Detailed information NTG0136304

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: RP72_RS18625
• Genome accession: NZ_CP010314
• Coordinates: 3525728..3526321 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis subsp. subtilis strain 3NA isolate 1970 (Michel and Millet)
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3520728..3531321

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RP72_RS18595 (RP72_18595)	psmA	3520982..3521317 (+)	336	WP_003242480.1	SMR family transporter	-
RP72_RS18600 (RP72_18600)	psmB	3521317..3521637 (+)	321	WP_003228222.1	QacE family quaternary ammonium compound efflux SMR transporter	-
RP72_RS18605 (RP72_18605)	yvdQ	3521673..3522185 (-)	513	WP_003243249.1	DUF3231 family protein	-
RP72_RS18610 (RP72_18610)	cotNP	3522437..3523780 (-)	1344	WP_003228217.1	FAD-binding oxidoreductase	-
RP72_RS18615 (RP72_18615)	cotR	3524136..3525098 (+)	963	WP_003243674.1	sporulation hydrolase CotR	-
RP72_RS18625 (RP72_18625)	clpP	3525728..3526321 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
RP72_RS18630 (RP72_18630)	pgmB	3526367..3527047 (-)	681	WP_003228210.1	beta-phosphoglucomutase	-
RP72_RS18635 (RP72_18635)	malL	3527044..3528729 (-)	1686	WP_003243333.1	oligo-1,6-glucosidase	-
RP72_RS18640 (RP72_18640)	mdxK	3528722..3530996 (-)	2275	Protein_3595	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=136304 RP72_RS18625 WP_003228214.1 3525728..3526321(+) (clpP) [Bacillus subtilis subsp. subtilis strain 3NA isolate 1970 (Michel and Millet)]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=136304 RP72_RS18625 WP_003228214.1 3525728..3526321(+) (clpP) [Bacillus subtilis subsp. subtilis strain 3NA isolate 1970 (Michel and Millet)]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAAGCGA
CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538