Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   ACT74_RS07015 Genome accession   NZ_CP012958
Coordinates   1494676..1495365 (+) Length   229 a.a.
NCBI ID   WP_005547547.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain VT1169     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1489676..1500365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACT74_RS06990 (ACT74_06985) nanQ 1489957..1490427 (+) 471 WP_005547536.1 N-acetylneuraminate anomerase -
  ACT74_RS06995 (ACT74_06990) ampD 1490901..1491455 (-) 555 WP_005567973.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  ACT74_RS07000 (ACT74_06995) pilA 1491577..1492029 (+) 453 WP_005586498.1 pilin Machinery gene
  ACT74_RS07005 (ACT74_07000) - 1492056..1493463 (+) 1408 Protein_1378 GspE/PulE family protein -
  ACT74_RS07010 (ACT74_07005) pilC 1493456..1494679 (+) 1224 WP_005567968.1 type II secretion system F family protein Machinery gene
  ACT74_RS07015 (ACT74_07010) pilD 1494676..1495365 (+) 690 WP_005547547.1 prepilin peptidase Machinery gene
  ACT74_RS07020 (ACT74_07015) coaE 1495415..1496038 (+) 624 WP_005547548.1 dephospho-CoA kinase -
  ACT74_RS07025 (ACT74_07020) yacG 1496028..1496240 (+) 213 WP_005567966.1 DNA gyrase inhibitor YacG -
  ACT74_RS07030 (ACT74_07025) - 1496240..1496512 (+) 273 WP_005547552.1 GNAT family N-acetyltransferase -
  ACT74_RS07035 (ACT74_07030) - 1496909..1498282 (+) 1374 WP_005547554.1 alanine/glycine:cation symporter family protein -
  ACT74_RS07040 (ACT74_07035) raiA 1498510..1498833 (+) 324 WP_005540708.1 ribosome-associated translation inhibitor RaiA -
  ACT74_RS07045 (ACT74_07040) - 1498982..1499536 (+) 555 WP_005540709.1 DUF5358 domain-containing protein -
  ACT74_RS11480 - 1499814..1499976 (-) 163 Protein_1387 phosphoribosylformylglycinamidine synthase subunit PurQ -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26018.72 Da        Isoelectric Point: 8.2297

>NTDB_id=137693 ACT74_RS07015 WP_005547547.1 1494676..1495365(+) (pilD) [Aggregatibacter actinomycetemcomitans strain VT1169]
MMWLLFLLGGALCGWRVHRYVEHFADNLSREVHAAYTEIYPQNPPHFTAEKSILKPLKRHFSAPLYSLLFTLLFIICYAI
NEPLQALCFALYGALLIAISLVDWHYRLISPALCQALFTLGLGAAYWQIGTLTLEQSLQSAVVFFGVFYAIYHAAKWYYR
QEALGRGDYWLALGLGVFLPAHQFPVFLFLACFFGLLYAAYAKYQHRTLNAVPFGPFMSLAGVVCLLLN

Nucleotide


Download         Length: 690 bp        

>NTDB_id=137693 ACT74_RS07015 WP_005547547.1 1494676..1495365(+) (pilD) [Aggregatibacter actinomycetemcomitans strain VT1169]
ATGATGTGGCTACTTTTTTTGCTTGGTGGCGCACTATGCGGGTGGCGTGTTCATCGTTATGTAGAACATTTCGCCGATAA
CCTCAGCCGCGAGGTTCATGCCGCCTACACGGAAATTTACCCGCAAAACCCACCGCACTTTACAGCGGAAAAGTCGATTC
TGAAACCGCTTAAACGGCATTTTTCCGCGCCCCTTTACAGCCTTTTATTCACCTTGCTGTTCATTATTTGTTATGCCATC
AATGAACCGTTACAAGCCCTATGCTTTGCCCTTTATGGCGCCTTATTAATTGCCATTTCCCTAGTGGATTGGCACTATCG
CTTGATTTCACCCGCCTTATGCCAAGCCTTGTTTACCCTCGGTTTAGGCGCGGCATACTGGCAAATCGGCACATTAACAT
TGGAGCAAAGCCTGCAAAGTGCGGTTGTTTTTTTCGGTGTTTTTTATGCCATCTACCACGCCGCAAAATGGTACTACCGA
CAAGAAGCTCTCGGACGCGGCGATTATTGGTTGGCACTGGGCTTAGGCGTTTTTCTCCCGGCACACCAATTTCCTGTTTT
TTTATTCCTCGCCTGCTTTTTCGGCTTACTTTATGCTGCCTACGCCAAATACCAACATCGCACACTCAACGCCGTGCCTT
TCGGTCCCTTTATGTCCCTAGCCGGCGTGGTCTGTTTATTGCTTAATTGA

Domains

Predicted by InterProScan.

Type IV leader peptidase family (Peptidase_A24)

(94-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

39.301

100

0.393
  pilD Haemophilus influenzae Rd KW20

38.839

97.817

0.38