Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   VAA049_RS15815 Genome accession   NZ_CP010811
Coordinates   3457428..3458039 (+) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae strain 1154-74     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3452428..3463039
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VAA049_RS15795 (VAA049_3103) - 3452764..3453681 (-) 918 WP_000271070.1 ABC transporter ATP-binding protein -
  VAA049_RS15800 (VAA049_3104) - 3454062..3455708 (-) 1647 WP_046122227.1 SulP family inorganic anion transporter -
  VAA049_RS15805 (VAA049_3105) can 3455856..3456524 (+) 669 WP_001114117.1 carbonate dehydratase -
  VAA049_RS15810 (VAA049_3106) hpt 3456599..3457132 (-) 534 WP_000683351.1 hypoxanthine phosphoribosyltransferase -
  VAA049_RS15815 (VAA049_3107) hapR 3457428..3458039 (+) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  VAA049_RS15820 (VAA049_3108) rsmI 3458249..3459115 (-) 867 WP_000131549.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  VAA049_RS15825 (VAA049_3109) - 3459185..3460990 (+) 1806 WP_001015477.1 penicillin-binding protein activator -
  VAA049_RS15830 (VAA049_3110) - 3460977..3461345 (+) 369 WP_001893625.1 YraN family protein -
  VAA049_RS15835 (VAA049_3111) - 3461349..3461939 (+) 591 WP_000887295.1 phosphoheptose isomerase -
  VAA049_RS15840 (VAA049_3112) - 3461942..3462511 (+) 570 WP_002043114.1 BON domain-containing protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=139958 VAA049_RS15815 WP_000340100.1 3457428..3458039(+) (hapR) [Vibrio cholerae strain 1154-74]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=139958 VAA049_RS15815 WP_000340100.1 3457428..3458039(+) (hapR) [Vibrio cholerae strain 1154-74]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAACTTCTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGTTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709

Multiple sequence alignment