Detailed information
Bioinformatically predicted
Overview
| Name | amiC | Type | Regulator |
| Locus tag | MNA02_RS06845 | Genome accession | NZ_CP010999 |
| Coordinates | 1309763..1311256 (-) | Length | 497 a.a. |
| NCBI ID | WP_011681416.1 | Uniprot ID | - |
| Organism | Streptococcus thermophilus strain MN-BM-A02 | ||
| Function | internalize XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1291289..1362322 | 1309763..1311256 | within | 0 |
Gene organization within MGE regions
Location: 1291289..1362322
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MNA02_RS06760 (MNA02_1385) | liaF | 1291297..1291995 (-) | 699 | WP_011226289.1 | cell wall-active antibiotics response protein LiaF | - |
| MNA02_RS11745 (MNA02_1386) | - | 1292250..1292417 (-) | 168 | WP_014608530.1 | potassium channel family protein | - |
| MNA02_RS06765 (MNA02_1387) | stkP/pknB | 1293055..1294926 (-) | 1872 | WP_024703938.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| MNA02_RS06770 (MNA02_1388) | - | 1294926..1295663 (-) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| MNA02_RS06775 (MNA02_1389) | rsmB | 1295707..1297029 (-) | 1323 | WP_014608533.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| MNA02_RS06780 (MNA02_1390) | fmt | 1297019..1297954 (-) | 936 | WP_014608534.1 | methionyl-tRNA formyltransferase | - |
| MNA02_RS06785 (MNA02_1391) | - | 1297972..1300368 (-) | 2397 | WP_024703939.1 | primosomal protein N' | - |
| MNA02_RS06790 (MNA02_1392) | rpoZ | 1300510..1300824 (-) | 315 | WP_002951415.1 | DNA-directed RNA polymerase subunit omega | - |
| MNA02_RS06795 (MNA02_1393) | gmk | 1300846..1301475 (-) | 630 | WP_014608537.1 | guanylate kinase | - |
| MNA02_RS06800 (MNA02_1394) | ftsY | 1301701..1303092 (-) | 1392 | WP_014608538.1 | signal recognition particle-docking protein FtsY | - |
| MNA02_RS06805 (MNA02_1395) | - | 1303106..1303921 (-) | 816 | WP_011226298.1 | Cof-type HAD-IIB family hydrolase | - |
| MNA02_RS06810 (MNA02_1396) | - | 1303914..1304708 (-) | 795 | WP_011681412.1 | HAD-IIB family hydrolase | - |
| MNA02_RS06815 (MNA02_1397) | - | 1304893..1305270 (+) | 378 | WP_011681413.1 | GntR family transcriptional regulator | - |
| MNA02_RS06820 (MNA02_1398) | - | 1305275..1305973 (+) | 699 | WP_023909821.1 | ABC transporter ATP-binding protein | - |
| MNA02_RS06825 (MNA02_1399) | - | 1305985..1306770 (+) | 786 | WP_002951425.1 | hypothetical protein | - |
| MNA02_RS06830 (MNA02_1400) | amiF | 1306820..1307749 (-) | 930 | WP_002951426.1 | ATP-binding cassette domain-containing protein | Regulator |
| MNA02_RS06835 (MNA02_1401) | amiE | 1307742..1308827 (-) | 1086 | WP_011226304.1 | ABC transporter ATP-binding protein | Regulator |
| MNA02_RS06840 (MNA02_1402) | amiD | 1308837..1309763 (-) | 927 | WP_002946409.1 | oligopeptide ABC transporter permease OppC | Regulator |
| MNA02_RS06845 (MNA02_1403) | amiC | 1309763..1311256 (-) | 1494 | WP_011681416.1 | ABC transporter permease | Regulator |
| MNA02_RS06850 (MNA02_1404) | amiA | 1311318..1313285 (-) | 1968 | WP_024703940.1 | peptide ABC transporter substrate-binding protein | Regulator |
| MNA02_RS06855 (MNA02_1405) | - | 1313641..1314818 (+) | 1178 | Protein_1294 | ISL3 family transposase | - |
| MNA02_RS06860 (MNA02_1406) | amiA3 | 1314863..1316836 (-) | 1974 | WP_011681419.1 | peptide ABC transporter substrate-binding protein | Regulator |
| MNA02_RS06870 (MNA02_1408) | - | 1317141..1318288 (+) | 1148 | WP_095559415.1 | IS3 family transposase | - |
| MNA02_RS10440 | - | 1318326..1318510 (-) | 185 | Protein_1297 | IS3 family transposase | - |
| MNA02_RS11750 | - | 1318504..1318914 (-) | 411 | Protein_1298 | ATP-binding cassette domain-containing protein | - |
| MNA02_RS06885 (MNA02_1411) | - | 1318946..1319260 (-) | 315 | Protein_1299 | TatD family hydrolase | - |
| MNA02_RS06890 (MNA02_1412) | - | 1319606..1320811 (+) | 1206 | WP_011681420.1 | OFA family MFS transporter | - |
| MNA02_RS10445 | - | 1320857..1322170 (-) | 1314 | Protein_1301 | IS3 family transposase | - |
