Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   RN80_RS01300 Genome accession   NZ_CP012646
Coordinates   225894..228428 (-) Length   844 a.a.
NCBI ID   WP_060627234.1    Uniprot ID   -
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 220894..233428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS01285 (RN80_01295) - 221335..222024 (-) 690 WP_060627231.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
  RN80_RS01290 (RN80_01300) patB 222274..224040 (-) 1767 WP_060627232.1 multidrug efflux ABC transporter subunit PatB -
  RN80_RS01295 (RN80_01305) rcrP 224042..225748 (-) 1707 WP_060627233.1 multidrug efflux ABC transporter subunit PatA Regulator
  RN80_RS01300 (RN80_01310) hexA 225894..228428 (-) 2535 WP_060627234.1 DNA mismatch repair protein MutS Machinery gene
  RN80_RS01305 (RN80_01315) argR 228479..228925 (-) 447 WP_001231476.1 arginine repressor -
  RN80_RS01310 (RN80_01320) argS 229061..230752 (+) 1692 WP_060627235.1 arginine--tRNA ligase -
  RN80_RS01315 (RN80_01325) - 231130..231375 (+) 246 WP_000084858.1 hypothetical protein -
  RN80_RS01320 (RN80_01330) - 231545..232561 (+) 1017 WP_045610961.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -

Sequence

Protein


Download         Length: 844 a.a.        Molecular weight: 94735.24 Da        Isoelectric Point: 4.9810

>NTDB_id=135325 RN80_RS01300 WP_060627234.1 225894..228428(-) (hexA) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MATEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVAIDRDGSQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKEGFEDLHLLDSRLATVEQAASSKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIGKERIIQRQEVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIVQLDGIPELESLISAAIAP
EAPHVITEGGIIRTGFDETLDKYRRVLREGTSWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVSKYIQRIQALAQGIATVDVLQSLAVVAETQHLIRPEFG
DDSRIDIQKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAIMAQMGSYVPAESAYLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLQHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQETESPAPMRQTST
VSEQISLFDTPAVHPVLAELSKLDIYNMTPMQAMNVLVELKQKL

