Detailed information NTG0135899

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AN159_RS01415
• Genome accession: NZ_CP012694
• Coordinates: 259697..261976 (-)
• Length: 759 a.a.
• NCBI ID: WP_002236866.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain 331401
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 254697..266976

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AN159_RS01400 (AN159_01400)	-	255256..255852 (+)	597	WP_002235659.1	restriction endonuclease subunit S	-
AN159_RS01405 (AN159_01405)	-	255824..256474 (+)	651	WP_226893068.1	restriction endonuclease subunit S	-
AN159_RS14245	-	256553..259650 (+)	3098	Protein_270	HsdR family type I site-specific deoxyribonuclease	-
AN159_RS01415 (AN159_01425)	clpC	259697..261976 (-)	2280	WP_002236866.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
AN159_RS01420 (AN159_01430)	clpS	261978..262280 (-)	303	WP_002221161.1	ATP-dependent Clp protease adapter ClpS	-
AN159_RS01425 (AN159_01435)	-	262523..262726 (+)	204	WP_002217533.1	cold-shock protein	-
AN159_RS01430 (AN159_01440)	pmbA	263024..264355 (-)	1332	WP_050178618.1	metalloprotease PmbA	-
AN159_RS01435 (AN159_01445)	yjgA	264509..265021 (+)	513	WP_069972608.1	ribosome biogenesis factor YjgA	-
AN159_RS01440 (AN159_01450)	-	265068..265781 (+)	714	WP_002246107.1	hypothetical protein	-

Sequence

Protein

• Length: 759 a.a.
• Molecular weight: 83867.75 Da
• Isoelectric Point: 6.9734

>NTDB_id=135899 AN159_RS01415 WP_002236866.1 259697..261976(-) (clpC) [Neisseria meningitidis strain 331401]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDASVPNVLKLCGADLKVVSEQLAASVAENTPLIPEHLLDTVET
RPTLGFQRVMQRAMVHTQSAGKAAVEPLDVLVALMSETDSHTVYFLKLQSVTRFEVLRCIAHGSPDDEDGNDSDGLGREG
EEAEQKTGSLSDYTVNLNTEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALAEGLAHQIVNGGIPDA
LKDAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTSGGTMDASNLLKPALAKGSLRCI
GATTYDEYRTIFDKDYALSRRFQKIDVVEPTVSETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINERFLPDKAI
DVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVARIPEKTVSHDDKQVLQFLGRDLKNMVYGQENAIDALVAAVKMSRS
GLGLPDKPIGSFLFSGPTGVGKTEAAKQLAYSMGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNKQPHC
VLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPGLGFTAKRERGDEMQAINKLFTPE
FRNRLDAIIPFAPLSEPIIAKVVDKFLLRLEHRLLDKKVEAEFTPALRKYLARKGFDPQMGARPMHRLIQEKIRKPLADE
LLFGKLSNGGFVRIDWDAAKEEAVLKFKKSKVKPETETV

Nucleotide

• Length: 2280 bp

>NTDB_id=135899 AN159_RS01415 WP_002236866.1 259697..261976(-) (clpC) [Neisseria meningitidis strain 331401]
ATGCTTGCACCCGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCTCCGTGCCGAACGTCTTAAAACTATGCGGCGCGGATTTGAAAG
TGGTGTCCGAACAGCTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGAACACCTTTTAGACACGGTCGAAACC
CGGCCCACGCTCGGCTTCCAACGCGTGATGCAACGGGCGATGGTGCATACCCAGTCTGCCGGAAAAGCCGCAGTCGAACC
GTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACACCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCATGGCTCGCCCGATGACGAGGATGGCAATGATTCAGACGGCCTGGGACGCGAGGGC
GAAGAAGCGGAACAAAAAACCGGCTCCCTTTCCGACTACACCGTCAACCTCAACACCGAAGTCAAAGCCGGCCGTATCGA
CCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTATGCCGCCGCCGCAAAAACAATCCGCTTTTGG
TCGGCGAAGCAGGCGTGGGCAAAACCGCGCTGGCGGAAGGTTTGGCACATCAAATCGTCAACGGCGGCATTCCAGACGCG
CTTAAAGATGCCGAAGTGTACGCGCTGGATATGGGCTCGCTGTTGGCGGGCACGAAATACCGTGGCGACTTTGAAGCGCG
GGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTGTTTATCGACGAAATCCACACCATCATCGGCG
CAGGCAGCACCAGCGGCGGCACCATGGACGCGTCCAACCTGCTCAAACCCGCGCTGGCAAAAGGTTCGCTGCGCTGCATC
GGCGCAACCACCTACGACGAATACCGCACCATTTTCGACAAAGACTATGCCTTAAGCCGCCGCTTCCAAAAAATCGACGT
GGTCGAACCCACCGTTTCCGAAACCGTACAAATCCTGCGCGGCTTGAAGCCGATGTTTGAAGCCTTCCACCAAGTCCGCT
ATACGCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCACGCTACATCAACGAGCGTTTCCTGCCCGACAAAGCCATC
GACGTGATGGACGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACAGAAAAAAGTCATCGGCAAAGCGCAAAT
CGAAACCGTCATCGCCAAAGTCGCGCGGATTCCAGAAAAAACCGTGTCGCACGACGACAAACAGGTGCTGCAATTCCTCG
GCCGCGATTTGAAAAACATGGTTTACGGTCAAGAAAACGCCATCGACGCGCTGGTTGCCGCCGTCAAAATGTCGCGTTCG
GGCTTGGGACTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCGACCGGCGTGGGCAAAACCGAAGCCGCCAA
ACAGCTTGCCTACTCGATGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAACGCCATGCCGTATCGCGCC
TCATCGGCGCGCCTCCGGGCTACGTCGGCTTCGAACAAGGCGGCCTTTTGACCGAAGCCGTCAACAAACAGCCGCATTGC
GTGTTGCTCTTGGACGAAATCGAAAAAGCCCACCCCGACATTTTCAACGTCCTCCTGCAAGTCATGGACGCAGGCAAACT
GACCGACAACAACGGCAAGAGTGCCGATTTCCGCAACGTCATCCTGATTATGACCACCAACGCGGGCGCGGAAAGCCTCA
GCCGCCCCGGCCTCGGCTTTACCGCCAAGCGCGAACGCGGCGACGAAATGCAGGCCATCAACAAACTCTTCACGCCCGAG
TTCCGCAACCGCTTGGACGCGATTATCCCGTTTGCACCCCTGTCCGAACCCATTATCGCCAAAGTCGTGGACAAATTCCT
GCTCCGGCTCGAACACCGGCTCCTCGACAAGAAAGTCGAAGCCGAATTCACACCGGCATTGCGCAAATATCTGGCGAGAA
AAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGCAAACCGCTCGCCGACGAA
CTCCTGTTCGGCAAACTATCCAACGGCGGCTTCGTGCGGATAGACTGGGATGCGGCAAAAGAAGAAGCCGTGTTGAAATT
TAAGAAAAGCAAGGTTAAACCTGAAACAGAAACTGTTTAA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (212-343)

• AAA lid domain (AAA_lid_9) (352-448)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (654-734)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-61)

• AAA domain (Cdc48 subfamily) (AAA_2) (487-648)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	37.871	100	0.403
clpC	Bacillus subtilis subsp. subtilis str. 168	37.282	100	0.394
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.678	94.203	0.393
clpC	Streptococcus thermophilus LMG 18311	44.968	81.159	0.365
clpC	Streptococcus thermophilus LMD-9	44.805	81.159	0.364