Detailed information NTG0133801

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: AMM49_RS09975
• Genome accession: NZ_CP012480
• Coordinates: 1994549..1997125 (-)
• Length: 858 a.a.
• NCBI ID: WP_001118373.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain NGBS128
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1989549..2002125

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AMM49_RS09950 (AMM49_09940)	-	1989660..1990211 (-)	552	WP_000817340.1	DNA-3-methyladenine glycosylase I	-
AMM49_RS09955 (AMM49_09945)	ruvA	1990234..1990824 (-)	591	WP_000272489.1	Holliday junction branch migration protein RuvA	Machinery gene
AMM49_RS09960 (AMM49_09950)	-	1990826..1992058 (-)	1233	WP_000657474.1	MDR family MFS transporter	-
AMM49_RS09965 (AMM49_09955)	hexB	1992090..1994063 (-)	1974	WP_000034615.1	DNA mismatch repair endonuclease MutL	Machinery gene
AMM49_RS09970 (AMM49_09960)	-	1994289..1994492 (+)	204	WP_000191849.1	cold-shock protein	-
AMM49_RS09975 (AMM49_09965)	hexA	1994549..1997125 (-)	2577	WP_001118373.1	DNA mismatch repair protein MutS	Machinery gene
AMM49_RS09980 (AMM49_09970)	argR	1997182..1997619 (-)	438	WP_001033152.1	arginine repressor	-
AMM49_RS09985 (AMM49_09975)	argS	1997841..1999532 (+)	1692	WP_000379872.1	arginine--tRNA ligase	-
AMM49_RS09990 (AMM49_09980)	-	1999620..1999928 (+)	309	WP_001138859.1	bacteriocin immunity protein	-
AMM49_RS09995 (AMM49_09985)	-	1999955..2000827 (-)	873	WP_000915474.1	YitT family protein	-
AMM49_RS10000 (AMM49_09990)	-	2000935..2001879 (-)	945	WP_000857770.1	YitT family protein	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 97025.69 Da
• Isoelectric Point: 4.8723

>NTDB_id=133801 AMM49_RS09975 WP_001118373.1 1994549..1997125(-) (hexA) [Streptococcus agalactiae strain NGBS128]
MAKPTISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNAEKPIPMAGVPYHSAQQYIDVLV
ELGYKVAIAEQMEDPKKAVGVVKREVVQVVTPGTVVESTKPDSANNFLVAIDSQDQQTFGLAYMDVSTGEFQATLLTDFE
SVRSEILNLKAREIVVGYQLTDEKNHLLTKQMNLLLSYEDERLNDIHLIDEQLTDLEISAAEKLLQYVHRTQKRELSHLQ
KVVHYEIKDYLQMSYATKNSLDLLENARTSKKHGSLYWLLDETKTAMGTRMLRTWIDRPLVSMNRIKERQDIIQVFLDYF
FERNDLTESLKGVYDIERLASRVSFGKANPKDLLQLGQTLSQIPRIKMILQSFNQPELDIIVNKIDTMPELESLINTAIA
PEAQATITEGNIIKSGFDKQLDNYRTVMREGTGWIADIEAKERAASGIGTLKIDYNKKDGYYFHVTNSNLSLVPEHFFRK
ATLKNSERYGTAELAKIEGEMLEAREQSSNLEYDIFMRVRAQVESYIKRLQELAKTIATVDVLQSLAVVAENHHYVRPKF
NDEHQIKIKNGRHATVEKVMGVQEYIPNSIYFDSQTDIQLITGPNMSGKSTYMRQLALTVIMAQMGGFVSADEVDLPVFD
AIFTRIGAADDLISGQSTFMVEMMEANQAVKRASDKSLILFDELGRGTATYDGMALAQSIIEYIHDRVRAKTMFATHYHE
LTDLSEQLTRLVNVHVATLERDGEVTFLHKIEPGPADKSYGIHVAKIAGLPIDLLDRATDILSQLEADAVQLIVSAPQEA
VTADLNEELDPGKQQGQLSLFEEHSNAGRVIEELEAIDIMNLTPMQAMNAIFDLKKLL