Nucleotide


Download         Length: 2535 bp        

>NTDB_id=135325 RN80_RS01300 WP_060627234.1 225894..228428(-) (hexA) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGGCGACAGAAAAGCTATCACCCGGCATGCAACAGTATGTGGATATTAAAAAGCAATATCCAGATGCTTTTTTGCTCTT
TCGTATGGGTGATTTTTATGAATTATTTTATGAGGATGCGGTCAATGCTGCGCAGATTCTGGAAATTTCCTTAACGAGTC
GCAACAAGAATGCCGACAATCCGATCCCTATGGCGGGTGTTCCCTATCATTCTGCCCAACAGTATATCGATGTCTTGATT
GAGCAGGGCTATAAGGTAGCCATTGCTGAACAGATGGAAGATCCTAAACAGGCAGTTGGGGTTGTGAAACGAGAGGTTGT
TCAGGTCATTACGCCAGGGACAGTGGTCGACAGTAGTAAGCCGGACAGTCAGAACAATTTCTTGGTTGCCATAGACCGTG
ATGGCAGTCAATTTGGCCTCGCTTATATGGACTTGGTGACGGGTGACTTTTATGTGACAGGTCTTTTGGATTTTACGCTG
GTTTGTGGGGAAATTCGTAACCTCAAGGCTCGAGAAGTGGTGCTGGGTTATGACTTGTCTGAGGAAGAAGAACAAATCCT
CAGTCGTCAGATGAATCTGGTACTTTCCTATGAAAAAGAAGGTTTTGAAGACCTTCATTTACTAGATTCACGATTGGCAA
CTGTGGAGCAAGCGGCATCTAGTAAGCTACTCCAGTATGTTCATCGGACTCAGATGAGAGAATTGAACCACCTCAAGCCT
GTTATCCGCTATGAAATCAAGGATTTCTTGCAGATGGATTATGCGACAAAGGCTAGTCTGGATTTGGTTGAGAATGCTCG
TTCAGGCAAGAAGCAAGGCAGTCTTTTCTGGCTTTTGGATGAAACCAAAACGGCTATGGGGATGCGTCTTTTGCGGTCTT
GGATCCATCGTCCTTTGATTGGTAAGGAACGAATCATCCAACGTCAAGAAGTGGTGCAGGTCTTCCTCGACCATTTCTTT
GAGCGCAGTGATTTGACAGACAGTCTCAAGGGAGTTTATGATATCGAACGATTGGCTAGTCGTGTTTCTTTTGGTAAAAC
CAATCCCAAGGATCTCTTGCAGTTGGCGACCACCTTATCTAGTGTGCCACGGATTCGTGCGATTTTAGAAGGGATGGAGC
AACCTGCTCTAGCCTATCTCATCGTACAACTGGATGGAATCCCTGAGTTGGAGAGTTTGATTAGCGCAGCGATTGCTCCT
GAAGCTCCTCATGTGATTACGGAAGGTGGTATTATCCGCACTGGATTTGATGAAACCTTAGACAAGTACCGTCGTGTGCT
CAGAGAAGGGACTAGCTGGATTGCTGAGATTGAGGCTAAGGAGCGAGAAAACTCTGGTATCAGTACCCTCAAGATTGACT
ACAATAAGAAGGATGGCTACTATTTCCATGTGACCAATTCGCAACTGGGAAATGTGCCTGCTCACTTTTTCCGCAAGGCG
ACGCTGAAAAACTCAGAACGTTTTGGAACCGAAGAATTGGCCCGTATCGAGGGAGATATGCTGGAGGCGCGTGAGAAGTC
AGCTAACCTCGAATACGAAATCTTTATGCGTATTCGTGAAGAAGTCAGCAAGTACATCCAACGTATACAAGCTCTAGCCC
AAGGAATTGCGACAGTTGATGTCTTACAGAGTCTGGCGGTTGTGGCTGAAACCCAGCATTTGATTCGACCTGAATTCGGA
GATGATTCGCGAATTGATATCCAGAAAGGGCGCCATGCTGTCGTTGAAAAGGTTATGGGGGCTCAGACCTATATTCCCAA
TACGATTCAGATGGCAGAAGATACCAGTATTCAACTGATTACAGGGCCCAACATGAGTGGGAAGTCTACCTACATGCGTC
AGTTAGCCATGACGGCGATAATGGCCCAGATGGGTTCCTATGTACCGGCTGAAAGCGCCTATTTACCGATTTTTGATGCG
ATTTTTACCCGTATCGGAGCAGCAGATGACTTGGTTTCAGGTCAATCAACTTTCATGGTGGAGATGATGGAGGCTAATAA
TGCCATTTCGCATGCGACCAAAAATTCCTTGATTCTTTTTGATGAATTGGGACGAGGAACTGCAACTTATGACGGGATGG
CTCTTGCTCAGTCTATCATCGAATATATCCATGAGCACATCGGAGCTAAGACCCTCTTTGCGACCCACTACCATGAGTTG
ACTAGTCTGGAGTCTAGTTTACAACACTTGGTTAATGTCCACGTGGCAACTTTGGAGCAGGATGGGCAGGTCACCTTCCT
TCACAAGATTGAACCAGGTCCAGCTGATAAATCCTATGGTATCCATGTTGCAAAGATTGCTGGCTTGCCAGCAGACCTTT
TAGCAAGGGCGGATAAGATTTTGACTCAGTTAGAGAATCAAGAGACAGAAAGTCCTGCTCCCATGAGGCAAACAAGTACT
GTCTCAGAACAAATTTCACTCTTTGACACGCCTGCAGTGCATCCTGTCCTAGCAGAATTGTCTAAACTGGACATTTACAA
CATGACACCCATGCAAGCTATGAATGTCTTGGTCGAGTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

MutS domain I (MutS_I)

(8-118)

MutS domain II (MutS_II)

(126-239)

MutS domain III (MutS_III)

(256-546)

MutS family domain IV (MutS_IV)

(415-505)

MutS domain V (MutS_V)

(599-785)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

95.972

100

0.96
  mutS Pseudomonas stutzeri strain ATCC 17587

36.534

100

0.37