Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | SAGV69_RS00440 | Genome accession | NZ_CP009681 |
| Coordinates | 90056..91402 (-) | Length | 448 a.a. |
| NCBI ID | WP_000816499.1 | Uniprot ID | Q9R3W9 |
| Organism | Staphylococcus aureus strain Gv69 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 40887..91402 | 90056..91402 | within | 0 |
Gene organization within MGE regions
Location: 40887..91402
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SAGV69_RS00165 (SAGV69_00035) | - | 40887..42566 (+) | 1680 | WP_016187646.1 | recombinase family protein | - |
| SAGV69_RS00170 (SAGV69_00036) | - | 42655..42993 (+) | 339 | WP_000175892.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| SAGV69_RS00175 (SAGV69_00038) | - | 43087..43398 (+) | 312 | WP_001166716.1 | DUF960 family protein | - |
| SAGV69_RS00180 (SAGV69_00039) | - | 43414..43920 (+) | 507 | WP_000848380.1 | DUF1643 domain-containing protein | - |
| SAGV69_RS00185 (SAGV69_00040) | - | 43941..44258 (+) | 318 | WP_000659046.1 | JAB domain-containing protein | - |
| SAGV69_RS00190 (SAGV69_00041) | - | 44377..45462 (+) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| SAGV69_RS17300 (SAGV69_04176) | - | 45459..47355 (+) | 1897 | Protein_36 | site-specific integrase | - |
| SAGV69_RS00205 | - | 47362..47740 (+) | 379 | Protein_37 | DUF6262 family protein | - |
| SAGV69_RS16855 (SAGV69_04191) | ant(9) | 47891..48673 (+) | 783 | Protein_38 | aminoglycoside nucleotidyltransferase ANT(9) | - |
| SAGV69_RS00215 | erm(A) | 48799..49530 (-) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| SAGV69_RS00220 (SAGV69_00785) | - | 50064..50726 (+) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| SAGV69_RS17305 | - | 50958..51104 (+) | 147 | Protein_41 | JAB domain-containing protein | - |
| SAGV69_RS00225 (SAGV69_00052) | - | 51274..52146 (+) | 873 | WP_000373151.1 | HTH domain-containing protein | - |
| SAGV69_RS00230 (SAGV69_00053) | - | 52203..52493 (+) | 291 | WP_000065262.1 | hypothetical protein | - |
| SAGV69_RS00235 (SAGV69_00054) | - | 52509..52997 (+) | 489 | WP_000397419.1 | hypothetical protein | - |
| SAGV69_RS00245 (SAGV69_04177) | - | 53130..54302 (-) | 1173 | Protein_45 | IS256-like element IS256 family transposase | - |
| SAGV69_RS00250 (SAGV69_00057) | - | 54464..54991 (+) | 528 | WP_000717928.1 | hypothetical protein | - |
| SAGV69_RS00255 (SAGV69_00058) | - | 55053..55469 (+) | 417 | WP_000941331.1 | hypothetical protein | - |
| SAGV69_RS17190 | - | 55758..55922 (+) | 165 | WP_001803222.1 | hypothetical protein | - |
| SAGV69_RS00260 (SAGV69_00060) | - | 55936..56157 (+) | 222 | WP_001070883.1 | hypothetical protein | - |
| SAGV69_RS00265 (SAGV69_00061) | - | 56293..56871 (+) | 579 | WP_020444591.1 | PepSY domain-containing protein | - |
| SAGV69_RS00270 (SAGV69_00062) | - | 56951..59164 (-) | 2214 | Protein_51 | type I restriction endonuclease subunit R | - |
| SAGV69_RS00280 (SAGV69_03258) | - | 60184..61530 (+) | 1347 | WP_000163428.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| SAGV69_RS00285 (SAGV69_03257) | merR | 61830..62237 (+) | 408 | WP_000425271.1 | Hg(II)-responsive transcriptional regulator MerR | - |
| SAGV69_RS17480 | - | 62254..62608 (+) | 355 | Protein_55 | TlpA disulfide reductase family protein | - |
| SAGV69_RS00295 (SAGV69_00067) | - | 62605..63285 (+) | 681 | WP_000010351.1 | cytochrome c biogenesis protein CcdA | - |
| SAGV69_RS00300 (SAGV69_00068) | - | 63420..63758 (+) | 339 | WP_000968575.1 | hypothetical protein | - |
