Detailed information NTG0132918

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SSAL8618_RS07965
• Genome accession: NZ_CP009913
• Coordinates: 1745783..1748023 (-)
• Length: 746 a.a.
• NCBI ID: WP_038676610.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain NCTC 8618
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1740783..1753023

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSAL8618_RS07945 (SSAL8618_07945)	-	1741646..1742506 (-)	861	WP_002884335.1	methionyl aminopeptidase	-
SSAL8618_RS07950 (SSAL8618_07950)	spxR	1742551..1743831 (-)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
SSAL8618_RS07955 (SSAL8618_07955)	-	1743824..1744369 (-)	546	WP_013991031.1	GNAT family N-acetyltransferase	-
SSAL8618_RS07960 (SSAL8618_07960)	-	1744435..1745697 (-)	1263	WP_002884638.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SSAL8618_RS07965 (SSAL8618_07965)	comEC/celB	1745783..1748023 (-)	2241	WP_038676610.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SSAL8618_RS07970 (SSAL8618_07970)	comEA	1748013..1748708 (-)	696	WP_022496133.1	helix-hairpin-helix domain-containing protein	Machinery gene
SSAL8618_RS07975 (SSAL8618_07975)	-	1748817..1749574 (-)	758	Protein_1544	lysophospholipid acyltransferase family protein	-
SSAL8618_RS07980 (SSAL8618_07980)	-	1749704..1750639 (+)	936	WP_052124418.1	polysaccharide deacetylase family protein	-
SSAL8618_RS07985 (SSAL8618_07985)	-	1750689..1751453 (+)	765	WP_038676615.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
SSAL8618_RS07990 (SSAL8618_07990)	-	1751457..1751727 (+)	271	Protein_1547	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84420.30 Da
• Isoelectric Point: 9.9046

>NTDB_id=132918 SSAL8618_RS07965 WP_038676610.1 1745783..1748023(-) (comEC/celB) [Streptococcus salivarius strain NCTC 8618]
MWLKKAPINLFSLALLIAALYFTIFNTNVYAIGVLSFLLGCFLKHHWKNKVALKLVGLVGSFFLVYFLFLHHRATIQDKQ
APTEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKIKLSLAIGQRNFQGFNYQSY
LASQGIYRMAQIERLDHVVPQKSLSPLAFFHQLRRRALVHIQTHFPSPMRHYMTGLLFGYLGKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTFYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFALSGLVIFSQINPLFEWMEAFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEASQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSKLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMVSYPNLKASVLKAGHHGSKGSSSEAFLDQLQPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQNGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=132918 SSAL8618_RS07965 WP_038676610.1 1745783..1748023(-) (comEC/celB) [Streptococcus salivarius strain NCTC 8618]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCTTGGCTCTGTTAATAGCTGCCCTTTATTTTACGATTTTTAACAC
AAATGTTTATGCTATTGGGGTTTTGTCTTTTCTTTTAGGATGTTTTTTGAAGCATCATTGGAAGAATAAGGTAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCACCACAGAGCTACCATACAAGATAAACAA
GCTCCTACTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTGTCGGTTAATGGTGAGCAATTATCAGCTATTGGAAA
GGCAAAGGGACAAACTTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGCCAAA
CGTTGGTATTAAAAGGGAAAATAAAGTTATCCCTAGCAATTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTCAAGGCATTTATCGAATGGCTCAGATTGAACGCTTGGACCATGTGGTGCCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCATTGGTTCATATCCAGACGCACTTTCCTAGTCCTATGAGACACTATATGA
CAGGTCTGCTCTTTGGGTATTTGGGTAAGGAGTTTGATGAGCAAAGTCAGCTTTACACAAGCTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTATGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATCTTGCTGCCTTTTTCCTTGTGTTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCC
TGATTCAAAGTTTGTTAGCGGAGTTTGGTATTAAAAAACTGGATAATATGGGGATAACTTTGCTTCTATTGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTTTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTACGAGCTTAGTGTTGAGTCTTGGGATTTTGCCTTTTCTAACTTTCTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTATTTGATAGCTTTCTCTTGCCTGTATTGACA
GTCTTCTTTGCTCTTTCAGGACTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGGCCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTCTTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGGTCAAAGGAAAAATGGCAAGAGGCTAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTACCTACAGGCTAGGGGAGTGTCTCAAATTGACCATCTGGTCCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAACGCCCAGTTCGCACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGTAGTTTTTTGTTTACGGGTGATCTAGAAAAAGAAGGAGAGGAGGAACTGATGGTCAGCTATCCTAATTTAAA
GGCTAGTGTCCTCAAAGCCGGACACCACGGTTCAAAAGGGTCATCGTCTGAAGCGTTTTTGGACCAGTTGCAGCCCTCCC
TTGCCCTTGTTTCAGCTGGTGAGAATAATCGTTATAAACATCCAAATGATGAAACTTTGGAGCGTTTCAAGGAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGTGCTATCCGTTTTAAGGGGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (29-169)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.594	100	0.487
comEC/celB	Streptococcus mitis SK321	48.262	100	0.484
comEC/celB	Streptococcus pneumoniae Rx1	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae D39	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae R6	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae TIGR4	47.059	100	0.472
comEC	Lactococcus lactis subsp. cremoris KW2	43.514	99.196	0.432