Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RN80_RS03730 Genome accession   NZ_CP012646
Coordinates   729811..730443 (+) Length   210 a.a.
NCBI ID   WP_060627598.1    Uniprot ID   -
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 724811..735443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS03705 (RN80_03715) mvaD 725088..726041 (+) 954 WP_060627587.1 diphosphomevalonate decarboxylase -
  RN80_RS03710 (RN80_03720) - 726028..727035 (+) 1008 WP_060627589.1 phosphomevalonate kinase -
  RN80_RS03715 (RN80_03725) fni 727019..728029 (+) 1011 WP_060627591.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  RN80_RS03720 (RN80_03730) liaF 728107..728805 (+) 699 WP_060627594.1 cell wall-active antibiotics response protein LiaF -
  RN80_RS03725 (RN80_03735) - 728802..729797 (+) 996 WP_060627596.1 sensor histidine kinase -
  RN80_RS03730 (RN80_03740) vraR 729811..730443 (+) 633 WP_060627598.1 response regulator transcription factor Regulator
  RN80_RS03735 (RN80_03745) - 730722..731609 (+) 888 WP_060627601.1 C40 family peptidase -
  RN80_RS03740 (RN80_03750) - 731662..732852 (+) 1191 WP_060627603.1 N-acetylmuramoyl-L-alanine amidase family protein -
  RN80_RS03745 (RN80_03755) - 732942..734186 (+) 1245 WP_060627605.1 N-acetylmuramoyl-L-alanine amidase family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23654.23 Da        Isoelectric Point: 4.8048

>NTDB_id=135362 RN80_RS03730 WP_060627598.1 729811..730443(+) (vraR) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEAANGAQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGARGYMLKTSSADELLHAVRKVAAGELVIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=135362 RN80_RS03730 WP_060627598.1 729811..730443(+) (vraR) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGATGATGTGGA
AGTTGTAGGGGAAGCGGCCAATGGGGCTCAAGGCATTGACTTGGCCTTGGAATTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACTTTGGCCATCCTCAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACTTCGTACTTGGACAATGAAAAAATCATGCCGGTCTTGAACGCTGGTGCTAGAGGCTATATGCTTAAGACTTCTAGTGC
AGACGAACTACTCCATGCTGTTCGTAAGGTGGCTGCTGGAGAGTTGGTCATTGAGCAAGAGGTCAGCAAAAAAGTCGAAT
ACCACCGCAATCATATGGAGCTTCATGAGGAGTTGACTGCGCGTGAGCGAGATGTGCTCCAACTCATCGCCAAGGGCTAT
GAAAATCAGCGCATCGCAGACGAACTGTTTATCTCTCTCAAGACGGTCAAGACCCATGTGTCCAATATCCTAGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCACTTGGTGGGTCATGAAGACTTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-115)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.11

99.524

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414