Detailed information NTG0140666

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: TO66_RS08875
• Genome accession: NZ_CP010892
• Coordinates: 1954786..1957017 (+)
• Length: 743 a.a.
• NCBI ID: WP_044461982.1
• Uniprot ID: A0A0C5DZ22
• Organism: Pseudomonas sp. MRSN 12121 strain MRSN12121
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1949786..1962017

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TO66_RS08850 (TO66_08840)	-	1950908..1951567 (+)	660	WP_044461977.1	transglutaminase family protein	-
TO66_RS08855 (TO66_08845)	-	1951610..1952233 (+)	624	WP_044461978.1	glutathione S-transferase family protein	-
TO66_RS08860 (TO66_08850)	-	1952366..1953298 (+)	933	WP_044461979.1	ABC transporter ATP-binding protein	-
TO66_RS08865 (TO66_08855)	-	1953295..1954074 (+)	780	WP_044461980.1	ABC transporter permease	-
TO66_RS08870 (TO66_08860)	-	1954123..1954638 (-)	516	WP_044461981.1	DUF2062 domain-containing protein	-
TO66_RS08875 (TO66_08865)	comA	1954786..1957017 (+)	2232	WP_044461982.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
TO66_RS08880 (TO66_08870)	exbB	1957120..1957755 (+)	636	WP_044461983.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
TO66_RS08885 (TO66_08875)	-	1957752..1958180 (+)	429	WP_044461984.1	biopolymer transporter ExbD	-
TO66_RS08890 (TO66_08880)	lpxK	1958180..1959190 (+)	1011	WP_044461985.1	tetraacyldisaccharide 4'-kinase	-
TO66_RS08895 (TO66_08885)	-	1959215..1959400 (+)	186	WP_044461986.1	Trm112 family protein	-
TO66_RS08900 (TO66_08890)	kdsB	1959397..1960161 (+)	765	WP_044461987.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
TO66_RS08905 (TO66_08895)	-	1960161..1960625 (+)	465	WP_044461988.1	low molecular weight protein-tyrosine-phosphatase	-
TO66_RS08910 (TO66_08900)	murB	1960622..1961641 (+)	1020	WP_044461989.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 81600.99 Da
• Isoelectric Point: 10.7527

>NTDB_id=140666 TO66_RS08875 WP_044461982.1 1954786..1957017(+) (comA) [Pseudomonas sp. MRSN 12121 strain MRSN12121]
MRIAMLALATGLLTLRFLPVLPAFGWLVALVVLALMLLPFRSYPVALFLFGLVWACASAQRALDDRLSEPLDGQTRWLEG
RVVGLPQQADGILRFELEDAQARRGPIPRRLRLAWYGGPPLHSGERWRLAVKLKRPLGLVNLQAFDHEAWLLAQRIGATG
TVKDGQRLVATEGGWRARIRQRLLQVEAHGRGGGLAALVLGDGSGLSREDWRVLQDTGTVHLMVISGQHISLLAAVMYAL
VAGLARYGLWPMRWPWLPWACGLAFASALGYGLLAGFDVPVRRACVMVALVLIWRLRFRHLGAWWPFLLALNAVLLFEPL
ASLQPGFWLSFTAVAVLILVFGGRLGGWRWWQSWTRIQWLIAIGLCPVLLALGLPISLSGPLANLLAEPWISLLVLPPAL
LGTLFLAVPWLGEGLLWLAGGLLDLLFRGLGLLAARWPAWIAPDIPLWAWGISALGALLLLLPAGVPLRPLGWPMLLLMV
FPPKNTLPYGLAQVWQLDVGQGLAVVIRTREHALLYDAGPRFGDSDLGERVVLPSLRKLGIERLDLMLLSHADADHAGGA
DAVLRGLPVARLLGGDPEGLPAHLSAQPCASGEQWQWDGVRFSLWQWSQARTGNQKSCVLQVEARGERLLLTGDIDAQAE
RALLDTPLAVRTHWLQAPHHGSRSSSSVALLKALAPSAVLISRGHGNGFGHPHPQVVERYRQQGTTLYDSARHGALQVML
GTYAEPVSLRAQRRFWRKWPLSP

