Detailed information NTG0136506

Bioinformatically predicted

Overview

• Name: comD/blpH
• Type: Regulator
• Locus tag: SanJ4211_RS02905
• Genome accession: NZ_CP012805
• Coordinates: 564823..565734 (-)
• Length: 303 a.a.
• NCBI ID: WP_235499515.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain J4211
• Function: phosphorylation of ComE; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 559823..570734

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SanJ4211_RS02885 (SanJ4211_0550c)	-	560159..560533 (-)	375	WP_037590248.1	hypothetical protein	-
SanJ4211_RS02890 (SanJ4211_0551)	comA/nlmT	561014..563164 (+)	2151	WP_003025436.1	peptide cleavage/export ABC transporter	Regulator
SanJ4211_RS02895 (SanJ4211_0552)	-	563175..564536 (+)	1362	WP_021001448.1	bacteriocin secretion accessory protein	-
SanJ4211_RS02900 (SanJ4211_0553)	-	564629..564778 (+)	150	WP_003025431.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
SanJ4211_RS02905 (SanJ4211_0554c)	comD/blpH	564823..565734 (-)	912	WP_235499515.1	sensor histidine kinase	Regulator
SanJ4211_RS02910 (SanJ4211_0555c)	comE/blpR	566135..566881 (-)	747	WP_037590320.1	response regulator transcription factor	Regulator
SanJ4211_RS02915 (SanJ4211_0556c)	-	567050..567763 (-)	714	WP_021001450.1	CPBP family intramembrane glutamic endopeptidase	-
SanJ4211_RS02920 (SanJ4211_0557)	-	567995..568219 (+)	225	WP_003025424.1	Blp family class II bacteriocin	-
SanJ4211_RS02925	-	568307..568627 (+)	321	WP_003037422.1	hypothetical protein	-
SanJ4211_RS02930 (SanJ4211_0558)	-	568635..568868 (+)	234	WP_003025420.1	garvicin Q family class II bacteriocin	-
SanJ4211_RS02935	-	568920..569210 (+)	291	WP_021001453.1	bacteriocin immunity protein	-
SanJ4211_RS02940 (SanJ4211_0559)	-	569362..569682 (+)	321	WP_057489587.1	hypothetical protein	-
SanJ4211_RS02945 (SanJ4211_0560)	-	569912..570142 (+)	231	WP_021001454.1	Blp family class II bacteriocin	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 34865.12 Da
• Isoelectric Point: 6.9327

>NTDB_id=136506 SanJ4211_RS02905 WP_235499515.1 564823..565734(-) (comD/blpH) [Streptococcus anginosus strain J4211]
MRLIQYNFKTLKSQKINHNDKKIIIFVNISMIIYHLIVQVLSYLENENNLQTLNFRESLVVLYLILFVSVANYLDRHLRE
RIQSDLMLQKDLQLKNLENYSHHIEELYTEVRSFRHDYANILTTLKLGIEQNDIGIVKNVYHSVLKDSNKRFRNPKYDIG
RLVHIKNDALKSLLAAKFAQAQEHNVSVSLEVPEDICPQGMELVDFITIVSILCDNAIEAATPTMTIAYVLSENKQVFSI
ENAIKEEHIDMSYIFDAGVSSKGSGRGIGLSNVLAILDRYPNVSLTSASQNYRFQHVLEIHLN

Nucleotide

• Length: 912 bp

>NTDB_id=136506 SanJ4211_RS02905 WP_235499515.1 564823..565734(-) (comD/blpH) [Streptococcus anginosus strain J4211]
TTGCGTTTAATTCAATATAATTTTAAGACATTAAAATCTCAAAAAATTAATCACAACGATAAGAAAATTATCATCTTTGT
AAATATCAGCATGATTATTTATCATCTTATTGTTCAAGTTCTATCTTATTTAGAAAATGAGAATAACTTACAGACACTAA
ATTTTAGAGAAAGTTTAGTAGTTCTTTATCTTATCCTTTTTGTGAGTGTTGCCAATTATTTAGACCGTCATTTACGAGAG
AGAATCCAAAGTGATTTAATGCTTCAAAAAGATTTACAGTTAAAAAACTTGGAAAACTACAGTCATCACATTGAGGAATT
GTACACAGAAGTTCGGAGCTTTCGGCATGATTACGCTAATATTTTAACAACCTTGAAATTAGGAATTGAGCAAAATGATA
TAGGCATTGTAAAGAATGTCTATCATTCTGTTTTGAAAGATTCCAATAAGCGTTTTCGCAATCCCAAGTATGATATTGGA
CGGTTAGTCCATATCAAAAACGATGCCTTAAAAAGCCTGCTAGCTGCTAAATTTGCACAAGCTCAAGAGCATAATGTATC
CGTTTCATTGGAGGTTCCAGAAGATATTTGTCCACAAGGAATGGAATTAGTTGACTTTATCACCATTGTCTCCATTTTGT
GTGATAATGCGATTGAAGCTGCCACTCCAACTATGACGATTGCTTATGTTTTGTCAGAAAACAAGCAGGTATTCTCCATT
GAAAATGCTATAAAAGAAGAGCATATAGACATGTCTTATATTTTTGATGCGGGAGTTAGTTCTAAAGGATCTGGGCGAGG
AATTGGATTATCAAATGTCTTAGCAATTCTGGATCGATATCCAAATGTTTCTCTTACTAGCGCTAGTCAAAATTATCGTT
TCCAGCATGTCCTTGAGATTCATCTGAATTAA

Domains

Predicted by InterProScan.

• GHKL domain (HATPase_c_5) (201-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comD/blpH	Streptococcus mutans UA159	44.014	93.729	0.413
comD/comD3	Streptococcus equinus JB1	37.793	98.68	0.373