| MNA02_RS06905 (MNA02_1417) | pta | 1322295..1323278 (-) | 984 | WP_011227420.1 | phosphate acetyltransferase | - |
| MNA02_RS06910 (MNA02_1418) | - | 1323292..1324188 (-) | 897 | WP_024703943.1 | RluA family pseudouridine synthase | - |
| MNA02_RS06915 (MNA02_1419) | - | 1324185..1325021 (-) | 837 | WP_014608552.1 | NAD kinase | - |
| MNA02_RS06920 (MNA02_1420) | - | 1324993..1325667 (-) | 675 | WP_011681427.1 | GTP pyrophosphokinase family protein | - |
| MNA02_RS06925 | - | 1325763..1326338 (+) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| MNA02_RS06930 (MNA02_1422) | - | 1326701..1327672 (+) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| MNA02_RS06935 (MNA02_1423) | - | 1327676..1328788 (+) | 1113 | WP_014608554.1 | cysteine desulfurase family protein | - |
| MNA02_RS06940 (MNA02_1424) | - | 1328790..1329137 (+) | 348 | WP_014608555.1 | DUF1831 domain-containing protein | - |
| MNA02_RS06945 (MNA02_1425) | - | 1329281..1329940 (+) | 660 | WP_024703944.1 | redox-sensing transcriptional repressor Rex | - |
| MNA02_RS06950 (MNA02_1426) | - | 1329933..1330628 (+) | 696 | WP_024703945.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| MNA02_RS06955 (MNA02_1427) | radC | 1330681..1331367 (-) | 687 | WP_014727630.1 | RadC family protein | - |
| MNA02_RS06960 (MNA02_1428) | - | 1331416..1333200 (-) | 1785 | WP_024703946.1 | rhamnan synthesis F family protein | - |
| MNA02_RS06965 (MNA02_1429) | - | 1333197..1334264 (-) | 1068 | WP_024703947.1 | glycosyltransferase family 2 protein | - |
| MNA02_RS06970 (MNA02_1430) | - | 1334284..1335489 (-) | 1206 | WP_014727633.1 | ABC transporter ATP-binding protein | - |
| MNA02_RS06975 (MNA02_1431) | - | 1335489..1336298 (-) | 810 | WP_024703948.1 | ABC transporter permease | - |
| MNA02_RS06980 (MNA02_1432) | - | 1336282..1337238 (-) | 957 | WP_024703949.1 | glycosyltransferase family 2 protein | - |
| MNA02_RS06985 (MNA02_1433) | cps2T | 1337235..1338383 (-) | 1149 | WP_024703950.1 | beta 1-4 rhamnosyltransferase Cps2T | - |
| MNA02_RS06990 (MNA02_1434) | - | 1338490..1340031 (-) | 1542 | WP_024703951.1 | DUF2142 domain-containing protein | - |
| MNA02_RS06995 (MNA02_1435) | - | 1340038..1341048 (-) | 1011 | WP_024703952.1 | glycosyltransferase | - |
| MNA02_RS07000 (MNA02_1436) | - | 1341048..1342322 (-) | 1275 | WP_024703953.1 | lipopolysaccharide biosynthesis protein | - |
| MNA02_RS07005 (MNA02_1437) | - | 1342315..1342647 (-) | 333 | WP_011226332.1 | DUF2304 domain-containing protein | - |
| MNA02_RS07010 (MNA02_1438) | - | 1342653..1343348 (-) | 696 | WP_024703954.1 | glycosyltransferase family 2 protein | - |
| MNA02_RS07015 (MNA02_1439) | rfbD | 1343425..1344276 (-) | 852 | WP_014621820.1 | dTDP-4-dehydrorhamnose reductase | - |
| MNA02_RS07020 (MNA02_1440) | - | 1344353..1345687 (-) | 1335 | WP_024703955.1 | DUF6056 family protein | - |
| MNA02_RS07025 (MNA02_1441) | - | 1345800..1346726 (-) | 927 | WP_024703956.1 | glycosyltransferase family 2 protein | - |
| MNA02_RS07030 (MNA02_1442) | - | 1346736..1347071 (-) | 336 | WP_024703957.1 | metal-sulfur cluster assembly factor | - |
| MNA02_RS10850 (MNA02_1443) | rpoD | 1347125..1348234 (-) | 1110 | WP_011227440.1 | RNA polymerase sigma factor RpoD | - |
| MNA02_RS10855 (MNA02_1444) | dnaG | 1348238..1350049 (-) | 1812 | WP_024703958.1 | DNA primase | - |
| MNA02_RS07045 (MNA02_1445) | mscL | 1350192..1350272 (+) | 81 | Protein_1330 | large conductance mechanosensitive channel protein MscL | - |
| MNA02_RS07050 (MNA02_1446) | rpsU | 1350432..1350608 (-) | 177 | WP_011681449.1 | 30S ribosomal protein S21 | - |
| MNA02_RS07055 (MNA02_1447) | - | 1350802..1351596 (-) | 795 | WP_023909836.1 | ABC transporter substrate-binding protein | - |
| MNA02_RS07060 (MNA02_1448) | - | 1351658..1352767 (-) | 1110 | WP_024703959.1 | aminotransferase | - |
| MNA02_RS07065 (MNA02_1449) | - | 1353115..1353912 (-) | 798 | WP_014621828.1 | transporter substrate-binding domain-containing protein | - |