Nucleotide

• Length: 2577 bp

>NTDB_id=133801 AMM49_RS09975 WP_001118373.1 1994549..1997125(-) (hexA) [Streptococcus agalactiae strain NGBS128]
ATGGCCAAGCCAACGATATCACCGGGAATGCAACAGTATCTGGATATAAAAGAGAATTATCCAGATGCTTTTTTGCTTTT
TAGAATGGGTGATTTTTATGAATTATTTTATGATGATGCGGTAAAAGCAGCACAAATCCTGGAAATTAGCTTGACTAGTC
GAAATAAGAACGCAGAAAAGCCAATCCCAATGGCAGGAGTTCCCTATCACTCAGCTCAACAGTATATTGACGTTTTAGTT
GAATTAGGTTACAAAGTAGCCATTGCTGAGCAGATGGAAGATCCTAAAAAAGCTGTGGGAGTGGTCAAGCGTGAGGTAGT
GCAAGTTGTTACCCCAGGAACGGTTGTGGAGTCAACGAAGCCGGATAGTGCTAATAATTTCTTAGTAGCGATTGATTCGC
AAGATCAACAAACATTTGGTCTAGCATATATGGATGTCTCAACTGGAGAGTTTCAGGCAACCCTTTTAACAGATTTTGAG
TCCGTCCGTAGTGAAATACTAAATTTAAAAGCTCGTGAGATTGTAGTAGGATATCAATTGACGGACGAAAAAAATCACCT
ACTGACGAAGCAGATGAACTTGCTTTTATCATACGAAGACGAACGACTTAATGATATTCATTTGATTGATGAGCAGTTAA
CTGATTTGGAAATATCTGCTGCGGAAAAACTTTTACAATATGTGCATAGAACACAAAAGCGTGAACTTAGTCATTTACAG
AAAGTAGTTCATTATGAAATAAAGGACTATTTACAAATGTCATATGCAACGAAAAATAGTCTAGATTTACTGGAGAATGC
TAGAACAAGCAAGAAGCACGGAAGTCTTTACTGGTTGTTAGATGAGACTAAAACAGCGATGGGAACTCGAATGCTGAGAA
CTTGGATTGACAGGCCTTTGGTAAGTATGAATCGAATCAAGGAACGTCAAGATATTATTCAAGTGTTTCTTGATTATTTT
TTTGAGAGAAACGATCTCACAGAAAGTTTAAAGGGTGTATATGATATTGAACGCCTAGCAAGTCGAGTATCTTTCGGAAA
AGCCAACCCTAAAGATCTATTGCAACTCGGACAGACCTTATCACAAATTCCTCGGATTAAAATGATTTTACAGTCCTTCA
ATCAACCTGAGCTTGACATCATTGTCAACAAAATTGACACTATGCCTGAATTAGAAAGTTTAATTAATACGGCGATAGCC
CCAGAAGCACAGGCTACTATCACTGAGGGAAACATTATCAAGTCTGGATTTGATAAGCAATTGGATAATTATCGAACAGT
GATGCGTGAAGGTACAGGTTGGATTGCTGATATTGAAGCTAAGGAAAGAGCAGCAAGTGGTATCGGTACCCTTAAAATTG
ATTATAATAAAAAAGACGGCTATTACTTCCATGTGACCAATTCCAATTTATCACTAGTACCGGAGCATTTTTTCCGTAAA
GCGACATTAAAAAATTCTGAACGCTATGGAACAGCAGAACTAGCCAAAATTGAAGGTGAAATGCTCGAAGCTCGCGAGCA
ATCTTCAAATTTAGAATATGATATTTTTATGCGTGTTCGTGCTCAAGTAGAATCTTATATTAAACGTCTTCAAGAGTTAG
CAAAGACTATTGCAACCGTTGATGTTCTACAGAGTTTGGCAGTAGTTGCAGAAAATCATCACTATGTTCGTCCCAAATTT
AATGATGAACATCAGATTAAGATTAAGAATGGGCGTCATGCAACCGTTGAAAAAGTGATGGGAGTGCAAGAATATATTCC
CAATAGTATCTATTTTGATAGTCAGACAGATATCCAGTTGATTACAGGACCAAATATGAGTGGTAAGTCGACCTATATGC
GCCAGTTAGCTCTGACAGTTATTATGGCACAAATGGGAGGTTTTGTATCGGCAGACGAAGTTGATTTGCCTGTATTTGAT
GCAATATTTACTAGGATTGGTGCTGCTGATGACTTAATTTCTGGGCAATCAACCTTTATGGTAGAAATGATGGAAGCGAA
TCAAGCTGTAAAACGAGCCAGTGATAAATCTTTGATTCTTTTTGATGAATTAGGTCGAGGGACAGCCACTTATGATGGTA
TGGCATTAGCTCAATCGATTATAGAATATATTCATGACCGTGTTAGGGCAAAAACAATGTTTGCAACTCATTACCATGAG
TTGACAGATTTATCTGAACAATTGACAAGGCTTGTCAATGTACACGTGGCTACTTTAGAGAGAGATGGAGAAGTTACCTT
CTTACATAAAATTGAACCTGGACCTGCGGACAAGTCTTATGGGATACACGTCGCAAAAATAGCTGGTTTACCAATTGACT
TATTGGATAGGGCAACTGATATTTTATCACAGTTGGAAGCTGATGCAGTACAGTTGATCGTATCAGCCCCCCAAGAAGCT
GTTACTGCTGACTTAAATGAGGAACTAGATCCTGGGAAGCAACAAGGACAATTATCGCTTTTTGAAGAACATTCAAATGC
AGGTAGGGTTATTGAGGAGTTAGAAGCGATAGATATAATGAATCTAACTCCAATGCAAGCTATGAATGCTATATTTGATT
TAAAGAAATTATTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-240)

• MutS domain V (MutS_V) (600-786)

• MutS domain III (MutS_III) (257-547)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (416-506)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	69.338	100	0.696
mutS	Pseudomonas stutzeri strain ATCC 17587	36.758	100	0.375