Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   APQ13_RS05545 Genome accession   NZ_CP013237
Coordinates   1165088..1165729 (-) Length   213 a.a.
NCBI ID   WP_002263036.1    Uniprot ID   -
Organism   Streptococcus mutans strain NG8 isolate Dental Plaque     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1160088..1170729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APQ13_RS05525 (APQ13_05520) - 1161527..1162273 (-) 747 WP_002264395.1 DeoR/GlpR family DNA-binding transcription regulator -
  APQ13_RS05530 (APQ13_05525) - 1162404..1163180 (+) 777 WP_002266348.1 glycyl-radical enzyme activating protein -
  APQ13_RS05535 (APQ13_05530) - 1163259..1163645 (-) 387 WP_002263034.1 S1 RNA-binding domain-containing protein -
  APQ13_RS05540 (APQ13_05535) - 1163629..1165044 (-) 1416 WP_002273627.1 Cof-type HAD-IIB family hydrolase -
  APQ13_RS05545 (APQ13_05540) vraR 1165088..1165729 (-) 642 WP_002263036.1 response regulator transcription factor Regulator
  APQ13_RS05550 (APQ13_05545) - 1165722..1166726 (-) 1005 WP_002272573.1 sensor histidine kinase -
  APQ13_RS05555 (APQ13_05550) liaF 1166723..1167418 (-) 696 WP_002263038.1 cell wall-active antibiotics response protein LiaF -
  APQ13_RS05560 (APQ13_05555) pknB 1167859..1169709 (-) 1851 WP_002263039.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  APQ13_RS05565 (APQ13_05560) - 1169706..1170449 (-) 744 WP_002263040.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23824.40 Da        Isoelectric Point: 4.8864

>NTDB_id=139686 APQ13_RS05545 WP_002263036.1 1165088..1165729(-) (vraR) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MSKTKVILVDDHEMVRLGLKSFLNLQDNVEVIGEASNGRQGIDLALKLKPDVVVMDLVMPEMDGVEATLELLKDWKEAKI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVAKGDLAIETEVDKKIKDHHNNPDLHEDLTARERDILALLA
KGYDNQTIADELFISLKTVKTHVSNILSKLQVDDRTQAVVYAFQHHLVPQDEN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=139686 APQ13_RS05545 WP_002263036.1 1165088..1165729(-) (vraR) [Streptococcus mutans strain NG8 isolate Dental Plaque]
ATGAGTAAAACAAAAGTTATACTGGTTGATGATCATGAAATGGTTCGATTGGGTTTGAAAAGTTTTCTTAATTTACAAGA
TAATGTAGAAGTTATCGGTGAGGCTAGCAATGGCCGTCAAGGTATTGACTTGGCTTTAAAATTAAAACCAGACGTTGTTG
TCATGGACTTGGTTATGCCAGAAATGGATGGTGTAGAAGCCACTCTTGAACTTCTAAAAGATTGGAAAGAAGCCAAAATT
CTAGTTTTAACCAGTTATTTAGATAACGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTGAAAAC
TTCCAGTGCAGCTGAAATTTTGAATGCCATTCAAAAAGTAGCTAAGGGAGATTTAGCGATTGAAACAGAAGTTGATAAGA
AAATCAAGGATCATCATAATAATCCTGATTTGCATGAAGATTTAACAGCGCGTGAACGAGACATTTTGGCTTTACTTGCT
AAGGGTTATGATAACCAAACGATTGCTGATGAGCTTTTCATTTCTTTGAAGACTGTCAAAACACATGTTTCTAATATCTT
ATCGAAATTACAAGTTGATGATCGGACCCAAGCCGTTGTCTATGCTTTTCAGCATCATTTAGTGCCACAGGACGAAAATT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.22

96.244

0.493
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376

Multiple sequence alignment