Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   ACT74_RS08640 Genome accession   NZ_CP012958
Coordinates   1797086..1797895 (-) Length   269 a.a.
NCBI ID   WP_005544971.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain VT1169     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1792086..1802895
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACT74_RS08610 (ACT74_08610) aroB 1792362..1793450 (-) 1089 WP_005569125.1 3-dehydroquinate synthase -
  ACT74_RS08615 (ACT74_08615) aroK 1793474..1794001 (-) 528 WP_005555432.1 shikimate kinase AroK -
  ACT74_RS08620 (ACT74_08620) comE 1794215..1795624 (-) 1410 WP_050846294.1 type IV pilus secretin PilQ Machinery gene
  ACT74_RS08625 (ACT74_08625) - 1795644..1796036 (-) 393 WP_005544975.1 hypothetical protein -
  ACT74_RS08630 (ACT74_08630) - 1796036..1796560 (-) 525 WP_005543969.1 hypothetical protein -
  ACT74_RS08635 (ACT74_08635) - 1796557..1797075 (-) 519 WP_005544973.1 PilN domain-containing protein -
  ACT74_RS08640 (ACT74_08640) comA 1797086..1797895 (-) 810 WP_005544971.1 hypothetical protein Machinery gene
  ACT74_RS08645 (ACT74_08645) - 1798029..1800596 (+) 2568 WP_005566815.1 penicillin-binding protein 1A -
  ACT74_RS08650 (ACT74_08650) - 1800691..1801536 (+) 846 WP_005544967.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 31326.94 Da        Isoelectric Point: 6.1096

>NTDB_id=137701 ACT74_RS08640 WP_005544971.1 1797086..1797895(-) (comA) [Aggregatibacter actinomycetemcomitans strain VT1169]
MFIRHIPTLQVGLWCRGETIDAAWIDPQNQPHFLRLGELELMELTSHLNRRFNHPRKKLAYKFITAIMPHQIWQKTLILP
HNLNLQECEQQCHFSLTNELPIPTEEVWYDYAATPLKQGFRLDIFAIRQQIATEYLQQLMPLQIDVLDNAAKAMLRAAEY
FLGHALPNNAVFLYQDETGLLAVQHKLQQTQTLFQTQGNLTALLAQYCQRYAEEPMQVFYYQTEKDAQAIPQSWHAIETE
LPFIALGNALWQRETPLKSTALFDADHNI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=137701 ACT74_RS08640 WP_005544971.1 1797086..1797895(-) (comA) [Aggregatibacter actinomycetemcomitans strain VT1169]
ATGTTTATTAGACACATTCCCACACTGCAAGTCGGTCTTTGGTGCCGTGGAGAAACCATCGACGCAGCGTGGATCGACCC
GCAAAATCAACCGCACTTTTTGCGCCTCGGCGAACTGGAATTAATGGAACTGACAAGCCATTTAAACCGTCGTTTTAACC
ATCCGCGCAAAAAATTAGCCTACAAATTTATTACCGCCATCATGCCCCATCAAATCTGGCAGAAAACCTTGATTTTGCCC
CATAACCTGAACCTTCAGGAATGTGAGCAACAGTGCCATTTCAGCTTAACCAACGAGCTGCCGATTCCCACCGAAGAGGT
GTGGTATGACTACGCAGCCACACCGTTAAAACAGGGCTTTCGGTTAGATATTTTTGCCATTAGACAACAAATCGCCACAG
AATATTTGCAACAACTTATGCCTTTACAAATTGACGTGTTAGACAACGCGGCAAAAGCGATGTTACGTGCGGCGGAATAT
TTTTTGGGGCACGCCTTGCCAAATAACGCCGTGTTTTTATATCAGGACGAAACGGGCTTGCTGGCGGTACAACACAAATT
ACAGCAAACCCAAACGCTGTTCCAAACGCAGGGAAACCTGACCGCACTTTTGGCGCAATATTGCCAACGTTATGCAGAAG
AACCGATGCAGGTGTTCTATTATCAAACCGAAAAAGACGCACAGGCGATACCGCAAAGCTGGCACGCCATTGAAACCGAG
CTACCGTTCATCGCGTTAGGTAACGCCTTGTGGCAACGGGAAACGCCGTTGAAATCCACCGCACTTTTTGACGCCGACCA
CAACATTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Haemophilus influenzae Rd KW20

40.541

96.283

0.39
  comA Haemophilus influenzae 86-028NP

40.541

96.283

0.39

Multiple sequence alignment