Detailed information NTG0136679

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AO353_RS27675
• Genome accession: NZ_CP012830
• Coordinates: 6031673..6033943 (-)
• Length: 756 a.a.
• NCBI ID: WP_054597844.1
• Uniprot ID: A0A423H668
• Organism: Pseudomonas fluorescens strain FW300-N2E3
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 6026673..6038943

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AO353_RS27655 (AO353_27655)	trxB	6027651..6028601 (+)	951	WP_054597841.1	thioredoxin-disulfide reductase	-
AO353_RS27660 (AO353_27660)	aat	6028666..6029346 (+)	681	WP_054597842.1	leucyl/phenylalanyl-tRNA--protein transferase	-
AO353_RS27665 (AO353_27665)	-	6029405..6030112 (+)	708	WP_054597843.1	arginyltransferase	-
AO353_RS27670 (AO353_27670)	infA	6030224..6030442 (+)	219	WP_002553999.1	translation initiation factor IF-1	-
AO353_RS27675 (AO353_27675)	clpC	6031673..6033943 (-)	2271	WP_054597844.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
AO353_RS27680 (AO353_27680)	clpS	6033973..6034335 (-)	363	WP_015094394.1	ATP-dependent Clp protease adapter ClpS	-
AO353_RS27685 (AO353_27685)	cspD	6034559..6034822 (+)	264	WP_162491273.1	cold shock domain-containing protein CspD	-
AO353_RS27690 (AO353_27690)	icd	6034903..6036159 (-)	1257	WP_054597846.1	NADP-dependent isocitrate dehydrogenase	-
AO353_RS27695 (AO353_27695)	-	6036652..6038877 (+)	2226	WP_054597847.1	NADP-dependent isocitrate dehydrogenase	-

Sequence

Protein

• Length: 756 a.a.
• Molecular weight: 83444.13 Da
• Isoelectric Point: 5.9867

>NTDB_id=136679 AO353_RS27675 WP_054597844.1 6031673..6033943(-) (clpC) [Pseudomonas fluorescens strain FW300-N2E3]
MLNRELEVTLNLAFKEARSKRHEFMTVEHLLLALLDNEAAATVLRACGANLDKLKHDLQEFIDSTTPLIPLHDEDRETQP
TLGFQRVLQRAVFHVQSSGKREVTGANVLVAIFSEQESQAVFLLKQQSVARIDVVNYIAHGISKVPGHGEHSEGEQDMQD
DEGGESSSSGNPLDAYASNLNELARQGRIDPLVGREMEVERVAQILARRRKNNPLLVGEAGVGKTAIAEGLAKRIVDNQV
PDLLANSVVYSLDLGALLAGTKYRGDFEKRFKALLNELKKRPQAILFIDEIHTIIGAGAASGGVMDASNLLKPLLSSGDI
RCIGSTTFQEFRGIFEKDRALARRFQKVDVSEPSVEDTIGILRGLKGRFELHHNIEYSDEALRAAAELASRYINDRHMPD
KAIDVIDEAGAYQRLQPIEKRVKRIEVPQVEDIVAKIARIPPKHVTSSDKELLRNLERDLKLTVFGQDAAIDSLSTAIKL
SRAGLKSPDKPVGSFLFAGPTGVGKTEAARQLAKALGIELVRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTEAITKQ
PHCVLLLDEIEKAHPEVFNLLLQVMDHGTLTDNNGRKADFRNVIVIMTTNAGAETAARASIGFTHQDHSSDAMEVIKKSF
TPEFRNRLDTIIQFGRLSHEVIKSVVDKFLTELQAQLEDKRVLLEVTDAARSWLAAGGYDATMGARPMARLIQDKIKRPL
AEEILFGELAEHGGVVHIDIKDGELTFDFETTAEMA

