Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   ACT75_RS05460 Genome accession   NZ_CP012959
Coordinates   1136453..1137262 (+) Length   269 a.a.
NCBI ID   WP_005549310.1    Uniprot ID   A0A5D0ENJ4
Organism   Aggregatibacter actinomycetemcomitans strain 624     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1131453..1142262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACT75_RS05450 (ACT75_05445) - 1132812..1133657 (-) 846 WP_005540242.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  ACT75_RS05455 (ACT75_05450) - 1133752..1136319 (-) 2568 WP_005549313.1 penicillin-binding protein 1A -
  ACT75_RS05460 (ACT75_05455) comA 1136453..1137262 (+) 810 WP_005549310.1 hypothetical protein Machinery gene
  ACT75_RS05465 (ACT75_05460) - 1137273..1137791 (+) 519 WP_005549308.1 PilN domain-containing protein -
  ACT75_RS05470 (ACT75_05465) - 1137788..1138312 (+) 525 WP_005543969.1 hypothetical protein -
  ACT75_RS05475 (ACT75_05470) - 1138312..1138704 (+) 393 WP_005549304.1 hypothetical protein -
  ACT75_RS05480 (ACT75_05475) comE 1138725..1140134 (+) 1410 WP_005554456.1 type IV pilus secretin PilQ Machinery gene
  ACT75_RS05485 (ACT75_05480) aroK 1140348..1140875 (+) 528 WP_005543963.1 shikimate kinase AroK -
  ACT75_RS05490 (ACT75_05485) aroB 1140899..1141987 (+) 1089 WP_005543960.1 3-dehydroquinate synthase -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 31305.90 Da        Isoelectric Point: 5.9306

>NTDB_id=137731 ACT75_RS05460 WP_005549310.1 1136453..1137262(+) (comA) [Aggregatibacter actinomycetemcomitans strain 624]
MFIRHIPTLQVGLWCRGETIDAAWIDPQNQPHFLRLGELELMELTSHLNRRFNHPRKKLAYKFITAIMPHQIWQKTLILP
HNLNLQECEQQCHFSLTNELPIPTEEVWYDYAATPLKQGFRLDIFAIRQQIATEYLQQLIPLQIDVLDNAAKAMLRAAEY
FLGHALPNNAVFLYQDETGLLAVQHKLQQTQTLFQTPGNLTALLAQYCQRYEEEPMQVFYYQAEKDAQAIPQSWHAIETE
LPFIALGNALWQRETPLKSTALFDADHNI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=137731 ACT75_RS05460 WP_005549310.1 1136453..1137262(+) (comA) [Aggregatibacter actinomycetemcomitans strain 624]
ATGTTTATTAGACACATTCCCACACTGCAAGTCGGTCTTTGGTGCCGTGGAGAAACCATCGACGCAGCGTGGATCGACCC
GCAAAATCAACCGCACTTTTTGCGCCTCGGCGAACTGGAATTAATGGAACTGACAAGCCATTTAAACCGTCGTTTTAACC
ATCCGCGCAAAAAATTAGCCTACAAATTTATTACCGCCATCATGCCCCATCAAATCTGGCAGAAAACCTTGATTTTGCCC
CATAACCTGAACCTTCAGGAATGTGAGCAACAGTGCCATTTCAGCTTAACCAACGAGCTGCCGATTCCCACCGAAGAGGT
GTGGTATGACTACGCCGCCACACCGTTAAAACAGGGCTTTCGGTTAGATATTTTTGCCATTAGACAACAAATCGCCACAG
AATATTTGCAACAACTTATACCTTTACAAATTGACGTGTTGGACAACGCGGCAAAGGCGATGTTACGCGCGGCGGAATAT
TTTTTGGGGCACGCCTTGCCAAATAACGCCGTGTTTTTATATCAGGACGAAACGGGCTTGCTGGCGGTACAACACAAATT
ACAGCAAACCCAAACGCTGTTCCAAACGCCGGGAAACCTAACCGCACTTTTGGCGCAATATTGCCAACGTTATGAAGAAG
AACCGATGCAGGTGTTCTATTATCAAGCCGAAAAAGACGCACAGGCGATACCGCAAAGCTGGCACGCCATTGAAACCGAG
CTACCGTTCATCGCGTTAGGTAACGCCTTGTGGCAACGGGAAACGCCGTTGAAATCCACCGCACTTTTTGATGCCGACCA
CAACATTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5D0ENJ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Haemophilus influenzae Rd KW20

40.927

96.283

0.394
  comA Haemophilus influenzae 86-028NP

40.927

96.283

0.394

Multiple sequence alignment