Detailed information NTG0133353

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DE8669_RS04560
• Genome accession: NZ_CP012391
• Coordinates: 872091..874382 (-)
• Length: 763 a.a.
• NCBI ID: WP_002223891.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain DE8669
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 867091..879382

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DE8669_RS15075 (DE8669_0852)	-	867217..867558 (+)	342	WP_061370943.1	restriction endonuclease subunit S	-
DE8669_RS14670 (DE8669_0853)	-	867579..868385 (+)	807	WP_306807197.1	restriction endonuclease subunit S	-
DE8669_RS04540	-	868372..868593 (+)	222	WP_033908706.1	hypothetical protein	-
DE8669_RS13745	-	868780..868889 (+)	110	Protein_869	IS5/IS1182 family transposase	-
DE8669_RS04555 (DE8669_0855)	-	868920..872051 (+)	3132	WP_014575271.1	type I restriction endonuclease subunit R	-
DE8669_RS04560 (DE8669_0856)	clpC	872091..874382 (-)	2292	WP_002223891.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
DE8669_RS04565 (DE8669_0857)	clpS	874384..874686 (-)	303	WP_002221161.1	ATP-dependent Clp protease adapter ClpS	-
DE8669_RS04570 (DE8669_0858)	-	874929..875132 (+)	204	WP_002217533.1	cold-shock protein	-
DE8669_RS04575 (DE8669_0859)	pmbA	875429..876760 (-)	1332	WP_002219485.1	metalloprotease PmbA	-
DE8669_RS04580 (DE8669_0860)	yjgA	876915..877421 (+)	507	WP_002219484.1	ribosome biogenesis factor YjgA	-
DE8669_RS04585 (DE8669_0861)	-	877468..878187 (+)	720	WP_002219483.1	hypothetical protein	-

Sequence

Protein

• Length: 763 a.a.
• Molecular weight: 84245.10 Da
• Isoelectric Point: 6.8224

>NTDB_id=133353 DE8669_RS04560 WP_002223891.1 872091..874382(-) (clpC) [Neisseria meningitidis strain DE8669]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDASVPNVLKLCGADLKVVSEQLAASVAENTPLIPEHLLDTVET
RPTLGFQRVMQRAMVHTQSAGKAAVEPLDVLVALMSETDSHTVYFLKLQSVTRFEVLRCIAHGSPDEDEDDGNYSSDGMD
DDNENRTKPGKNPLSAYTVNLNAEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALAEGLAHQIVNGG
IPDALKDAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTSGGTMDASNLLKPALAKGS
LRCIGATTYDEYRTIFDKDHALSRRFQKIDVVEPTVSETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINERFLP
DKAIDVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVARIPEKTVSHDDKQVLQFLGRDLKNMVYGQENAIDALVAAVK
MSRSGLALPDKPIGSFLFSGPTGVGKTEAAKQLAYSLGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNK
QPHCVLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPSLGFTAKRERGDEMQAINKL
FTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHQLLDKKVEAEFTSALHKYLAEKGFDPQMGARPMHRLIQEKIRKP
LADELLFGKLSDGGFVRIDWDAAKEEAVLKFKKSKVKIKTASA

Nucleotide

• Length: 2292 bp

>NTDB_id=133353 DE8669_RS04560 WP_002223891.1 872091..874382(-) (clpC) [Neisseria meningitidis strain DE8669]
ATGCTTGCACCCGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCTCCGTGCCGAACGTCTTAAAACTCTGCGGCGCGGATTTGAAAG
TGGTGTCCGAACAGCTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGAACACCTTTTAGACACGGTCGAAACA
CGGCCCACGCTCGGCTTCCAACGCGTGATGCAACGGGCGATGGTGCATACCCAGTCTGCCGGAAAAGCCGCAGTCGAACC
GTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACACCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCACGGCTCTCCCGATGAAGATGAAGACGATGGCAACTATTCTTCAGACGGCATGGAC
GACGATAATGAAAACCGCACCAAACCGGGCAAAAACCCTTTATCGGCGTACACCGTCAACCTCAACGCCGAAGTCAAAGC
CGGCCGTATCGACCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTATGCCGCCGCCGCAAAAACA
ATCCGCTTTTGGTCGGCGAAGCGGGCGTGGGCAAAACCGCGCTGGCGGAAGGTTTGGCACATCAAATCGTCAACGGCGGC
ATTCCAGACGCGCTCAAAGATGCCGAAGTGTACGCGCTGGATATGGGCTCGCTGTTGGCGGGCACGAAATACCGCGGCGA
CTTTGAAGCGCGGGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTGTTTATCGACGAAATCCACA
CCATCATCGGCGCAGGCAGCACCAGCGGCGGCACCATGGACGCGTCCAACCTGCTCAAACCCGCGCTGGCAAAAGGTTCG
CTGCGCTGCATCGGCGCGACCACTTACGACGAATACCGCACCATTTTCGACAAAGACCACGCCTTAAGCCGCCGCTTCCA
AAAAATCGACGTGGTCGAACCCACCGTTTCCGAAACCGTACAAATCCTGCGCGGCTTGAAGCCGATGTTTGAAGCCTTCC
ACCAAGTCCGCTATACGCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCACGCTACATCAACGAGCGTTTCCTGCCC
GACAAAGCCATCGACGTGATGGACGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACAGAAAAAAGTCATCGG
CAAAGCACAAATTGAAACCGTCATCGCCAAAGTTGCGCGGATTCCCGAAAAAACCGTGTCGCACGACGACAAACAAGTGC
TGCAATTCCTCGGTCGCGATTTGAAAAACATGGTTTACGGTCAAGAAAACGCCATCGACGCGCTGGTTGCCGCCGTCAAA
ATGTCGCGTTCCGGCCTTGCCCTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCGACCGGCGTGGGCAAAAC
CGAAGCCGCCAAACAGCTTGCCTACTCGCTGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAACGCCATG
CCGTATCGCGCCTCATCGGCGCGCCACCGGGCTACGTCGGCTTTGAACAAGGCGGCCTTTTGACCGAAGCCGTCAACAAA
CAGCCGCATTGCGTATTGCTCTTGGACGAAATCGAAAAAGCCCACCCCGACATTTTCAACGTCCTCCTGCAAGTCATGGA
CGCAGGCAAACTGACCGACAACAACGGCAAGAGTGCCGATTTCCGCAACGTCATCCTGATTATGACCACCAACGCAGGCG
CGGAAAGCCTCAGCCGCCCCAGCCTCGGCTTTACCGCCAAGCGCGAACGCGGCGACGAAATGCAGGCAATCAACAAGCTC
TTCACGCCCGAGTTCCGCAACCGCTTGGACGCGATTATCCCGTTTGCACCCTTGTCCGAACCCATCATCGTCAAAGTCGT
GGACAAATTCCTGCTCCAGCTCGAACACCAGCTCCTCGACAAAAAAGTCGAAGCCGAATTCACGTCGGCATTGCACAAAT
ATCTGGCGGAAAAAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGCAAACCG
CTCGCCGACGAACTCCTGTTCGGCAAACTATCCGACGGCGGCTTCGTGCGGATAGACTGGGATGCGGCAAAAGAAGAAGC
CGTGTTGAAGTTTAAGAAAAGCAAGGTCAAAATAAAAACCGCCTCCGCATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (491-652)

• AAA lid domain (AAA_lid_9) (356-453)

• ATPase family associated with various cellular activities (AAA) (AAA) (216-348)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (658-738)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-61)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.65	100	0.413
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.725	94.233	0.393
clpC	Bacillus subtilis subsp. subtilis str. 168	37.221	100	0.393