Nucleotide

• Length: 2271 bp

>NTDB_id=136679 AO353_RS27675 WP_054597844.1 6031673..6033943(-) (clpC) [Pseudomonas fluorescens strain FW300-N2E3]
ATGTTAAACCGCGAGCTCGAAGTCACCCTCAATCTCGCCTTCAAGGAGGCGCGTTCGAAACGTCATGAGTTCATGACCGT
CGAACACCTCCTGTTGGCTCTATTGGATAATGAGGCAGCCGCCACCGTTTTGCGTGCGTGCGGCGCAAACCTCGACAAAC
TCAAGCATGACCTGCAGGAGTTCATCGACTCCACCACGCCTTTGATCCCCCTTCATGACGAGGATCGCGAAACCCAGCCA
ACCCTGGGCTTCCAGCGTGTACTGCAACGTGCTGTCTTTCATGTACAGAGCTCGGGCAAACGCGAAGTAACTGGCGCCAA
CGTGCTGGTTGCAATCTTCAGTGAGCAAGAGAGTCAGGCGGTGTTCCTGCTGAAACAGCAGAGCGTTGCACGCATTGATG
TCGTCAATTACATCGCTCATGGCATCTCGAAAGTGCCTGGGCATGGCGAACACTCTGAAGGTGAGCAAGATATGCAGGAC
GACGAGGGCGGTGAGTCTTCTTCTTCAGGCAATCCTCTGGATGCATATGCCAGCAACCTCAACGAACTGGCGCGCCAGGG
GCGTATCGACCCATTGGTCGGGCGTGAAATGGAAGTTGAGCGTGTCGCGCAGATTCTGGCGCGTCGGCGTAAAAACAATC
CGTTGCTGGTCGGCGAGGCAGGCGTGGGTAAAACCGCAATTGCCGAAGGTCTGGCCAAGCGCATTGTCGACAATCAGGTG
CCTGATCTGTTGGCCAATAGCGTGGTTTATTCGCTCGATCTGGGCGCATTACTCGCTGGGACCAAATACCGTGGCGATTT
CGAGAAACGCTTCAAGGCGTTGCTCAATGAGCTGAAAAAACGTCCGCAGGCGATCCTGTTCATCGACGAGATCCACACCA
TTATTGGTGCAGGTGCCGCCTCTGGCGGTGTCATGGATGCTTCGAACCTGCTCAAGCCGCTGCTGTCGTCGGGTGATATC
CGTTGCATCGGCTCGACCACGTTCCAGGAATTCCGTGGGATCTTCGAAAAAGACCGTGCCCTGGCTCGGCGCTTCCAGAA
GGTCGATGTGTCGGAGCCTTCGGTCGAAGACACCATTGGTATCCTGCGCGGTCTCAAGGGGCGTTTCGAGCTCCATCACA
ATATCGAATACAGTGATGAAGCCCTGCGCGCCGCTGCCGAACTGGCATCGCGCTACATCAATGACCGGCACATGCCGGAC
AAGGCCATCGACGTCATCGACGAGGCGGGCGCCTATCAGCGTCTGCAGCCGATCGAGAAGCGTGTGAAACGCATCGAAGT
GCCTCAGGTCGAGGACATCGTGGCGAAGATCGCGCGGATTCCGCCAAAACACGTCACCAGCTCCGACAAAGAGTTGCTGC
GTAACCTTGAGCGCGATCTGAAGTTGACGGTGTTCGGCCAGGATGCGGCGATTGATTCCTTGTCGACCGCGATCAAGCTG
TCCCGTGCGGGTCTGAAGTCGCCTGACAAGCCTGTCGGTTCGTTCCTGTTTGCCGGCCCTACCGGGGTCGGTAAAACCGA
AGCGGCCCGGCAACTGGCCAAGGCGCTCGGGATCGAACTGGTTCGCTTCGACATGTCCGAATACATGGAACGCCACACCG
TTTCGCGTTTGATCGGTGCACCTCCGGGGTACGTCGGGTTCGATCAGGGCGGCCTGCTGACTGAAGCGATCACCAAGCAG
CCTCATTGCGTGCTGTTGCTCGATGAAATCGAGAAGGCGCATCCGGAAGTCTTCAACCTGCTGTTGCAGGTCATGGACCA
CGGTACGCTTACCGATAACAACGGGCGCAAGGCGGATTTCCGTAACGTGATCGTCATCATGACGACCAACGCCGGTGCCG
AAACCGCAGCTCGGGCTTCTATTGGCTTCACGCATCAGGATCACTCGTCTGACGCGATGGAAGTGATCAAGAAGAGCTTC
ACGCCGGAATTCCGTAACCGTCTGGACACCATTATCCAGTTTGGTCGCCTCAGTCATGAGGTCATCAAAAGCGTGGTGGA
CAAGTTCCTTACCGAACTGCAGGCGCAGCTGGAAGACAAGCGTGTACTGCTCGAGGTCACCGACGCTGCACGCAGTTGGC
TGGCGGCCGGTGGTTATGATGCGACGATGGGTGCGCGACCAATGGCGCGCTTGATTCAGGACAAGATCAAGCGTCCGCTG
GCGGAGGAGATTCTCTTTGGCGAACTGGCCGAGCATGGCGGTGTGGTACACATCGACATCAAGGATGGCGAGTTGACCTT
CGACTTTGAGACTACTGCTGAAATGGCCTGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (490-651)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (657-737)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (13-62)

• AAA lid domain (AAA_lid_9) (354-457)

• ATPase family associated with various cellular activities (AAA) (AAA) (215-326)

3D structure

• AlphaFold DB: A0A423H668

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	39.093	100	0.422
clpC	Streptococcus pneumoniae D39	39.043	100	0.41
clpC	Streptococcus pneumoniae TIGR4	39.043	100	0.41
clpC	Streptococcus pneumoniae Rx1	39.043	100	0.41
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.45	96.693	0.401
clpC	Streptococcus mutans UA159	41.748	95.37	0.398
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	37.265	100	0.393
clpC	Lactococcus lactis subsp. cremoris KW2	45.364	79.894	0.362