Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SSAL8618_RS02000 Genome accession   NZ_CP009913
Coordinates   390894..392213 (+) Length   439 a.a.
NCBI ID   WP_038675337.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC 8618     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 385894..397213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSAL8618_RS01975 (SSAL8618_01975) - 386732..387496 (+) 765 WP_002883723.1 ABC transporter ATP-binding protein -
  SSAL8618_RS01980 (SSAL8618_01980) - 387496..388206 (+) 711 WP_002883761.1 ABC transporter ATP-binding protein -
  SSAL8618_RS01985 (SSAL8618_01985) - 388341..389000 (+) 660 WP_038675333.1 CBS and ACT domain-containing protein -
  SSAL8618_RS01990 (SSAL8618_01990) cysK 389185..390111 (-) 927 WP_002883742.1 cysteine synthase A -
  SSAL8618_RS01995 (SSAL8618_01995) - 390213..390839 (-) 627 WP_038675335.1 YigZ family protein -
  SSAL8618_RS02000 (SSAL8618_02000) comFA/cflA 390894..392213 (+) 1320 WP_038675337.1 DEAD/DEAH box helicase Machinery gene
  SSAL8618_RS02005 (SSAL8618_02005) - 392194..392856 (+) 663 WP_038675340.1 ComF family protein -
  SSAL8618_RS02010 (SSAL8618_02010) hpf 392935..393483 (+) 549 WP_002883786.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50631.59 Da        Isoelectric Point: 8.9020

>NTDB_id=132888 SSAL8618_RS02000 WP_038675337.1 390894..392213(+) (comFA/cflA) [Streptococcus salivarius strain NCTC 8618]
MVPKEYYGRLFTKEQLPVDYHSEAFTLESMIKVDKKLRCKRCYSQIEEDWQLPEGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPVLKWLGELTPYQAEVSEKLLETYQKQKDSLVHAVTGAGKTEMIYKIVAYVLESKGNVAIASPRVDVCRELFLR
MQRDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
LSLEEQVRLGSLEKHHLARRFHGNPLVLPKFCWQGRLQKSLMRGKLPRPLVYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQNYLPDEKMAFVSSKSEERSATVENFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=132888 SSAL8618_RS02000 WP_038675337.1 390894..392213(+) (comFA/cflA) [Streptococcus salivarius strain NCTC 8618]
ATGGTACCTAAAGAATATTATGGACGGCTATTTACGAAAGAACAGTTGCCAGTGGACTATCACTCAGAGGCTTTTACATT
AGAAAGCATGATAAAGGTCGATAAAAAACTTAGATGTAAAAGATGTTACAGTCAGATAGAGGAAGATTGGCAATTACCGG
AAGGTCAGTATTATTGCAGAGCGTGTATTGTCTTTGGCAGAAACCAAGAAGGAAAAGAACTTTATTATTTTCCTTCAAAA
ACATCAGAAATTGAGTTTCCTGTTTTGAAGTGGTTGGGAGAACTGACTCCCTATCAAGCTGAGGTCTCAGAGAAGCTTTT
AGAAACATATCAAAAACAGAAAGACAGCCTCGTACATGCTGTGACTGGTGCTGGGAAGACCGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGAAAGTAAAGGTAATGTAGCTATCGCAAGTCCTCGGGTTGATGTTTGTCGAGAGTTATTTCTTCGT
ATGCAGAGGGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACCCATCAACTACTAAAGTTTTACCAGAACTTTGACCTAGTTATCGTTGATGAGGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAGGAAACCGGTCGCTATATTTATTTAACAGCGACTTCTACA
TTATCTTTAGAGGAGCAAGTGCGACTTGGATCTTTAGAAAAGCATCACCTTGCTAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTGCTGGCAGGGAAGACTACAAAAATCTCTAATGAGAGGCAAGCTTCCAAGACCTCTTGTTTATCAGA
TTAAAAAGCAACGTAAATCAAAGTTTCCTCTATTAATCTTTTTTCCAAATATAGCGATAGGTGAAAAGTTCACTAGCATT
CTACAAAACTATCTTCCAGATGAAAAAATGGCCTTTGTTTCCTCAAAAAGTGAGGAGCGTTCAGCTACCGTAGAGAACTT
CCGAGAAAAAGAGTTATCCATTTTAGTGACAACAACTATCCTCGAACGTGGTGTGACCTTTCCACAAGTAGATGTTTTTG
TTTGCATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATAGGAGGTCGAGTTGGAAGATCTCCAGATAGA
CCGACAGGGAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCTATGCTTCGTTGTCGAGAAGAAATAAAAGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-170)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

56.613

98.178

0.556
  comFA/cflA Streptococcus pneumoniae D39

56.613

98.178

0.556
  comFA/cflA Streptococcus pneumoniae R6

56.613

98.178

0.556
  comFA/cflA Streptococcus pneumoniae TIGR4

56.613

98.178

0.556
  comFA/cflA Streptococcus mitis NCTC 12261

55.76

98.861

0.551
  comFA/cflA Streptococcus mitis SK321

54.988

98.178

0.54
  comFA Lactococcus lactis subsp. cremoris KW2

45.714

95.672

0.437
  comFA Latilactobacillus sakei subsp. sakei 23K

37.844

99.317

0.376

Multiple sequence alignment