Nucleotide

• Length: 2232 bp

>NTDB_id=140666 TO66_RS08875 WP_044461982.1 1954786..1957017(+) (comA) [Pseudomonas sp. MRSN 12121 strain MRSN12121]
ATGCGTATCGCCATGCTGGCATTGGCAACGGGGTTGCTGACCCTGCGTTTCCTGCCGGTGCTGCCGGCCTTCGGATGGCT
GGTCGCGCTGGTGGTCCTGGCCCTGATGCTGCTGCCGTTTCGCAGCTATCCCGTGGCCTTGTTCCTGTTCGGGCTGGTCT
GGGCTTGCGCCAGCGCGCAACGCGCCCTGGATGATCGCCTGTCGGAACCGCTCGACGGCCAGACCCGCTGGCTCGAGGGC
CGGGTCGTGGGGCTGCCGCAACAGGCCGACGGCATCCTGCGCTTCGAACTGGAAGACGCGCAGGCGCGGCGCGGGCCGAT
TCCCCGGCGCCTGCGCCTGGCCTGGTACGGCGGACCACCGCTGCACAGCGGCGAACGCTGGCGCCTGGCGGTGAAGCTCA
AGCGGCCGCTCGGCCTGGTCAACCTGCAGGCCTTCGATCATGAGGCCTGGCTGCTGGCCCAGCGCATCGGTGCCACGGGG
ACGGTCAAGGATGGGCAGCGGCTGGTCGCCACCGAGGGCGGCTGGCGGGCACGCATTCGCCAGCGCTTGCTGCAAGTCGA
GGCCCATGGGCGCGGCGGTGGCCTGGCGGCCCTGGTACTGGGCGACGGCTCGGGGCTCAGCCGGGAAGACTGGCGGGTGT
TGCAGGATACGGGGACCGTGCACCTGATGGTGATATCCGGGCAGCACATCAGTTTGCTGGCTGCCGTGATGTACGCCCTG
GTGGCCGGGCTGGCCCGTTATGGCCTGTGGCCCATGCGCTGGCCCTGGCTGCCCTGGGCGTGCGGGCTGGCCTTCGCCTC
GGCCCTGGGCTATGGCCTGCTCGCGGGGTTCGACGTGCCGGTGCGCCGCGCCTGCGTGATGGTCGCCCTGGTGCTGATCT
GGCGCCTGCGCTTTCGTCACCTGGGGGCCTGGTGGCCATTCCTGCTGGCGCTGAATGCCGTGCTGCTGTTCGAGCCGCTG
GCCAGCCTGCAACCGGGATTCTGGTTGTCCTTTACCGCGGTGGCGGTGTTGATTCTGGTTTTTGGCGGGCGCCTGGGCGG
CTGGCGCTGGTGGCAATCCTGGACCCGCATCCAGTGGCTGATCGCCATTGGCCTGTGCCCGGTACTGCTGGCGCTGGGGT
TGCCCATCAGCCTCAGCGGGCCCCTGGCCAATCTGTTGGCGGAGCCTTGGATCAGCCTGTTGGTGCTGCCGCCGGCATTG
CTCGGGACCTTGTTCCTGGCAGTGCCTTGGCTGGGCGAGGGGTTGTTGTGGCTGGCGGGCGGTTTGCTCGACCTGTTGTT
CCGCGGCCTTGGCCTGCTGGCGGCTCGATGGCCCGCCTGGATAGCCCCGGACATACCGCTCTGGGCCTGGGGCATCAGCG
CCCTGGGGGCCTTGCTGCTGTTGCTGCCCGCCGGTGTACCGCTGCGGCCGCTGGGCTGGCCGATGTTGCTGCTGATGGTG
TTTCCACCGAAAAACACGCTGCCTTATGGCCTGGCGCAGGTCTGGCAACTGGATGTCGGGCAGGGGCTGGCGGTGGTGAT
TCGCACCCGGGAGCACGCACTGCTGTACGACGCCGGCCCGCGTTTCGGCGATTCCGACCTGGGGGAGCGCGTGGTGCTGC
CGTCGTTGCGCAAGCTGGGCATCGAGCGCCTCGACCTGATGTTGCTCAGCCACGCCGATGCCGACCACGCCGGCGGGGCC
GACGCTGTCCTGCGTGGGTTGCCAGTGGCCAGGCTGCTGGGCGGCGACCCCGAGGGCTTGCCGGCCCATCTGTCGGCGCA
ACCTTGTGCCAGCGGCGAGCAGTGGCAATGGGACGGCGTGCGCTTTTCCCTGTGGCAATGGTCGCAGGCGCGGACCGGCA
ACCAGAAATCCTGCGTGCTGCAGGTCGAAGCCAGGGGCGAGCGCCTGCTGCTGACCGGGGATATCGACGCCCAGGCCGAG
CGCGCCCTGCTGGATACGCCGCTGGCCGTCCGGACCCACTGGCTGCAGGCACCGCACCATGGCAGCCGCAGTTCGTCGTC
GGTGGCCCTGCTCAAGGCGCTGGCACCCTCGGCGGTGCTGATTTCCCGCGGGCATGGCAATGGTTTCGGGCATCCGCACC
CGCAGGTCGTCGAACGTTATCGCCAGCAGGGCACCACGCTTTACGACAGCGCGCGGCATGGCGCGCTGCAAGTGATGCTG
GGTACCTACGCCGAACCCGTGAGCCTGCGGGCGCAGCGGCGCTTTTGGCGCAAATGGCCACTATCTCCTTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (498-685)

• Competence protein (Competence) (198-463)

• Domain of unknown function (DUF4131) (DUF4131) (20-167)

3D structure

• AlphaFold DB: A0A0C5DZ22

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	64.395	96.77	0.623