGGTGTACCTGCTTAAAAAACAAGGGGTGACGCGACTTGAAT
TAACCCAGTACCTATCGCATGGTCAAGACAAAAAGGTACGCGATAAATTGACCAGTGTAGAGACTGAAGAAACGGGTGAA
AAATCCAGCAAAGACCCATTGACTGAATTTACCATTAATCTCAATCAAAAAGCCTCTACCGGCGGCACCGATCCGTTAAT
TGGTCGCCAAGCAGAAATCGAGCGTACCGCGCAGATTTTATGCCGTCGCCGCAAAAACAATCCATTACTGGTGGGTGACC
CAGGGGTGGGTAAAACGTCGATTGCGGAAGGCTTGGCATGGCTGATTGTTAATGACAAAGCACCAAAACCATTATCAGGT
TGTGTGGTTTATAGTTTAGATATTGGTGCATTGATTGCCGGTACAAAATACCGCGGCGATTTTGAAAAACGTATGAAAGC
GCTATTAGATGCCTTAAAAGCCAAGCCCAATGCGATTTTATTTATTGATGAAATCCATATGATTATTGGCGCAGGCTCAT
CGATGAGCAGCAATATGGATGTGTCAAATTTAATTAAACCTGCGTTGGCATCAGGTGAGCTGCGTTGTATCGGCTCAACT
ACCTTTACCGAATACCGCCAAGTGTTTGAAAAAGACCATGCCTTAAGTCGCCGTTTCCAAAAAATTGATGTCAACGAGCC
ATCGATTGATGAAACGATTGATATTCTACGCGGTCTGAAAAAACAATATGAGAAATTCCATAACGTAAGCTATACCGACC
AGGCACTACAAAGTGCCGTGAATCTAGCGGTAAAACACATTCACGAACGTTTTTTGCCTGACAAAGCCATTGATGTGATT
GATGAAGCGGGTGCATTTGTTCGCCTGCAAAAACAAGCCGAAAATCATGTTGAATCTGGTGTGGACAGCAATCAATCCAC
TGATACTGTAGCAAATGACAAGCTATCAAATCAGCCTGTGGTGGATGAAGACGCGCTTGTCGATGACTTAGATGTTAGCC
ATGCAGCAGATGGTGTTGTCGAACCTGAAGCTATGTTAAGCGAAGCCGATAATAAAATAATTGACGCGGCACAACAAGAT
GGCGAGGTAGTGATTGATGTCCCGCAAATTGAATACATTATCTCAAAAATTGCGCGCATCCCGCCAAAATCAGTCTCAAC
GGATGACAAATCGGTGCTACAAAATCTTGAAAGCAACCTAAAACATCTGGTGTTTGGTCAAGATGAAGCCATCAAAAACT
TGGCAGATGCCATCAAGTTGTCACGTGCAGGCTTAAAACCAGATGATAAACCGATTGGTTCGTTTATGTTTGCCGGTCCT
ACGGGTGTCGGTAAAACTGAAGTCAGTCGTCAGTTAGCGAATTTGTTAGGCATTGAGCTGGTTCGTTTTGATATGTCTGA
GTATATGGAAGCACATACGGCGTCACGCCTGATTGGGGCACCGCCAGGCTATGTGGGCTTTGATCAGGGTGGTTTATTAA
CCGAAAAAATCAATCAATTCCCGCATTGTGTGCTATTGCTAGATGAGATTGAAAAAGCCCATCCTGATGTATTTAACTTG
CTGCTCCAAGTGATGGATCATGGCGCGCTCACCGACAATAACGGCCGTACATCAAGCTTTAAGCAAGTGATACTAATCAT
GACCACCAACGTCGGCGCTGATAGCATCAGTCGCAACAGCATGGGCTTTACCAAACAAGACCATAGCCGCGACAATAGTG
AGGCGATGAAACGGATGTTTACCCCAGAGTTTCGCAATCGTTTAGATGCCATCATTCAATTTAACCCATTGGATCAAAAT
GTCATTGTATCTGTGGTTGATAAATTCTTGGTTGAGCTGCAAGCCCAGCTCGATGACAAGAAAGTGGTGCTTGAAATTGA
TGATGAAGTCAGAAATTATCTGGCAGAAAAAGGTTACGATCGTCTCATGGGTGCGCGCCCAATGAACCGCTTGATTCAAG
ATGAAATCAAAAAACCATTGGCAGAGCAAATATTATTTGGTGATTTGGTCAATGGCGGTACGGTTTCGATTCGTATGAAT
GCAGATAAAACAGCGATTGAGCTTGTGCCCATTGATGAAAAGCAAATTGACAATGTCTAG

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-62)

• ATPase family associated with various cellular activities (AAA) (AAA) (209-308)

• AAA lid domain (AAA_lid_9) (348-431)

• AAA domain (Cdc48 subfamily) (AAA_2) (550-711)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (717-796)

3D structure

• AlphaFold DB: A0A378Q927

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	40.42	98.779	0.399
clpC	Streptococcus mutans UA159	36.643	100	0.379
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	37.167	100	0.375
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	38.065	97.192	0.37