Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   SAST39_RS08365 Genome accession   NZ_CP012970
Coordinates   1697944..1699206 (-) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain ST20130939     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1692944..1704206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAST39_RS08340 (SAST39_01721) - 1693142..1693810 (-) 669 WP_000805950.1 uroporphyrinogen-III synthase -
  SAST39_RS08345 (SAST39_03808) hemC 1693832..1694758 (-) 927 WP_001230226.1 hydroxymethylbilane synthase -
  SAST39_RS08350 (SAST39_01723) ccsA 1694800..1695615 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  SAST39_RS08355 (SAST39_01724) hemA 1695637..1696983 (-) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  SAST39_RS08360 (SAST39_01725) yihA 1697200..1697790 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  SAST39_RS08365 (SAST39_01726) clpX 1697944..1699206 (-) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  SAST39_RS08370 (SAST39_01727) tig 1699357..1700658 (-) 1302 WP_000127573.1 trigger factor -
  SAST39_RS08375 - 1700706..1700816 (-) 111 WP_001790560.1 hypothetical protein -
  SAST39_RS08380 (SAST39_01728) - 1700821..1701750 (-) 930 WP_001280022.1 hypothetical protein -
  SAST39_RS08385 (SAST39_01729) - 1701769..1702377 (-) 609 WP_000032656.1 NUDIX domain-containing protein -
  SAST39_RS08395 (SAST39_01730) rplT 1702519..1702875 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  SAST39_RS08400 (SAST39_01731) rpmI 1702922..1703122 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  SAST39_RS08405 (SAST39_03333) infC 1703151..1703678 (-) 528 WP_062911945.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=137835 SAST39_RS08365 WP_000472293.1 1697944..1699206(-) (clpX) [Staphylococcus aureus strain ST20130939]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=137835 SAST39_RS08365 WP_000472293.1 1697944..1699206(-) (clpX) [Staphylococcus aureus strain ST20130939]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACCTTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGAGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531

Multiple sequence alignment