Detailed information NTG0133183

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: OY17_RS19665
• Genome accession: NZ_CP009938
• Coordinates: 4058772..4059935 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus sp. BH072 isolate honey
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4053772..4064935

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OY17_RS19635 (OY17_19635)	-	4054037..4054456 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
OY17_RS19640 (OY17_19640)	comFC	4054530..4055219 (-)	690	WP_197535984.1	ComF family protein	Machinery gene
OY17_RS19645 (OY17_19645)	-	4055225..4055509 (-)	285	WP_014419011.1	competence protein ComFB	-
OY17_RS19650 (OY17_19650)	comFA	4055567..4056952 (-)	1386	WP_014419012.1	DEAD/DEAH box helicase	Machinery gene
OY17_RS19655 (OY17_19655)	-	4057060..4057908 (-)	849	WP_003151387.1	DegV family protein	-
OY17_RS19660 (OY17_19660)	degU	4058006..4058695 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
OY17_RS19665 (OY17_19665)	degS	4058772..4059935 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
OY17_RS19670 (OY17_19670)	-	4060158..4060805 (+)	648	WP_007614107.1	YigZ family protein	-
OY17_RS19675 (OY17_19675)	-	4060810..4062024 (+)	1215	WP_014419013.1	LCP family protein	-
OY17_RS19680 (OY17_19680)	-	4062114..4063190 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
OY17_RS19685 (OY17_19685)	-	4063323..4064519 (-)	1197	WP_014419014.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=133183 OY17_RS19665 WP_007407484.1 4058772..4059935(-) (degS) [Bacillus sp. BH072 isolate honey]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=133183 OY17_RS19665 WP_007407484.1 4058772..4059935(-) (degS) [Bacillus sp. BH072 isolate honey]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951