| MNA02_RS07070 (MNA02_1450) | - | 1353909..1354739 (-) | 831 | WP_014621829.1 | transporter substrate-binding domain-containing protein | - |
| MNA02_RS07075 (MNA02_1451) | - | 1354953..1355417 (-) | 465 | WP_011681454.1 | 8-oxo-dGTP diphosphatase | - |
| MNA02_RS07080 (MNA02_1452) | uvrB | 1355462..1357453 (-) | 1992 | WP_014608579.1 | excinuclease ABC subunit UvrB | - |
| MNA02_RS07085 (MNA02_1453) | - | 1357600..1358067 (-) | 468 | WP_014608580.1 | hypothetical protein | - |
| MNA02_RS10455 | - | 1358140..1359076 (-) | 937 | Protein_1339 | CPBP family intramembrane glutamic endopeptidase | - |
| MNA02_RS07100 (MNA02_1457) | - | 1359275..1361485 (+) | 2211 | WP_014727645.1 | ABC transporter substrate-binding protein/permease | - |
| MNA02_RS07105 (MNA02_1458) | - | 1361485..1362225 (+) | 741 | WP_024703961.1 | amino acid ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 497 a.a. Molecular weight: 55635.50 Da Isoelectric Point: 10.0972
>NTDB_id=141233 MNA02_RS06845 WP_011681416.1 1309763..1311256(-) (amiC) [Streptococcus thermophilus strain MN-BM-A02]
MKKYILLRTLRSLLSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKANYENTIYERLGYIDYYDTKELQEKAS
SLDKSVTTKPTKENKAVYQKYVDSLGRGWRLHQFKQSKQFYATRDVPVLERVFGFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNGQFPFVHQNFVKMNLGTSYPTYAGQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTLFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK
MKKYILLRTLRSLLSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKANYENTIYERLGYIDYYDTKELQEKAS
SLDKSVTTKPTKENKAVYQKYVDSLGRGWRLHQFKQSKQFYATRDVPVLERVFGFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNGQFPFVHQNFVKMNLGTSYPTYAGQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTLFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK
Nucleotide
Download Length: 1494 bp
>NTDB_id=141233 MNA02_RS06845 WP_011681416.1 1309763..1311256(-) (amiC) [Streptococcus thermophilus strain MN-BM-A02]
ATGAAAAAATACATTTTATTGAGAACACTCCGTTCTCTATTGTCAATATTTGTCGTGACGGCTTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAAGACCCGAACTACAACAAGATTGCTAAGACAGCTGATTCTAAGG
CTAACTATGAAAATACAATCTATGAACGCTTGGGTTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAAAGCTAGC
TCCCTTGATAAGTCAGTAACCACTAAGCCAACAAAAGAAAATAAGGCTGTCTACCAAAAATATGTGGATAGTTTAGGACG
TGGTTGGCGTTTGCATCAGTTCAAGCAAAGTAAACAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
GCTTCTATACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTATATC
CGTATTGAAAATGACCCAGCTATCGGTTGGTCAGTTGTTGGTTCAGGGACTAAGCATAAATATTTGCTTTACTTTAATGG
TCAGTTCCCATTTGTTCACCAAAATTTTGTGAAGATGAATCTTGGAACTTCATACCCAACTTATGCTGGGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTACTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACACTCTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTCGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGATTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA
ATGAAAAAATACATTTTATTGAGAACACTCCGTTCTCTATTGTCAATATTTGTCGTGACGGCTTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAAGACCCGAACTACAACAAGATTGCTAAGACAGCTGATTCTAAGG
CTAACTATGAAAATACAATCTATGAACGCTTGGGTTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAAAGCTAGC
TCCCTTGATAAGTCAGTAACCACTAAGCCAACAAAAGAAAATAAGGCTGTCTACCAAAAATATGTGGATAGTTTAGGACG
TGGTTGGCGTTTGCATCAGTTCAAGCAAAGTAAACAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
GCTTCTATACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTATATC
CGTATTGAAAATGACCCAGCTATCGGTTGGTCAGTTGTTGGTTCAGGGACTAAGCATAAATATTTGCTTTACTTTAATGG
TCAGTTCCCATTTGTTCACCAAAATTTTGTGAAGATGAATCTTGGAACTTCATACCCAACTTATGCTGGGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTACTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACACTCTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTCGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGATTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiC | Streptococcus thermophilus LMD-9 |
100 |
100 |
1 |
| amiC | Streptococcus thermophilus LMG 18311 |
99.195 |
100 |
0.992 |
| amiC | Streptococcus salivarius strain HSISS4 |
96.982 |
100 |
0.97 |