Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BF28_RS24860 Genome accession   NZ_CP009968
Coordinates   4263862..4264545 (-) Length   227 a.a.
NCBI ID   WP_000350710.1    Uniprot ID   Q81TR3
Organism   Bacillus cereus E33L     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 4258862..4269545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BF28_RS24845 (BF28_4409) pepF 4259043..4260869 (-) 1827 WP_000003397.1 oligoendopeptidase F Regulator
  BF28_RS24850 (BF28_4410) - 4260920..4262164 (-) 1245 WP_000612275.1 competence protein CoiA -
  BF28_RS24855 (BF28_4411) - 4262245..4263789 (-) 1545 WP_000799206.1 cardiolipin synthase -
  BF28_RS24860 (BF28_4412) mecA 4263862..4264545 (-) 684 WP_000350710.1 adaptor protein MecA Regulator
  BF28_RS24865 (BF28_4413) - 4264872..4265546 (+) 675 WP_000362618.1 TerC family protein -
  BF28_RS24870 (BF28_4414) spx 4265596..4265991 (-) 396 WP_000258267.1 transcriptional regulator Spx -
  BF28_RS24880 (BF28_4415) - 4266585..4266788 (+) 204 WP_000559980.1 hypothetical protein -
  BF28_RS24885 (BF28_4416) - 4266818..4268464 (-) 1647 WP_000728620.1 peptide ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26966.00 Da        Isoelectric Point: 3.9822

>NTDB_id=133243 BF28_RS24860 WP_000350710.1 4263862..4264545(-) (mecA) [Bacillus cereus E33L]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Nucleotide


Download         Length: 684 bp        

>NTDB_id=133243 BF28_RS24860 WP_000350710.1 4263862..4264545(-) (mecA) [Bacillus cereus E33L]
TTGGATATTGAAAGAATTAATGATCATACGATGAAATTTTTTATTACGTACATTGATATAGAGGACAGAGGCTTTAATCG
TGAGGAAATTTGGTATGACCGCGAAAGAAGCGAAGAGCTCTTTTGGGAAATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGGCCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCAGAACTT
TCAAAGGATGGACAAAAGCTAGAACTACCAATAGGTGTAGATAAAATTATAGACATTCCTCTAGATGAAGGTATTGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAAGAACAAGCAGGAACAAACTTTAACGAAGATGGTACATTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTCATTTCATTAAGTCACCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGGACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAGGAAGAAATTGATCGCATTTTAAG
TATTGTTTTAGAATACGGAGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGGAAACAAATTGTGAAAGAGC
ATGCGCTTGAAACAATTCGCAATAATTTTCCTGCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81TR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

56.14

100

0.564

Multiple sequence alignment