Detailed information NTG0139516

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: HSISS4_RS07790
• Genome accession: NZ_CP013216
• Coordinates: 1719321..1721426 (-)
• Length: 701 a.a.
• NCBI ID: WP_021143707.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain HSISS4
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1714321..1726426

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HSISS4_RS07760 (HSISS4_01517)	ccrZ	1714685..1715476 (-)	792	WP_002884270.1	cell cycle regulator CcrZ	-
HSISS4_RS07765 (HSISS4_01518)	pptB	1715534..1716568 (-)	1035	WP_418080400.1	ABC transporter permease	Regulator
HSISS4_RS07770 (HSISS4_01519)	pptA	1716568..1717299 (-)	732	WP_021143710.1	ABC transporter ATP-binding protein	Regulator
HSISS4_RS07775 (HSISS4_01520)	-	1717364..1717783 (+)	420	WP_002891660.1	HIT family protein	-
HSISS4_RS07780 (HSISS4_01521)	-	1717780..1718079 (+)	300	WP_021143709.1	hypothetical protein	-
HSISS4_RS07785 (HSISS4_01522)	-	1718111..1718887 (-)	777	WP_021143708.1	FxLYD domain-containing protein	-
HSISS4_RS07790 (HSISS4_01523)	clpE	1719321..1721426 (-)	2106	WP_021143707.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
HSISS4_RS07795 (HSISS4_01524)	-	1722127..1722381 (-)	255	WP_021143706.1	Txe/YoeB family addiction module toxin	-
HSISS4_RS07800 (HSISS4_01525)	-	1722385..1722639 (-)	255	WP_042762439.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
HSISS4_RS07805 (HSISS4_01526)	-	1722781..1723872 (-)	1092	WP_021143704.1	nucleotidyltransferase	-
HSISS4_RS07810 (HSISS4_01527)	-	1723879..1724619 (-)	741	WP_021143703.1	class I SAM-dependent DNA methyltransferase	-
HSISS4_RS07815 (HSISS4_01528)	rsfS	1724824..1725177 (-)	354	WP_014632696.1	ribosome silencing factor	-
HSISS4_RS07820 (HSISS4_01529)	yqeK	1725200..1725790 (-)	591	WP_021143702.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
HSISS4_RS07825 (HSISS4_01530)	-	1725787..1726419 (-)	633	WP_021143701.1	nicotinate-nucleotide adenylyltransferase	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77294.28 Da
• Isoelectric Point: 4.7671

>NTDB_id=139516 HSISS4_RS07790 WP_021143707.1 1719321..1721426(-) (clpE) [Streptococcus salivarius strain HSISS4]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQQQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEAEKAKQEVAAAKEDYEAALNAKVRIEELEKKIANHTADLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2106 bp

>NTDB_id=139516 HSISS4_RS07790 WP_021143707.1 1719321..1721426(-) (clpE) [Streptococcus salivarius strain HSISS4]
ATGAACAACAACTTTAACAATATGGACGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCGATTTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACAACAAGGTAAAGGACCTAAACAAGATGGTATTCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACCAAGAATAACCCAGTCCTTGTCGGGGATGCTGGGGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCTC
AAGCCATCGTCAATGGTGATGTCCCAGCTGCTATCAAGAATAAAGAAATCATTTCAATTGATATTTCTGGACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAACGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGTGATGGTCAAGGGTCTAAAGGTCTTGCTGATATCT
TGAAACCAGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AATGCTGCCCTAGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTGCTGAAGATACTTTCAAGATTCTCCAAGG
TATCCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTTTTGAAGGCAGCGGTAGATTTCTCTGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATTGAAGCTGAAAAAGCTAAACAAGAAGTTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCATACAGCAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATCCCAGTATCGCAAATGGGAGCAACTGAT
ATCGAACGTTTGAAAGATATGGGCCACCGTTTGCAAACTAAAGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATTGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGTACTAAAGATGCCATTATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTTCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTCATCA
CCCTTCTCCTCCAAGTTTTGGACGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGATTTGGTTACGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGACGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGATAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (441-601)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-678)

• AAA lid domain (AAA_lid_9) (257-353)

• ATPase family associated with various cellular activities (AAA) (AAA) (116-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.293	100	0.474
clpC	Lactococcus lactis subsp. cremoris KW2	49.002	92.867	0.455
clpE	Streptococcus pneumoniae D39	49.224	91.869	0.452
clpE	Streptococcus pneumoniae R6	49.224	91.869	0.452
clpE	Streptococcus pneumoniae TIGR4	49.224	91.869	0.452
clpE	Streptococcus pneumoniae Rx1	49.224	91.869	0.452
clpC	Bacillus subtilis subsp. subtilis str. 168	46.13	92.154	0.425
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.089	92.867	0.391
clpC	Streptococcus pneumoniae Rx1	43.76	88.017	0.385
clpC	Streptococcus pneumoniae D39	43.76	88.017	0.385
clpC	Streptococcus pneumoniae TIGR4	43.76	88.017	0.385
clpC	Streptococcus thermophilus LMD-9	43.598	88.017	0.384
clpC	Streptococcus thermophilus LMG 18311	43.387	88.445	0.384
clpC	Streptococcus mutans UA159	42.308	89.016	0.377