Detailed information NTG0140676

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: TO66_RS27000
• Genome accession: NZ_CP010892
• Coordinates: 5938070..5939392 (+)
• Length: 440 a.a.
• NCBI ID: WP_044465138.1
• Uniprot ID: A0A0C5EBK8
• Organism: Pseudomonas sp. MRSN 12121 strain MRSN12121
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5933070..5944392

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TO66_RS26980 (TO66_26970)	pgeF	5934562..5935287 (-)	726	WP_044465135.1	peptidoglycan editing factor PgeF	-
TO66_RS26985 (TO66_26975)	rluD	5935284..5936246 (-)	963	WP_009050933.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
TO66_RS26990 (TO66_26980)	-	5936398..5937420 (+)	1023	WP_044465136.1	outer membrane protein assembly factor BamD	-
TO66_RS26995 (TO66_26985)	-	5937553..5937786 (+)	234	WP_044465137.1	PP0621 family protein	-
TO66_RS27000 (TO66_26990)	pilR	5938070..5939392 (+)	1323	WP_044465138.1	sigma-54 dependent transcriptional regulator	Regulator
TO66_RS27005 (TO66_26995)	thiO	5939389..5940489 (-)	1101	WP_044465139.1	glycine oxidase ThiO	-
TO66_RS27010 (TO66_27000)	-	5940541..5940942 (-)	402	WP_044465140.1	type IV pilin protein	-
TO66_RS27015 (TO66_27005)	-	5940956..5944033 (-)	3078	WP_044465141.1	pilus assembly protein	-

Sequence

Protein

• Length: 440 a.a.
• Molecular weight: 48468.79 Da
• Isoelectric Point: 8.6067

>NTDB_id=140676 TO66_RS27000 WP_044465138.1 5938070..5939392(+) (pilR) [Pseudomonas sp. MRSN 12121 strain MRSN12121]
MGPRQKVLIVDDDPGTREYLEISLGRMRRHTRSVCTLGEARRCLEREGFDLCLSDLHLPDGTGLELLEHIRHQQLPTSLA
ILSACALQETAAQALQAGAIDVLSKPVPLARLHKLLNDIRPEAISFASRTLLGDSAPMQALRGQIGKLAGSRAAIYISGE
SGSGKELVARALHDQGARASRAFVAVNCGAIPAELMESEFFGHRKGSFSGAVEDHPGLFQAAHGGTLFLDEVADLPLAMQ
VKLLRALQQKAVRRVGGHQEVQVDVRILCATHKPLLAEVQAGRFRQDLYYRLNVIELPVPPLRERRDDIEPLASAILERL
ARDNGQPPARLQAGALLALQGHDFPGNVRELENLLERAHTLCDNRLIERHDLRLASNSAYPAIAPGPGNVIDLEAHLQAI
ERRMLLQALEQTRWNRTAAARRLSLSLRSMRYRLKKLGLD

Nucleotide

• Length: 1323 bp

>NTDB_id=140676 TO66_RS27000 WP_044465138.1 5938070..5939392(+) (pilR) [Pseudomonas sp. MRSN 12121 strain MRSN12121]
ATGGGTCCACGACAGAAAGTCCTGATCGTCGATGACGACCCAGGCACCCGCGAATATCTGGAAATCAGCCTCGGCCGGAT
GCGGCGCCATACCCGTAGCGTCTGCACCCTGGGCGAAGCCCGGCGCTGCCTGGAGCGTGAAGGTTTCGACCTGTGCCTGA
GCGACCTGCACCTGCCCGACGGTACGGGGCTGGAACTGCTGGAACACATCCGGCACCAGCAATTGCCCACATCGCTGGCG
ATCCTCAGCGCCTGTGCACTCCAGGAAACCGCTGCCCAGGCCCTACAGGCCGGCGCCATCGACGTTCTGAGCAAACCCGT
GCCCCTGGCCCGCTTGCACAAACTGCTGAACGACATCCGGCCCGAGGCGATCTCCTTCGCTAGCCGTACGCTGCTTGGCG
ACTCGGCGCCGATGCAGGCGCTGCGTGGCCAGATCGGCAAGCTGGCCGGCAGCCGGGCCGCGATCTACATCAGCGGCGAA
TCCGGAAGTGGCAAAGAGCTGGTCGCCCGCGCGCTCCATGACCAGGGCGCACGGGCCAGCCGGGCCTTCGTGGCGGTCAA
CTGCGGGGCCATTCCGGCGGAACTGATGGAAAGCGAGTTCTTCGGCCATCGCAAAGGCAGCTTCAGTGGCGCCGTCGAAG
ACCACCCCGGCCTGTTCCAGGCAGCGCACGGCGGCACGCTGTTTCTCGACGAGGTAGCCGACCTGCCATTGGCGATGCAG
GTCAAACTGCTGCGCGCACTGCAACAGAAGGCGGTGCGCCGCGTCGGCGGGCACCAGGAGGTCCAGGTCGATGTGCGCAT
TCTCTGCGCCACCCACAAGCCGCTGCTGGCAGAAGTGCAGGCCGGGCGCTTTCGCCAGGACCTCTATTACCGCCTGAACG
TGATCGAGCTGCCTGTCCCGCCTTTGCGGGAGCGCCGGGACGATATCGAACCGCTGGCCAGCGCCATCCTCGAACGCCTG
GCACGCGACAATGGCCAGCCACCGGCACGGCTCCAGGCTGGAGCGCTGCTGGCTCTCCAGGGGCATGACTTTCCCGGCAA
TGTGCGCGAACTGGAAAACCTGCTCGAACGGGCACACACCCTGTGCGACAACCGGCTGATCGAACGCCACGACCTGCGCC
TCGCATCCAATAGCGCATACCCGGCCATCGCGCCCGGGCCGGGGAACGTCATCGATCTTGAAGCACACCTGCAAGCGATC
GAGCGCCGCATGCTCCTCCAGGCCCTGGAGCAGACCCGCTGGAACCGCACGGCGGCGGCCCGGCGTCTGAGCCTGTCGTT
GCGTTCGATGCGCTATCGGCTGAAGAAACTGGGGCTGGACTAA

Domains

Predicted by InterproScan.

• Sigma-54 interaction domain (Sigma54_activat) (132-297)

• Bacterial regulatory protein, Fis family (HTH_8) (398-437)

• Response regulator receiver domain (Response_reg) (7-116)

3D structure

• AlphaFold DB: A0A0C5EBK8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	64.108	100	0.645
pilR	Acinetobacter baumannii strain A118	43.167	100	0.452