Detailed information NTG0132902

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: SSAL8618_RS04925
• Genome accession: NZ_CP009913
• Coordinates: 1005728..1006435 (+)
• Length: 235 a.a.
• NCBI ID: WP_002884978.1
• Uniprot ID: A0AB33ZBK5
• Organism: Streptococcus salivarius strain NCTC 8618
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1000728..1011435

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSAL8618_RS04895 (SSAL8618_04895)	-	1001234..1001422 (+)	189	WP_013990684.1	DNA-directed RNA polymerase subunit beta	-
SSAL8618_RS04900 (SSAL8618_04900)	endA	1001483..1002364 (+)	882	WP_038675882.1	DNA/RNA non-specific endonuclease	Machinery gene
SSAL8618_RS04905 (SSAL8618_04905)	-	1002440..1003090 (-)	651	WP_002886253.1	amino acid ABC transporter permease	-
SSAL8618_RS04910 (SSAL8618_04910)	-	1003102..1003800 (-)	699	WP_002886251.1	amino acid ABC transporter permease	-
SSAL8618_RS04915 (SSAL8618_04915)	-	1003818..1004651 (-)	834	WP_037611665.1	transporter substrate-binding domain-containing protein	-
SSAL8618_RS04920 (SSAL8618_04920)	-	1004661..1005428 (-)	768	WP_038675884.1	amino acid ABC transporter ATP-binding protein	-
SSAL8618_RS04925 (SSAL8618_04925)	vicR	1005728..1006435 (+)	708	WP_002884978.1	response regulator YycF	Regulator
SSAL8618_RS04930 (SSAL8618_04930)	vicK	1006428..1007771 (+)	1344	WP_038675887.1	cell wall metabolism sensor histidine kinase VicK	Regulator
SSAL8618_RS04935 (SSAL8618_04935)	vicX	1007777..1008586 (+)	810	WP_126405093.1	MBL fold metallo-hydrolase	Regulator
SSAL8618_RS04940 (SSAL8618_04940)	-	1008645..1009004 (+)	360	WP_037611660.1	YbaN family protein	-
SSAL8618_RS04945 (SSAL8618_04945)	-	1009056..1010270 (-)	1215	WP_038675892.1	aminoacyltransferase	-
SSAL8618_RS04950 (SSAL8618_04950)	yidA	1010272..1011081 (-)	810	WP_002890845.1	sugar-phosphatase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27045.90 Da
• Isoelectric Point: 4.8387

>NTDB_id=132902 SSAL8618_RS04925 WP_002884978.1 1005728..1006435(+) (vicR) [Streptococcus salivarius strain NCTC 8618]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=132902 SSAL8618_RS04925 WP_002884978.1 1005728..1006435(+) (vicR) [Streptococcus salivarius strain NCTC 8618]
ATGAAAAAAATTCTAGTTGTTGATGACGAAAGACCGATTTCGGACATCATCAAGTTTAACCTGACAAAAGAAGGTTATGA
AGTGGTTACGGCTTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCATACACCAATTATCATGCTCTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGACTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACCTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGCA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTTGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATTTGGCAACTCATATGGGACAAGTGATGACGCGTGAGCATTTGCTTGAAAC
TGTTTGGGGCTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.687	99.149	0.8
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.559	100	0.387