Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   GBS85147_RS08755 Genome accession   NZ_CP010319
Coordinates   1752092..1754539 (-) Length   815 a.a.
NCBI ID   WP_053039170.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain GBS85147     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1747092..1759539
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GBS85147_RS08730 (GBS85147_1767) - 1747373..1748629 (+) 1257 WP_001285395.1 toxic anion resistance protein -
  GBS85147_RS08735 (GBS85147_1768) hslO 1748769..1749644 (+) 876 WP_000357827.1 Hsp33 family molecular chaperone HslO -
  GBS85147_RS08740 (GBS85147_1769) dusB 1749628..1750605 (+) 978 WP_000192735.1 tRNA dihydrouridine synthase DusB -
  GBS85147_RS08745 (GBS85147_1770) - 1750726..1751367 (+) 642 WP_000909522.1 deoxynucleoside kinase -
  GBS85147_RS08750 (GBS85147_1771) - 1751381..1751872 (+) 492 WP_000586896.1 GNAT family N-acetyltransferase -
  GBS85147_RS08755 (GBS85147_1772) clpC 1752092..1754539 (-) 2448 WP_053039170.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  GBS85147_RS08760 (GBS85147_1773) - 1754536..1755000 (-) 465 WP_000985641.1 CtsR family transcriptional regulator -
  GBS85147_RS08765 (GBS85147_1774) - 1755173..1755634 (+) 462 WP_001106578.1 small multi-drug export protein -
  GBS85147_RS08770 (GBS85147_1775) tsf 1755794..1756834 (-) 1041 WP_000808080.1 translation elongation factor Ts -
  GBS85147_RS08775 (GBS85147_1776) rpsB 1756927..1757697 (-) 771 WP_000268452.1 30S ribosomal protein S2 -
  GBS85147_RS08780 (GBS85147_1777) ahpC 1757974..1758534 (+) 561 WP_000060538.1 alkyl hydroperoxide reductase subunit C -

Sequence

Protein


Download         Length: 815 a.a.        Molecular weight: 90622.23 Da        Isoelectric Point: 6.2341

>NTDB_id=136385 GBS85147_RS08755 WP_053039170.1 1752092..1754539(-) (clpC) [Streptococcus agalactiae strain GBS85147]
MSHYSIKLQEVFRLAQFQAARYESHYLESWHLLLAMVLVHDSVAGLTFAEYESEVAIEEYEAATILALGRAPKEEITNYQ
FLEQSPALKKILKLAENISIVVGAEDVGTEHVLLAMLVNKDLLATRILELVGFRGQDDGESVRMVDLRKALERHAGFTKD
DIKAIYELRNPKKAKSGASFSDMMKPPSTAGDLADFTRDLSQMAVDGEIEPVIGRDKEISRMVQVLSRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGNIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIADIEEDGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVLVEEPNLEDAYEILLGLKPAYEAFHNVTISDE
AVMTAVKVAHRYLTSKNLPDSAIDLLDEASATVQMMIKKNAPSLLTEVDQAILDDDMKSASKALKASHKGKKRKPIAVTE
DHIMATLSRLSGIPVEKLTQADSKKYLNLEKELHKRVIGQDDAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRYDKTVGFGAKDISHDYTAMQKRIMEELKKAYRPEFINRIDEKVVFHS
LSQDNMREVVKIMVKPLILALKDKGMDLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLSELLLANQVKEGQVIK
IGVSKGKLKFDIAKS