| SAGV69_RS00305 (SAGV69_00069) | merA | 63816..65459 (+) | 1644 | WP_000193219.1 | mercury(II) reductase | - |
| SAGV69_RS00310 (SAGV69_04175) | merB | 65541..66190 (+) | 650 | Protein_59 | organomercurial lyase MerB | - |
| SAGV69_RS00315 (SAGV69_00070) | - | 66385..66915 (-) | 531 | WP_041205518.1 | hypothetical protein | - |
| SAGV69_RS00320 (SAGV69_00071) | - | 66951..67625 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| SAGV69_RS15955 | - | 67709..68050 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| SAGV69_RS00330 (SAGV69_00073) | - | 68927..69670 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| SAGV69_RS00335 (SAGV69_00074) | - | 69767..70195 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| SAGV69_RS00340 (SAGV69_00075) | mecA | 70241..72250 (-) | 2010 | WP_078056052.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| SAGV69_RS00345 (SAGV69_00076) | mecR1 | 72347..74104 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| SAGV69_RS00350 | mecI | 74104..74475 (+) | 372 | Protein_67 | mecA-type methicillin resistance repressor MecI | - |
| SAGV69_RS16870 (SAGV69_00078) | psm-mec | 74560..74628 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| SAGV69_RS00355 (SAGV69_00079) | - | 74948..76096 (+) | 1149 | WP_000427807.1 | ROK family transcriptional regulator | - |
| SAGV69_RS00365 (SAGV69_00081) | cstB | 76211..77545 (-) | 1335 | Protein_70 | persulfide dioxygenase-sulfurtransferase CstB | - |
| SAGV69_RS00370 (SAGV69_00082) | - | 77576..78640 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| SAGV69_RS00375 | cstR | 78776..79036 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| SAGV69_RS00380 (SAGV69_00084) | - | 79036..79674 (+) | 639 | Protein_73 | sulfite exporter TauE/SafE family protein | - |
| SAGV69_RS00385 (SAGV69_00085) | - | 79948..80565 (-) | 618 | WP_000562107.1 | CadD family cadmium resistance transporter | - |
| SAGV69_RS00390 (SAGV69_00086) | - | 80646..83060 (-) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| SAGV69_RS00395 (SAGV69_00087) | - | 83053..83418 (-) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| SAGV69_RS00400 (SAGV69_00088) | - | 83656..84033 (-) | 378 | WP_000361060.1 | DUF6262 family protein | - |
| SAGV69_RS00405 (SAGV69_00089) | - | 84040..85932 (-) | 1893 | WP_020444597.1 | site-specific integrase | - |
| SAGV69_RS00410 (SAGV69_00091) | - | 86127..86450 (-) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| SAGV69_RS00415 | - | 86443..86648 (-) | 206 | Protein_80 | hypothetical protein | - |
| SAGV69_RS00420 (SAGV69_00093) | - | 86650..87171 (-) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| SAGV69_RS00425 (SAGV69_00094) | - | 87190..87501 (-) | 312 | WP_000833212.1 | DUF960 family protein | - |
| SAGV69_RS00430 | - | 87586..87936 (-) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| SAGV69_RS00435 (SAGV69_00096) | ccrB | 88407..90035 (-) | 1629 | WP_001186596.1 | recombinase family protein | Machinery gene |
| SAGV69_RS00440 (SAGV69_00097) | ccrA | 90056..91402 (-) | 1347 | WP_000816499.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 448 a.a. Molecular weight: 52138.19 Da Isoelectric Point: 10.1760
>NTDB_id=131117 SAGV69_RS00440 WP_000816499.1 90056..91402(-) (ccrA) [Staphylococcus aureus strain Gv69]
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
Nucleotide
Download Length: 1347 bp
>NTDB_id=131117 SAGV69_RS00440 WP_000816499.1 90056..91402(-) (ccrA) [Staphylococcus aureus strain Gv69]
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
78.174 |
100 |
0.783 |
| ccrA | Staphylococcus aureus N315 |
72.383 |
100 |
0.725 |