Detailed information NTG0136482

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SanJ4211_RS01285
• Genome accession: NZ_CP012805
• Coordinates: 234032..236164 (+)
• Length: 710 a.a.
• NCBI ID: WP_057489561.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain J4211
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 229032..241164

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SanJ4211_RS01270 (SanJ4211_0225)	comGH	229288..230241 (+)	954	WP_021001235.1	class I SAM-dependent methyltransferase	Machinery gene
SanJ4211_RS01275 (SanJ4211_0226)	-	230288..231487 (+)	1200	WP_057489560.1	acetate kinase	-
SanJ4211_RS01280 (SanJ4211_0227)	glmS	231874..233688 (+)	1815	WP_049533317.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-
SanJ4211_RS01285 (SanJ4211_0228)	clpC	234032..236164 (+)	2133	WP_057489561.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SanJ4211_RS01290 (SanJ4211_0229)	ulaG	236205..236759 (+)	555	Protein_224	L-ascorbate 6-phosphate lactonase	-
SanJ4211_RS01295 (SanJ4211_0230)	recP/tkt	236870..238846 (+)	1977	WP_021001237.1	transketolase	Machinery gene
SanJ4211_RS01300 (SanJ4211_0231)	-	238942..239430 (+)	489	WP_003026974.1	prolyl-tRNA synthetase associated domain-containing protein	-
SanJ4211_RS01305 (SanJ4211_0232)	yajC	239533..239871 (+)	339	WP_003026971.1	preprotein translocase subunit YajC	-

Sequence

Protein

• Length: 710 a.a.
• Molecular weight: 78733.73 Da
• Isoelectric Point: 4.7504

>NTDB_id=136482 SanJ4211_RS01285 WP_057489561.1 234032..236164(+) (clpC) [Streptococcus anginosus strain J4211]
MNNNYNNFDNMDNLFNQLMGRMGGFNSENRRYLINGREVTPEEFAQYRATGKLPKQAVENQNPQMQGQTGAPKQDGILAK
LGRNLTEEARQDMLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISVDIS
GLEAGTQYRGSFEENIQNLVSEVKEAGNVILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGDLTVIGATTQDEYRN
TILKNAALARRFNEVKVNAPSAEDTYKILQGIRDLYEKHHNVILPDEVLKAAVDYSIQYIPQRSLPDKAIDLVDVTAAHL
AAQHPVTDVHTVEREIAEQKKKQEAAVEKEDFETALNAKMRIEELEKKIENHTEDMKVTATVNDVAESVERMTGIPVSQM
GTSDIERLKEMNARLKTKVIGQNEAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKEAIIR
LDMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVVTLLLQVLDDGRLTDGQGNTVNFK
NTVIIATSNAGFGYESFTGDEEKDRKIMDRLKPYFRPEFLNRFNAVIEFSHLGKEDLAEIVELMLDEVNQTLAKKDITLT
VTDAAKAYLAEEGYDEVMGVRPLRRVIEQQIRDKVTDYHLDHLDVKHLLADLKDGELVIEEATDDSATKA

