Detailed information NTG0137348

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SD89_RS07690
• Genome accession: NZ_CP010449
• Coordinates: 1538221..1539222 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NGAS322
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1533221..1544222

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SD89_RS07675 (SD89_07710)	thrS	1533391..1535334 (-)	1944	WP_053308556.1	threonine--tRNA ligase	-
SD89_RS07680 (SD89_07715)	-	1535756..1537090 (-)	1335	WP_053308557.1	glycosyltransferase family 4 protein	-
SD89_RS07685 (SD89_07720)	-	1537092..1538090 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
SD89_RS07690 (SD89_07725)	ccpA	1538221..1539222 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
SD89_RS07695 (SD89_07730)	-	1539396..1540481 (+)	1086	WP_053308558.1	aminopeptidase P family protein	-
SD89_RS07700 (SD89_07735)	-	1540530..1541195 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
SD89_RS07705 (SD89_07740)	-	1541206..1541583 (+)	378	WP_002985686.1	VOC family protein	-
SD89_RS07710 (SD89_07745)	-	1541728..1542654 (+)	927	WP_053308559.1	glycosyltransferase family 2 protein	-
SD89_RS07715 (SD89_07750)	-	1542865..1543548 (+)	684	WP_053308560.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=137348 SD89_RS07690 WP_002985680.1 1538221..1539222(-) (ccpA) [Streptococcus pyogenes strain NGAS322]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=137348 SD89_RS07690 WP_002985680.1 1538221..1539222(-) (ccpA) [Streptococcus pyogenes strain NGAS322]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATTATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559