Detailed information NTG0143258

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: AVT04_RS07755
• Genome accession: NZ_CP013939
• Coordinates: 1449037..1450122 (+)
• Length: 361 a.a.
• NCBI ID: WP_011226304.1
• Uniprot ID: Q5M3H6
• Organism: Streptococcus thermophilus strain S9
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1444037..1455122

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AVT04_RS07740 (AVT04_07740)	amiA	1444579..1446546 (+)	1968	WP_059257397.1	peptide ABC transporter substrate-binding protein	Regulator
AVT04_RS07745 (AVT04_07745)	amiC	1446608..1448101 (+)	1494	WP_011227407.1	ABC transporter permease	Regulator
AVT04_RS07750 (AVT04_07750)	amiD	1448101..1449027 (+)	927	WP_002946409.1	oligopeptide ABC transporter permease OppC	Regulator
AVT04_RS07755 (AVT04_07755)	amiE	1449037..1450122 (+)	1086	WP_011226304.1	ABC transporter ATP-binding protein	Regulator
AVT04_RS07760 (AVT04_07760)	-	1450115..1451044 (+)	930	WP_002951426.1	ATP-binding cassette domain-containing protein	-
AVT04_RS07765 (AVT04_07765)	-	1451094..1451879 (-)	786	WP_002951425.1	hypothetical protein	-
AVT04_RS07770 (AVT04_07770)	-	1451891..1452589 (-)	699	WP_011226301.1	ABC transporter ATP-binding protein	-
AVT04_RS07775 (AVT04_07775)	-	1452594..1452971 (-)	378	WP_011226300.1	GntR family transcriptional regulator	-
AVT04_RS07780 (AVT04_07780)	-	1453154..1453948 (+)	795	WP_059257398.1	HAD hydrolase family protein	-
AVT04_RS07785 (AVT04_07785)	-	1453941..1454756 (+)	816	WP_011227405.1	Cof-type HAD-IIB family hydrolase	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39864.62 Da
• Isoelectric Point: 4.7435

>NTDB_id=143258 AVT04_RS07755 WP_011226304.1 1449037..1450122(+) (amiE) [Streptococcus thermophilus strain S9]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=143258 AVT04_RS07755 WP_011226304.1 1449037..1450122(+) (amiE) [Streptococcus thermophilus strain S9]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-300)

3D structure

• AlphaFold DB: Q5M3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus thermophilus LMG 18311	100	100	1
amiE	Streptococcus thermophilus LMD-9	100	100	1
amiE	Streptococcus salivarius strain HSISS4	96.953	100	0.97
oppD	Streptococcus mutans UA159	54.441	96.676	0.526