Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   FORC12_RS12925 Genome accession   NZ_CP010998
Coordinates   2545466..2546035 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain FORC_012 isolate human sputum     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2540466..2551035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FORC12_RS12900 (FORC12_2329) cysE 2541679..2542326 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  FORC12_RS12905 (FORC12_2330) cysS 2542310..2543710 (+) 1401 WP_000631974.1 cysteine--tRNA ligase -
  FORC12_RS12910 (FORC12_2331) - 2543703..2544107 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  FORC12_RS12915 (FORC12_2332) rlmB 2544115..2544861 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  FORC12_RS12920 (FORC12_2333) - 2544861..2545385 (+) 525 WP_000664738.1 NYN domain-containing protein -
  FORC12_RS12925 (FORC12_2334) sigH 2545466..2546035 (+) 570 WP_000872873.1 RNA polymerase sigma factor Regulator
  FORC12_RS14795 rpmG 2546150..2546293 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  FORC12_RS12930 (FORC12_2335) secE 2546349..2546531 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  FORC12_RS12935 (FORC12_2336) nusG 2546544..2547092 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  FORC12_RS12940 (FORC12_2337) rplK 2547273..2547695 (+) 423 WP_001085791.1 50S ribosomal protein L11 -
  FORC12_RS12945 (FORC12_2338) rplA 2547903..2548595 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  FORC12_RS12950 (FORC12_2339) rplJ 2548867..2549367 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  FORC12_RS12955 (FORC12_2340) rplL 2549410..2549778 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  FORC12_RS12960 (FORC12_2341) - 2549953..2550561 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=141194 FORC12_RS12925 WP_000872873.1 2545466..2546035(+) (sigH) [Staphylococcus aureus strain FORC_012 isolate human sputum]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=141194 FORC12_RS12925 WP_000872873.1 2545466..2546035(+) (sigH) [Staphylococcus aureus strain FORC_012 isolate human sputum]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment