Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   FORC12_RS02330 Genome accession   NZ_CP010998
Coordinates   441327..442199 (+) Length   290 a.a.
NCBI ID   WP_000593192.1    Uniprot ID   A0A140HKN1
Organism   Staphylococcus aureus strain FORC_012 isolate human sputum     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 436327..447199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FORC12_RS02310 (FORC12_0438) sucC 436441..437607 (+) 1167 WP_001020801.1 ADP-forming succinate--CoA ligase subunit beta -
  FORC12_RS02315 (FORC12_0439) sucD 437629..438537 (+) 909 WP_000110251.1 succinate--CoA ligase subunit alpha -
  FORC12_RS02320 (FORC12_0440) - 438764..439882 (+) 1119 WP_001041669.1 LysM peptidoglycan-binding domain-containing protein -
  FORC12_RS02325 (FORC12_0441) fmhC 439910..441154 (+) 1245 WP_000672869.1 FemA/FemB family glycyltransferase FmhC -
  FORC12_RS02330 (FORC12_0442) dprA 441327..442199 (+) 873 WP_000593192.1 DNA-processing protein DprA Machinery gene
  FORC12_RS02335 (FORC12_0443) topA 442373..444448 (+) 2076 WP_001557331.1 type I DNA topoisomerase -
  FORC12_RS02340 (FORC12_0444) trmFO 444604..445911 (+) 1308 WP_000195258.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33564.99 Da        Isoelectric Point: 9.5094

>NTDB_id=141157 FORC12_RS02330 WP_000593192.1 441327..442199(+) (dprA) [Staphylococcus aureus strain FORC_012 isolate human sputum]
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=141157 FORC12_RS02330 WP_000593192.1 441327..442199(+) (dprA) [Staphylococcus aureus strain FORC_012 isolate human sputum]
TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATTGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A140HKN1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

100

100

1
  dprA Staphylococcus aureus N315

99.655

100

0.997

Multiple sequence alignment