Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SanJ4206_RS02040 Genome accession   NZ_CP012719
Coordinates   410366..410998 (+) Length   210 a.a.
NCBI ID   WP_003028406.1    Uniprot ID   A0ABR7CU49
Organism   Streptococcus anginosus strain J4206     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 405366..415998
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4206_RS02020 (SanJ4206_0364) - 405802..406542 (+) 741 WP_022525304.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SanJ4206_RS02025 (SanJ4206_0365) stkP 406539..408413 (+) 1875 WP_003028410.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SanJ4206_RS02030 (SanJ4206_0366) liaF 408674..409372 (+) 699 WP_003028409.1 cell wall-active antibiotics response protein LiaF -
  SanJ4206_RS02035 (SanJ4206_0367) - 409369..410364 (+) 996 WP_003028408.1 sensor histidine kinase -
  SanJ4206_RS02040 (SanJ4206_0368) vraR 410366..410998 (+) 633 WP_003028406.1 response regulator transcription factor Regulator
  SanJ4206_RS02045 (SanJ4206_0369) - 411038..412438 (+) 1401 WP_003028405.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SanJ4206_RS02050 (SanJ4206_0370) - 412440..412811 (+) 372 WP_003028404.1 S1 RNA-binding domain-containing protein -
  SanJ4206_RS02055 (SanJ4206_0371c) - 412940..413257 (-) 318 WP_003043378.1 DUF960 domain-containing protein -
  SanJ4206_RS02060 (SanJ4206_0372c) - 413377..413910 (-) 534 WP_003028401.1 DUF402 domain-containing protein -
  SanJ4206_RS02065 (SanJ4206_0373c) recX 413997..414773 (-) 777 WP_003028400.1 recombination regulator RecX -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23698.22 Da        Isoelectric Point: 4.6562

>NTDB_id=136038 SanJ4206_RS02040 WP_003028406.1 410366..410998(+) (vraR) [Streptococcus anginosus strain J4206]
MQILLVDDHEMVRLGLKGYLDLQDDVDVVAEASNGREGVEKALELHPDVIMMDIVMPEMNGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEDLTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=136038 SanJ4206_RS02040 WP_003028406.1 410366..410998(+) (vraR) [Streptococcus anginosus strain J4206]
ATGCAGATTTTATTAGTAGATGACCATGAAATGGTAAGACTTGGCTTGAAAGGTTATTTGGATTTACAAGACGATGTGGA
TGTAGTGGCAGAAGCTTCAAATGGTCGCGAAGGAGTTGAAAAAGCTTTGGAGTTGCACCCAGATGTGATTATGATGGACA
TTGTCATGCCTGAAATGAATGGGATTGAAGCGACGCTTGCCATTTTAAAAGAATGGCCTGAAGCTAAAATTCTCATTTTG
ACTTCTTATTTGGATAATGAAAAAATTTATCCAGTTTTAGATGCGGGTGCTAAAGGATATATGCTAAAAACTTCTAGTGC
TGATGATATTTTACGAGCGGTCCGAAAAGTAGCCAAGGGTGAACTTGCTATTGAAACAGAGGTCAGCCAAAAAGTAGAAT
ATCATCGAAATCATATTGAATTGCACGAAGATTTGACTGCGCGTGAGCGAGATATTTTAGGACTACTGGCAAAAGGTTAT
GAAAATCAACGCATAGCAGATGAATTATTTATTTCTTTAAAGACAGTGAAAACACATGTGTCCAATATCTTATCAAAGCT
AGAGGTGAGTGACCGTACACAAGCTGTTGTTTATGCTTTCCAACATCACCTTGTCCCACAAGATGACATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

98.095

0.533
  degU Bacillus subtilis subsp. subtilis str. 168

39.732

100

0.424

Multiple sequence alignment