Nucleotide

• Length: 2133 bp

>NTDB_id=136482 SanJ4211_RS01285 WP_057489561.1 234032..236164(+) (clpC) [Streptococcus anginosus strain J4211]
ATGAATAACAACTACAACAACTTTGATAATATGGATAATCTTTTCAATCAATTGATGGGAAGAATGGGCGGTTTTAATAG
TGAAAATCGGCGTTATCTCATCAATGGACGTGAAGTAACACCAGAAGAATTTGCACAATACCGAGCAACGGGGAAACTGC
CGAAACAAGCAGTAGAAAATCAAAATCCGCAAATGCAGGGACAAACAGGTGCTCCAAAACAAGATGGCATTTTAGCGAAG
TTGGGTCGTAATTTGACAGAGGAAGCGCGTCAAGATATGCTAGATCCCGTCATTGGGCGTAACAAGGAAATTCAAGAAAC
AGCTGAAATTCTGTCTCGTCGGACGAAGAATAATCCAGTGCTAGTCGGAGATGCTGGGGTTGGTAAGACCGCAGTTGTCG
AAGGTTTGGCACAAGCGATTGTCAACGGCGATGTCCCTGCTGCTATTAAAAATAAGGAAATTATTTCTGTAGATATTTCT
GGATTAGAAGCAGGTACGCAATATCGCGGTAGCTTTGAAGAAAATATTCAAAATTTGGTGTCTGAAGTGAAAGAAGCCGG
CAATGTCATTCTCTTCTTTGATGAAATTCATCAAATCCTTGGTGCTGGAAGCACAGGTGGAGACAGCGGCTCTAAAGGTT
TGGCAGACATTTTGAAACCAGCTCTTTCTCGCGGGGATTTAACTGTGATTGGTGCGACGACGCAAGATGAATACCGCAAT
ACCATTTTGAAAAATGCGGCTTTGGCTCGCCGTTTCAATGAAGTAAAAGTAAATGCTCCTTCTGCAGAAGATACTTATAA
GATTTTACAAGGAATTCGTGACTTATACGAAAAACATCACAATGTTATCTTGCCAGATGAAGTGTTAAAAGCGGCTGTGG
ATTATTCGATTCAATACATTCCGCAACGCAGTTTGCCAGATAAAGCGATTGACCTAGTGGATGTGACAGCGGCTCACTTA
GCAGCTCAACATCCTGTTACAGATGTGCATACAGTGGAACGTGAAATTGCAGAGCAAAAGAAAAAGCAAGAAGCTGCGGT
TGAAAAAGAAGACTTTGAAACTGCTTTGAATGCCAAGATGCGTATTGAAGAGCTAGAAAAAAAGATTGAAAATCATACGG
AAGACATGAAAGTGACTGCAACTGTCAATGATGTAGCCGAATCTGTAGAACGTATGACGGGTATTCCTGTTTCCCAAATG
GGGACTAGTGATATTGAACGGTTGAAAGAGATGAATGCGCGATTGAAGACAAAAGTCATTGGACAAAACGAAGCAGTTGA
AGCAGTGGCGCGCGCTATTCGTCGGAATCGTGCAGGTTTTGATGAAGGAAATCGTCCGATTGGTAGCTTCCTCTTTGTCG
GCCCAACTGGTGTTGGAAAAACAGAGCTAGCGAAGCAATTAGCGCTTGATATGTTTGGTACTAAAGAAGCCATTATCCGT
TTGGACATGTCTGAATACTCTGACCGCACGGCTGTGTCGAAGTTGATTGGTACAACAGCTGGTTATGTCGGCTATGATGA
CAACAGCAATACCTTGACAGAACGTGTTCGTCGGAATCCATACTCAATCATTTTACTAGACGAAATTGAAAAGGCCGATC
CGCAAGTCGTCACATTGTTACTACAAGTTTTGGATGATGGTCGTTTGACAGATGGGCAAGGAAATACTGTCAACTTTAAG
AATACAGTTATTATTGCTACGTCTAACGCTGGCTTTGGTTATGAAAGCTTTACAGGTGATGAGGAAAAGGATAGGAAGAT
TATGGATCGCTTAAAACCATACTTCCGCCCAGAATTCTTGAATCGCTTCAATGCAGTCATTGAATTCTCACACCTTGGTA
AAGAAGACTTGGCTGAAATTGTTGAATTGATGCTAGATGAAGTCAACCAAACGCTTGCTAAGAAAGACATCACTCTGACG
GTAACAGATGCCGCAAAAGCTTATCTAGCAGAAGAAGGTTACGATGAAGTCATGGGTGTTCGTCCGCTTCGCCGTGTGAT
TGAACAACAAATCCGTGACAAAGTAACAGATTATCATCTGGATCATTTGGATGTGAAACATCTCTTAGCTGACCTGAAAG
ATGGTGAATTAGTCATTGAGGAAGCAACAGATGATTCAGCTACAAAAGCATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (445-605)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (612-681)

• AAA lid domain (AAA_lid_9) (261-356)

• ATPase family associated with various cellular activities (AAA) (AAA) (120-252)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	49.55	93.803	0.465
clpE	Streptococcus mutans UA159	48.926	91.831	0.449
clpE	Streptococcus pneumoniae Rx1	48.58	89.296	0.434
clpE	Streptococcus pneumoniae D39	48.58	89.296	0.434
clpE	Streptococcus pneumoniae R6	48.58	89.296	0.434
clpE	Streptococcus pneumoniae TIGR4	48.499	89.155	0.432
clpC	Bacillus subtilis subsp. subtilis str. 168	47.059	90.986	0.428
clpC	Streptococcus pneumoniae Rx1	42.924	90.563	0.389
clpC	Streptococcus pneumoniae D39	42.924	90.563	0.389
clpC	Streptococcus pneumoniae TIGR4	42.768	90.563	0.387
clpC	Streptococcus mutans UA159	43.8	87.465	0.383
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.78	87.183	0.382
clpC	Streptococcus thermophilus LMD-9	42.788	86.901	0.372
clpC	Streptococcus thermophilus LMG 18311	42.626	86.901	0.37