Nucleotide


Download         Length: 2448 bp        

>NTDB_id=136385 GBS85147_RS08755 WP_053039170.1 1752092..1754539(-) (clpC) [Streptococcus agalactiae strain GBS85147]
ATGAGTCATTATTCCATAAAATTACAAGAAGTATTCAGATTGGCGCAATTTCAAGCAGCACGCTATGAAAGTCACTATTT
AGAAAGCTGGCATCTTCTTTTAGCAATGGTTTTAGTTCATGATTCAGTAGCTGGTTTGACATTTGCTGAATATGAGTCTG
AAGTTGCAATTGAAGAGTACGAAGCAGCAACAATTTTAGCTTTAGGTAGAGCACCGAAAGAAGAGATTACCAATTATCAA
TTTTTAGAGCAATCACCAGCTTTGAAAAAGATCTTAAAGTTAGCAGAAAATATTAGTATCGTAGTAGGAGCTGAAGATGT
GGGTACTGAACATGTCTTGCTTGCTATGTTGGTTAATAAAGATTTATTAGCCACACGTATCTTAGAATTAGTTGGCTTTA
GAGGTCAAGACGATGGTGAATCAGTTCGTATGGTTGATTTACGTAAGGCTCTAGAACGTCATGCCGGTTTTACAAAAGAT
GATATCAAAGCAATTTATGAATTACGTAATCCTAAAAAAGCAAAGTCGGGTGCTTCTTTTTCTGATATGATGAAACCACC
AAGTACTGCTGGTGATTTAGCTGATTTCACACGTGATTTATCACAGATGGCGGTTGATGGGGAAATTGAACCTGTTATTG
GGCGTGATAAAGAAATTTCACGTATGGTCCAAGTCTTAAGTCGTAAAACAAAGAATAATCCTGTCTTAGTTGGAGATGCG
GGTGTCGGTAAAACAGCTTTGGCGTACGGTCTAGCACAACGTATTGCTAATGGAAATATTCCTTATGAGCTTAGAGATAT
GCGTGTTCTAGAGTTAGATATGATGAGCGTTGTTGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGTATGAATCAAA
TCATTGCAGATATTGAAGAAGACGGTCATATTATTCTTTTCATTGATGAACTGCATACTATTATGGGTTCTGGCTCTGGT
ATTGATAGCACACTTGATGCTGCTAATATTTTAAAACCAGCTTTGGCTCGAGGCACTTTACGCACTGTTGGAGCAACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAAGATGCTGCTTTATCCCGTCGCTTTGCAAAAGTTTTAGTAGAAGAACCAA
ATCTTGAAGACGCATATGAAATTCTACTTGGATTGAAGCCAGCGTATGAAGCCTTTCATAATGTTACTATTTCAGATGAA
GCAGTTATGACTGCTGTAAAAGTGGCTCATCGTTATTTGACAAGTAAGAATTTACCAGACTCAGCTATAGACTTACTTGA
TGAAGCTTCTGCCACTGTGCAAATGATGATTAAGAAAAATGCTCCTTCGCTTTTAACAGAAGTTGACCAAGCTATTTTAG
ATGATGATATGAAATCTGCTTCTAAAGCTCTAAAAGCAAGTCATAAGGGTAAAAAGCGTAAGCCTATTGCCGTAACAGAA
GATCATATTATGGCAACTCTCAGTCGTCTATCTGGTATTCCTGTTGAAAAATTGACACAAGCTGATAGTAAAAAATACCT
CAATTTAGAAAAAGAATTGCATAAACGTGTTATCGGTCAAGATGATGCAGTTACTGCCATTAGTCGTGCTATCCGTCGCA
ATCAATCTGGCATTCGTACTGGTAAGCGTCCTATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTTGGTAAGACAGAG
TTAGCAAAAGCCTTGGCAGAAGTGTTGTTTGATGATGAATCAGCCCTAATTCGTTTTGATATGTCGGAATATATGGAAAA
ATTCGCAGCTTCTCGCCTGAATGGGGCACCTCCAGGTTATGTTGGTTATGATGAAGGAGGAGAGTTGACTGAAAAAGTAC
GCAATAAACCATATTCAGTTTTACTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTTAATGTATTATTACAAGTG
CTTGATGATGGCGTTTTAACAGATAGTCGAGGACGAAAAGTTGACTTTTCAAATACTATAATCATTATGACTTCTAATTT
AGGAGCAACTGCATTACGTTACGATAAAACAGTTGGTTTTGGAGCTAAGGATATCAGCCATGATTATACTGCTATGCAAA
AACGTATTATGGAGGAGCTTAAAAAAGCTTATCGACCGGAGTTTATCAATCGTATTGATGAGAAAGTTGTATTCCATAGT
CTCAGTCAAGATAATATGCGTGAAGTTGTGAAAATTATGGTTAAACCTTTAATTTTAGCGCTTAAAGATAAAGGTATGGA
TCTGAAATTCCAGCCTTCAGCCTTGAAACACTTGGCAGAGGATGGCTATGATATAGAAATGGGTGCTCGTCCACTGCGTA
GAACTATTCAAACGCAAGTAGAGGATCATTTATCAGAACTACTATTGGCAAATCAAGTGAAAGAGGGGCAAGTAATTAAG
ATTGGCGTATCCAAAGGCAAATTGAAATTTGATATTGCAAAATCATAA

Domains

Predicted by InterproScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(105-132)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-46)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-801)

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)

AAA lid domain (AAA_lid_9)

(375-470)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

76.355

99.632

0.761
  clpC Streptococcus thermophilus LMG 18311

72.761

100

0.728
  clpC Streptococcus thermophilus LMD-9

72.638

100

0.726
  clpC Streptococcus pneumoniae Rx1

68.55

99.877

0.685
  clpC Streptococcus pneumoniae D39

68.55

99.877

0.685
  clpC Streptococcus pneumoniae TIGR4

68.55

99.877

0.685
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.558

100

0.496
  clpC Bacillus subtilis subsp. subtilis str. 168

45.728

100

0.466
  clpE Streptococcus mutans UA159

46.238

78.282

0.362

Multiple sequence alignment